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- W4294804669 abstract "Calcium imaging is an invaluable technique to detect and characterize calcium flux in cells. The use of calcium dye provides information on the concentration and spatial distribution of calcium. Calcium imaging is a well-established technique to assess the calcium-induced calcium release mechanism in cardiomyocytes. It can also be used to characterize mutations in genes crucial for this mechanism that frequently causes arrhythmia. Here we describe a high-throughput methodology of calcium imaging that records individual calcium transients in more than 10,000 human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) in less than 30 min." @default.
- W4294804669 created "2022-09-06" @default.
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- W4294804669 date "2022-01-01" @default.
- W4294804669 modified "2023-09-30" @default.
- W4294804669 title "Pharmacogenomic Screening of Drug Candidates using Patient-Specific hiPSC-Derived Cardiomyocyte High-Throughput Calcium Imaging" @default.
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- W4294804669 doi "https://doi.org/10.1007/978-1-0716-2573-6_10" @default.
- W4294804669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36068467" @default.
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