Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294940209> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4294940209 abstract "Aim: To investigate the application of anterior and posterior corneal higher order aberrations (HOAs) in detecting keratoconus (KC) and suspect keratoconus (SKC). Method: This is a retrospective, case-control study which evaluated non-ectatic (normal) eyes, SKC eyes, and KC eyes. The Sirius Scheimpfug (CSO, Italy) analyzer was used to measure HOAs of the anterior and posterior corneal surfaces. Sensitivity, specificity and area under receiver operating characteristic curve (AUC) were calculated. Results: Two-hundred and twenty eyes were included in the analysis (normal n = 108, SKC n= 42, KC n= 70). Receiver operating characteristic (ROC) curve analysis revealed a high predictive ability for anterior corneal HOAs parameters: Root mean square (RMS) total corneal HOAs, RMS trefoil and RMS coma to detect keratoconus (AUC > 0.9 for all). RMS Coma (3, ±1) derived from the anterior corneal surface was the parameter with the highest ability to discriminate between suspect keratoconus and normal eyes (AUC = 0.922; cutoff > 0.2). All posterior corneal HOAs parameters were insufficient in discriminating between SKC and normal eyes (AUC < 0.8 for all). In contrast, their ability to detect KC was excellent with AUC of > 0.9 for all except RMS spherical aberrations (AUC = 0.846). Conclusion: Anterior and posterior corneal higher order aberrations can differentiate between keratoconus and normal eyes, with a high level of certainty. In suspect keratoconus disease however, only anterior corneal HOAs, and in particular coma-like aberrations, are of value. Corneal aberrometry may be of value in screening for keratoconus in populations with a high prevalence of the disease." @default.
- W4294940209 created "2022-09-08" @default.
- W4294940209 creator A5044980888 @default.
- W4294940209 creator A5045798333 @default.
- W4294940209 creator A5051663157 @default.
- W4294940209 creator A5056613238 @default.
- W4294940209 creator A5065335992 @default.
- W4294940209 creator A5068132609 @default.
- W4294940209 creator A5070604004 @default.
- W4294940209 creator A5074758411 @default.
- W4294940209 date "2022-09-07" @default.
- W4294940209 modified "2023-10-08" @default.
- W4294940209 title "Evaluation of Anterior and Posterior Corneal Higher Order Aberrations for the Detection of Keratoconus and Suspect Keratoconus" @default.
- W4294940209 doi "https://doi.org/10.20944/preprints202209.0105.v1" @default.
- W4294940209 hasPublicationYear "2022" @default.
- W4294940209 type Work @default.
- W4294940209 citedByCount "0" @default.
- W4294940209 crossrefType "posted-content" @default.
- W4294940209 hasAuthorship W4294940209A5044980888 @default.
- W4294940209 hasAuthorship W4294940209A5045798333 @default.
- W4294940209 hasAuthorship W4294940209A5051663157 @default.
- W4294940209 hasAuthorship W4294940209A5056613238 @default.
- W4294940209 hasAuthorship W4294940209A5065335992 @default.
- W4294940209 hasAuthorship W4294940209A5068132609 @default.
- W4294940209 hasAuthorship W4294940209A5070604004 @default.
- W4294940209 hasAuthorship W4294940209A5074758411 @default.
- W4294940209 hasBestOaLocation W42949402091 @default.
- W4294940209 hasConcept C100136789 @default.
- W4294940209 hasConcept C118487528 @default.
- W4294940209 hasConcept C120665830 @default.
- W4294940209 hasConcept C121332964 @default.
- W4294940209 hasConcept C126322002 @default.
- W4294940209 hasConcept C165788157 @default.
- W4294940209 hasConcept C2776882836 @default.
- W4294940209 hasConcept C2778257484 @default.
- W4294940209 hasConcept C2778918178 @default.
- W4294940209 hasConcept C2781053140 @default.
- W4294940209 hasConcept C58471807 @default.
- W4294940209 hasConcept C71924100 @default.
- W4294940209 hasConcept C76318530 @default.
- W4294940209 hasConceptScore W4294940209C100136789 @default.
- W4294940209 hasConceptScore W4294940209C118487528 @default.
- W4294940209 hasConceptScore W4294940209C120665830 @default.
- W4294940209 hasConceptScore W4294940209C121332964 @default.
- W4294940209 hasConceptScore W4294940209C126322002 @default.
- W4294940209 hasConceptScore W4294940209C165788157 @default.
- W4294940209 hasConceptScore W4294940209C2776882836 @default.
- W4294940209 hasConceptScore W4294940209C2778257484 @default.
- W4294940209 hasConceptScore W4294940209C2778918178 @default.
- W4294940209 hasConceptScore W4294940209C2781053140 @default.
- W4294940209 hasConceptScore W4294940209C58471807 @default.
- W4294940209 hasConceptScore W4294940209C71924100 @default.
- W4294940209 hasConceptScore W4294940209C76318530 @default.
- W4294940209 hasLocation W42949402091 @default.
- W4294940209 hasLocation W42949402092 @default.
- W4294940209 hasLocation W42949402093 @default.
- W4294940209 hasLocation W42949402094 @default.
- W4294940209 hasOpenAccess W4294940209 @default.
- W4294940209 hasPrimaryLocation W42949402091 @default.
- W4294940209 hasRelatedWork W1843676142 @default.
- W4294940209 hasRelatedWork W2051159453 @default.
- W4294940209 hasRelatedWork W2107630979 @default.
- W4294940209 hasRelatedWork W2685607829 @default.
- W4294940209 hasRelatedWork W2743880820 @default.
- W4294940209 hasRelatedWork W3005410297 @default.
- W4294940209 hasRelatedWork W3194697196 @default.
- W4294940209 hasRelatedWork W4296807208 @default.
- W4294940209 hasRelatedWork W4312196577 @default.
- W4294940209 hasRelatedWork W2992544396 @default.
- W4294940209 isParatext "false" @default.
- W4294940209 isRetracted "false" @default.
- W4294940209 workType "article" @default.