FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294927214> ?p ?o ?g. }

• W4294927214 abstract "The interval between neoadjuvant immunochemotherapy and surgery in patients with non-small cell lung cancer (NSCLC) has not been well characterized. This study investigated the association between the time-to-surgery (TTS) interval and surgical-pathological outcomes.Clinical data of patients who received neoadjuvant immun-ochemotherapy followed by surgery for NSCLC between January 2019 and September 2021 were collected. The patients were divided into three groups based on TTS interval: the early-surgery group (ESG), the standard-surgery group (SSG), and the delayed-surgery group (DSG). The primary outcomes were objective response rate (ORR), major pathological response (MPR), and pathological complete response (pCR). The secondary endpoint was surgical outcome.Of the 171 patients, 16 (9.4%) received surgery in ≤28 days, 49 (28.7%) received surgery within 29-42 days, and 106 (61.9%) received surgery in ≥43 days after neoadjuvant immunochemotherapy, with a median TTS of 46 days. The postoperative drainage of the ESG group (455.1 ml) was significantly less than that of the SSG group (680.7 ml) and the DSG group (846.5 ml; p = 0.037). However, the TTS interval did not influence the duration of the operation (P = 0.54), the extent of intraoperative bleeding (P = 0.60), or the length of postoperative hospital stay (P = 0.17). The ORR was observed in 69%, 51%, and 56% of patients in the ESG, the SSG, and the DSG, respectively (P = 0.46), and MPR occurred in 50%, 47%, and 58% (P = 0.38) of patients in the ESG, the SSG, and the DSG, respectively. Similarly, no statistically significant difference was found for pCR (ESG: 31%; SSG: 27%; DSG: 42%; P = 0.14).This retrospective study indicated that TTS exerts no significant effect on the feasibility and safety of surgery in the neoadjuvant immunochemotherapy setting of NSCLC. Analysis of the TTS interval revealed a tendency for delayed surgery to be associated with a pathological response in NSCLC, although this association was not statistically significant." @default.
• W4294927214 created "2022-09-08" @default.
• W4294927214 creator A5024380193 @default.
• W4294927214 creator A5028225823 @default.
• W4294927214 creator A5050842056 @default.
• W4294927214 creator A5068142532 @default.
• W4294927214 creator A5078938441 @default.
• W4294927214 date "2022-09-07" @default.
• W4294927214 modified "2023-09-26" @default.
• W4294927214 title "Impact of the interval between neoadjuvant immunochemotherapy and surgery on surgical–pathological outcomes in non-small cell lung cancer" @default.
• W4294927214 cites W2163281697 @default.
• W4294927214 cites W2216643583 @default.
• W4294927214 cites W2228221433 @default.
• W4294927214 cites W2313818615 @default.
• W4294927214 cites W2346515796 @default.
• W4294927214 cites W2537726651 @default.
• W4294927214 cites W2768209852 @default.
• W4294927214 cites W2769635882 @default.
• W4294927214 cites W2782812540 @default.
• W4294927214 cites W2798160602 @default.
• W4294927214 cites W2894584497 @default.
• W4294927214 cites W2911188335 @default.
• W4294927214 cites W2920151666 @default.
• W4294927214 cites W2947779096 @default.
• W4294927214 cites W2979156429 @default.
• W4294927214 cites W3014405676 @default.
• W4294927214 cites W3030259932 @default.
• W4294927214 cites W3089266118 @default.
• W4294927214 cites W3117368271 @default.
• W4294927214 cites W3120555797 @default.
• W4294927214 cites W3120983932 @default.
• W4294927214 cites W3124196524 @default.
• W4294927214 cites W3129084386 @default.
• W4294927214 cites W3135829537 @default.
• W4294927214 cites W3137579707 @default.
• W4294927214 cites W4226382697 @default.
• W4294927214 doi "https://doi.org/10.3389/fonc.2022.909726" @default.
• W4294927214 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36158657" @default.
• W4294927214 hasPublicationYear "2022" @default.
• W4294927214 type Work @default.
• W4294927214 citedByCount "0" @default.
• W4294927214 crossrefType "journal-article" @default.
• W4294927214 hasAuthorship W4294927214A5024380193 @default.
• W4294927214 hasAuthorship W4294927214A5028225823 @default.
• W4294927214 hasAuthorship W4294927214A5050842056 @default.
• W4294927214 hasAuthorship W4294927214A5068142532 @default.
• W4294927214 hasAuthorship W4294927214A5078938441 @default.
• W4294927214 hasBestOaLocation W42949272141 @default.
• W4294927214 hasConcept C121608353 @default.
• W4294927214 hasConcept C126322002 @default.
• W4294927214 hasConcept C141071460 @default.
• W4294927214 hasConcept C168563851 @default.
• W4294927214 hasConcept C203092338 @default.
• W4294927214 hasConcept C207886595 @default.
• W4294927214 hasConcept C2776256026 @default.
• W4294927214 hasConcept C2778078201 @default.
• W4294927214 hasConcept C2778292576 @default.
• W4294927214 hasConcept C2992528526 @default.
• W4294927214 hasConcept C530470458 @default.
• W4294927214 hasConcept C71924100 @default.
• W4294927214 hasConceptScore W4294927214C121608353 @default.
• W4294927214 hasConceptScore W4294927214C126322002 @default.
• W4294927214 hasConceptScore W4294927214C141071460 @default.
• W4294927214 hasConceptScore W4294927214C168563851 @default.
• W4294927214 hasConceptScore W4294927214C203092338 @default.
• W4294927214 hasConceptScore W4294927214C207886595 @default.
• W4294927214 hasConceptScore W4294927214C2776256026 @default.
• W4294927214 hasConceptScore W4294927214C2778078201 @default.
• W4294927214 hasConceptScore W4294927214C2778292576 @default.
• W4294927214 hasConceptScore W4294927214C2992528526 @default.
• W4294927214 hasConceptScore W4294927214C530470458 @default.
• W4294927214 hasConceptScore W4294927214C71924100 @default.
• W4294927214 hasLocation W42949272141 @default.
• W4294927214 hasLocation W42949272142 @default.
• W4294927214 hasLocation W42949272143 @default.
• W4294927214 hasLocation W42949272144 @default.
• W4294927214 hasOpenAccess W4294927214 @default.
• W4294927214 hasPrimaryLocation W42949272141 @default.
• W4294927214 hasRelatedWork W2003938723 @default.
• W4294927214 hasRelatedWork W2047967234 @default.
• W4294927214 hasRelatedWork W2118496982 @default.
• W4294927214 hasRelatedWork W2375344515 @default.
• W4294927214 hasRelatedWork W2439875401 @default.
• W4294927214 hasRelatedWork W3013366005 @default.
• W4294927214 hasRelatedWork W3082669180 @default.
• W4294927214 hasRelatedWork W4238867864 @default.
• W4294927214 hasRelatedWork W4313417088 @default.
• W4294927214 hasRelatedWork W2525756941 @default.
• W4294927214 hasVolume "12" @default.
• W4294927214 isParatext "false" @default.
• W4294927214 isRetracted "false" @default.
• W4294927214 workType "article" @default.