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• W4294919150 abstract "Abstract Objective . Improving the local uniformity of <?CDATA ${B}_{1}^{+}$?> <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML overflow=scroll> <mml:msubsup> <mml:mrow> <mml:mi>B</mml:mi> </mml:mrow> <mml:mrow> <mml:mn>1</mml:mn> </mml:mrow> <mml:mrow> <mml:mo>+</mml:mo> </mml:mrow> </mml:msubsup> </mml:math> field for awake monkey brain magnetic resonance imaging (MRI) at ultra-high fields while facilitating convenient placement and fixation of MRI-compatible multimodal devices for neuroscience study, can eventually advance our understanding of the primate’s brain organization. Approach . A group of single-channel RF coils including conventional loop coils and loopole coils sharing the same size and shape were designed for comparison; their performance as the transmit coil was quantitatively evaluated through a series of numerical electromagnetic (EM) simulations, and further verified by using 7T MRI over a saline phantom and a monkey in vivo. Main results . Compared to conventional loop coils, the optimized loopole coil brought up to 23.5% <?CDATA ${B}_{1}^{+}$?> <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML overflow=scroll> <mml:msubsup> <mml:mrow> <mml:mi>B</mml:mi> </mml:mrow> <mml:mrow> <mml:mn>1</mml:mn> </mml:mrow> <mml:mrow> <mml:mo>+</mml:mo> </mml:mrow> </mml:msubsup> </mml:math> uniformity improvement for monkey brain imaging in EM simulations, and this performance was further verified over monkey brain imaging at 7T in vivo . Importantly, we have systematically explored the underlying mechanism regarding the relationship between loopole coils’ current density distribution and <?CDATA ${B}_{1}^{+}$?> <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML overflow=scroll> <mml:msubsup> <mml:mrow> <mml:mi>B</mml:mi> </mml:mrow> <mml:mrow> <mml:mn>1</mml:mn> </mml:mrow> <mml:mrow> <mml:mo>+</mml:mo> </mml:mrow> </mml:msubsup> </mml:math> uniformity, observing that it can be approximated as a sinusoidal curve. Significance . The proposed loopole coil design can improve the imaging quality in awake and behaving monkeys, thus benefiting advanced brain research at UHF." @default.
• W4294919150 created "2022-09-08" @default.
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• W4294919150 date "2022-09-23" @default.
• W4294919150 modified "2023-09-30" @default.
• W4294919150 title "The design and evaluation of single-channel loopole coils at 7T MRI" @default.
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• W4294919150 doi "https://doi.org/10.1088/1361-6560/ac8fdf" @default.
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