Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294916436> ?p ?o ?g. }
- W4294916436 endingPage "224001" @default.
- W4294916436 startingPage "224001" @default.
- W4294916436 abstract "Abstract Objective. In the era of precision medicine, human tumor atlas-oriented studies have been significantly facilitated by high-resolution, multi-modal tissue based microscopic pathology image analytics. To better support such tissue-based investigations, we have developed Digital Pathology Laboratory (DPLab), a publicly available web-based platform, to assist biomedical research groups, non-technical end users, and clinicians for pathology whole-slide image visualization, annotation, analysis, and sharing via web browsers. Approach. A major advancement of this work is the easy-to-follow methods to reconstruct three-dimension (3D) tissue image volumes by registering two-dimension (2D) whole-slide pathology images of serial tissue sections stained by hematoxylin and eosin (H&E), and immunohistochemistry (IHC). The integration of these serial slides stained by different methods provides cellular phenotype and pathophysiologic states in the context of a 3D tissue micro-environment. DPLab is hosted on a publicly accessible server and connected to a backend computational cluster for intensive image analysis computations, with results visualized, downloaded, and shared via a web interface. Main results. Equipped with an analysis toolbox of numerous image processing algorithms, DPLab supports continued integration of community-contributed algorithms and presents an effective solution to improve the accessibility and dissemination of image analysis algorithms by research communities. Significance. DPLab represents the first step in making next generation tissue investigation tools widely available to the research community, enabling and facilitating discovery of clinically relevant disease mechanisms in a digital 3D tissue space." @default.
- W4294916436 created "2022-09-08" @default.
- W4294916436 creator A5002100490 @default.
- W4294916436 creator A5051162009 @default.
- W4294916436 creator A5054762777 @default.
- W4294916436 creator A5066949209 @default.
- W4294916436 creator A5068392610 @default.
- W4294916436 creator A5070784245 @default.
- W4294916436 creator A5073283527 @default.
- W4294916436 creator A5076465098 @default.
- W4294916436 creator A5078484855 @default.
- W4294916436 date "2022-11-09" @default.
- W4294916436 modified "2023-10-17" @default.
- W4294916436 title "An integrative web-based software tool for multi-dimensional pathology whole-slide image analytics" @default.
- W4294916436 cites W1263520557 @default.
- W4294916436 cites W1798186455 @default.
- W4294916436 cites W1907124864 @default.
- W4294916436 cites W1974694769 @default.
- W4294916436 cites W1977653087 @default.
- W4294916436 cites W2060173426 @default.
- W4294916436 cites W2072120417 @default.
- W4294916436 cites W2073943895 @default.
- W4294916436 cites W2087573146 @default.
- W4294916436 cites W2107554012 @default.
- W4294916436 cites W2111547563 @default.
- W4294916436 cites W2139484679 @default.
- W4294916436 cites W2150506962 @default.
- W4294916436 cites W2154813452 @default.
- W4294916436 cites W2234666690 @default.
- W4294916436 cites W2529543999 @default.
- W4294916436 cites W2586646489 @default.
- W4294916436 cites W2604857886 @default.
- W4294916436 cites W2607759647 @default.
- W4294916436 cites W2628196379 @default.
- W4294916436 cites W2760826191 @default.
- W4294916436 cites W2765185445 @default.
- W4294916436 cites W2766986246 @default.
- W4294916436 cites W2782738121 @default.
- W4294916436 cites W2789989802 @default.
- W4294916436 cites W2794803511 @default.
- W4294916436 cites W2952481429 @default.
- W4294916436 cites W2981907326 @default.
- W4294916436 cites W3004882697 @default.
- W4294916436 cites W363173866 @default.
- W4294916436 doi "https://doi.org/10.1088/1361-6560/ac8fde" @default.
- W4294916436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36067783" @default.
- W4294916436 hasPublicationYear "2022" @default.
- W4294916436 type Work @default.
- W4294916436 citedByCount "0" @default.
- W4294916436 crossrefType "journal-article" @default.
- W4294916436 hasAuthorship W4294916436A5002100490 @default.
- W4294916436 hasAuthorship W4294916436A5051162009 @default.
- W4294916436 hasAuthorship W4294916436A5054762777 @default.
- W4294916436 hasAuthorship W4294916436A5066949209 @default.
- W4294916436 hasAuthorship W4294916436A5068392610 @default.
- W4294916436 hasAuthorship W4294916436A5070784245 @default.
- W4294916436 hasAuthorship W4294916436A5073283527 @default.
- W4294916436 hasAuthorship W4294916436A5076465098 @default.
- W4294916436 hasAuthorship W4294916436A5078484855 @default.
- W4294916436 hasBestOaLocation W42949164362 @default.
- W4294916436 hasConcept C142724271 @default.
- W4294916436 hasConcept C151730666 @default.
- W4294916436 hasConcept C154945302 @default.
- W4294916436 hasConcept C199360897 @default.
- W4294916436 hasConcept C2522767166 @default.
- W4294916436 hasConcept C2777522853 @default.
- W4294916436 hasConcept C2777655017 @default.
- W4294916436 hasConcept C2777904410 @default.
- W4294916436 hasConcept C2779343474 @default.
- W4294916436 hasConcept C36464697 @default.
- W4294916436 hasConcept C41008148 @default.
- W4294916436 hasConcept C71924100 @default.
- W4294916436 hasConcept C79158427 @default.
- W4294916436 hasConcept C86803240 @default.
- W4294916436 hasConceptScore W4294916436C142724271 @default.
- W4294916436 hasConceptScore W4294916436C151730666 @default.
- W4294916436 hasConceptScore W4294916436C154945302 @default.
- W4294916436 hasConceptScore W4294916436C199360897 @default.
- W4294916436 hasConceptScore W4294916436C2522767166 @default.
- W4294916436 hasConceptScore W4294916436C2777522853 @default.
- W4294916436 hasConceptScore W4294916436C2777655017 @default.
- W4294916436 hasConceptScore W4294916436C2777904410 @default.
- W4294916436 hasConceptScore W4294916436C2779343474 @default.
- W4294916436 hasConceptScore W4294916436C36464697 @default.
- W4294916436 hasConceptScore W4294916436C41008148 @default.
- W4294916436 hasConceptScore W4294916436C71924100 @default.
- W4294916436 hasConceptScore W4294916436C79158427 @default.
- W4294916436 hasConceptScore W4294916436C86803240 @default.
- W4294916436 hasFunder F4320306076 @default.
- W4294916436 hasFunder F4320337350 @default.
- W4294916436 hasFunder F4320337351 @default.
- W4294916436 hasIssue "22" @default.
- W4294916436 hasLocation W42949164361 @default.
- W4294916436 hasLocation W42949164362 @default.
- W4294916436 hasLocation W42949164363 @default.
- W4294916436 hasOpenAccess W4294916436 @default.
- W4294916436 hasPrimaryLocation W42949164361 @default.
- W4294916436 hasRelatedWork W1975795843 @default.