Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294920800> ?p ?o ?g. }
- W4294920800 abstract "Abstract Background Bone regeneration research is currently ongoing in the scientific community. Materials approved for clinical use, and applied to patients, have been developed and produced. However, rather than directly affecting bone regeneration, these materials support bone induction, which regenerates bone. Therefore, the research community is still researching bone tissue regeneration. In the papers published so far, it is hard to find an improvement in the theory of bone regeneration. This review discusses the relationship between the existing theories on hard tissue growth and regeneration and the biomaterials developed so far for this purpose and future research directions. Mainbody Highly complex nucleation and crystallization in hard tissue involves the coordinated action of ions and/or molecules that can produce different organic and inorganic composite biomaterials. In addition, the healing of bone defects is also affected by the dynamic conditions of ions and nutrients in the bone regeneration process. Inorganics in the human body, especially calcium- and/or phosphorus-based materials, play an important role in hard tissues. Inorganic crystal growth is important for treating or remodeling the bone matrix. Biomaterials used in bone tissue regeneration require expertise in various fields of the scientific community. Chemical knowledge is indispensable for interpreting the relationship between biological factors and their formation. In addition, sources of energy for the nucleation and crystallization processes of such chemical bonds and minerals that make up the bone tissue must be considered. However, the exact mechanism for this process has not yet been elucidated. Therefore, a convergence of broader scientific fields such as chemistry, materials, and biology is urgently needed to induce a distinct bone tissue regeneration mechanism. Conclusion This review provides an overview of calcium- and/or phosphorus-based inorganic properties and processes combined with organics that can be regarded as matrices of these minerals, namely collagen molecules and collagen fibrils. Furthermore, we discuss how this strategy can be applied to future bone tissue regenerative medicine in combination with other academic perspectives." @default.
- W4294920800 created "2022-09-08" @default.
- W4294920800 creator A5025551054 @default.
- W4294920800 creator A5035851446 @default.
- W4294920800 creator A5050008313 @default.
- W4294920800 creator A5057408046 @default.
- W4294920800 creator A5062317501 @default.
- W4294920800 date "2022-09-06" @default.
- W4294920800 modified "2023-10-10" @default.
- W4294920800 title "Biomineralization of bone tissue: calcium phosphate-based inorganics in collagen fibrillar organic matrices" @default.
- W4294920800 cites W1536843438 @default.
- W4294920800 cites W1601577933 @default.
- W4294920800 cites W1697383392 @default.
- W4294920800 cites W1801166380 @default.
- W4294920800 cites W1894430106 @default.
- W4294920800 cites W1963987683 @default.
- W4294920800 cites W1966872418 @default.
- W4294920800 cites W1968659017 @default.
- W4294920800 cites W1968853364 @default.
- W4294920800 cites W1969062343 @default.
- W4294920800 cites W1969794321 @default.
- W4294920800 cites W1973438039 @default.
- W4294920800 cites W1976221789 @default.
- W4294920800 cites W1976912963 @default.
- W4294920800 cites W1977671514 @default.
- W4294920800 cites W1978466655 @default.
- W4294920800 cites W1979847090 @default.
- W4294920800 cites W1980176045 @default.
- W4294920800 cites W1980751943 @default.
- W4294920800 cites W1981076043 @default.
- W4294920800 cites W1981277281 @default.
- W4294920800 cites W1981691840 @default.
- W4294920800 cites W1983090947 @default.
- W4294920800 cites W1983601534 @default.
- W4294920800 cites W1986445506 @default.
- W4294920800 cites W1987530640 @default.
- W4294920800 cites W1988853039 @default.
- W4294920800 cites W1990454260 @default.
- W4294920800 cites W1991889593 @default.
- W4294920800 cites W1992992979 @default.
- W4294920800 cites W1994298995 @default.
- W4294920800 cites W1994703716 @default.
- W4294920800 cites W1996010063 @default.
- W4294920800 cites W1996391760 @default.
- W4294920800 cites W1997198472 @default.
- W4294920800 cites W1997211717 @default.
- W4294920800 cites W1998992909 @default.
- W4294920800 cites W2000177708 @default.
- W4294920800 cites W2001923641 @default.
- W4294920800 cites W2002049934 @default.
- W4294920800 cites W2002382580 @default.
- W4294920800 cites W2003087026 @default.
- W4294920800 cites W2004118070 @default.
- W4294920800 cites W2005415088 @default.
- W4294920800 cites W2005601953 @default.
- W4294920800 cites W2006799813 @default.
- W4294920800 cites W2007574249 @default.
- W4294920800 cites W2007654689 @default.
- W4294920800 cites W2008177382 @default.
- W4294920800 cites W2009420944 @default.
- W4294920800 cites W2010280268 @default.
- W4294920800 cites W2012394932 @default.
- W4294920800 cites W2012610216 @default.
- W4294920800 cites W2014628167 @default.
- W4294920800 cites W2017174795 @default.
- W4294920800 cites W2017258814 @default.
- W4294920800 cites W2019295836 @default.
- W4294920800 cites W2020913954 @default.
- W4294920800 cites W2022641082 @default.
- W4294920800 cites W2026791619 @default.
- W4294920800 cites W2029289576 @default.
- W4294920800 cites W2029376783 @default.
- W4294920800 cites W2032741311 @default.
- W4294920800 cites W2033290176 @default.
- W4294920800 cites W2036491402 @default.
- W4294920800 cites W2036731181 @default.
- W4294920800 cites W2039572697 @default.
- W4294920800 cites W2039602359 @default.
- W4294920800 cites W2040713035 @default.
- W4294920800 cites W2040742266 @default.
- W4294920800 cites W2041455826 @default.
- W4294920800 cites W2042591533 @default.
- W4294920800 cites W2042850726 @default.
- W4294920800 cites W2043049240 @default.
- W4294920800 cites W2048379336 @default.
- W4294920800 cites W2048873760 @default.
- W4294920800 cites W2050694690 @default.
- W4294920800 cites W2051959338 @default.
- W4294920800 cites W2055041875 @default.
- W4294920800 cites W2057727525 @default.
- W4294920800 cites W2060122532 @default.
- W4294920800 cites W2060587653 @default.
- W4294920800 cites W2061168477 @default.
- W4294920800 cites W2061999079 @default.
- W4294920800 cites W2064199247 @default.
- W4294920800 cites W2066056548 @default.
- W4294920800 cites W2067220566 @default.
- W4294920800 cites W2067711057 @default.
- W4294920800 cites W2068849149 @default.
- W4294920800 cites W2076754203 @default.