FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294990813> ?p ?o ?g. }

• W4294990813 endingPage "596" @default.
• W4294990813 startingPage "583" @default.
• W4294990813 abstract "It has been 30 years since the first member of the protease-activated receptor (PAR) family was discovered. This was followed by the discovery of three other receptors, including PAR2. PAR2 is a G protein-coupled receptor activated by trypsin site-specific proteolysis. The process starts with serine proteases acting between arginine and serine, creating an N-terminus that functions as a tethered ligand that binds, after a conformational change, to the second extracellular loop of the receptor, leading to activation of G-proteins. The physiological and pathological functions of this ubiquitous receptor are still elusive. This review focuses on PAR2 activation and its distribution under physiological and pathological conditions, with a particular focus on the pancreas, a significant producer of trypsin, which is the prototype activator of the receptor. The role in acute or chronic pancreatitis, pancreatic cancer, and diabetes mellitus will be highlighted." @default.
• W4294990813 created "2022-09-09" @default.
• W4294990813 creator A5009344355 @default.
• W4294990813 creator A5018498515 @default.
• W4294990813 creator A5056763778 @default.
• W4294990813 date "2022-10-31" @default.
• W4294990813 modified "2023-10-03" @default.
• W4294990813 title "PAR2: The Cornerstone of Pancreatic Diseases" @default.
• W4294990813 cites W145763054 @default.
• W4294990813 cites W1495307817 @default.
• W4294990813 cites W1533133853 @default.
• W4294990813 cites W1567428067 @default.
• W4294990813 cites W158606542 @default.
• W4294990813 cites W1604394997 @default.
• W4294990813 cites W1812364192 @default.
• W4294990813 cites W1964499190 @default.
• W4294990813 cites W1965192419 @default.
• W4294990813 cites W1967309870 @default.
• W4294990813 cites W1972032648 @default.
• W4294990813 cites W1974907991 @default.
• W4294990813 cites W1978461355 @default.
• W4294990813 cites W1981029832 @default.
• W4294990813 cites W1982850112 @default.
• W4294990813 cites W1983544591 @default.
• W4294990813 cites W1985045980 @default.
• W4294990813 cites W1985110968 @default.
• W4294990813 cites W1986581361 @default.
• W4294990813 cites W1992073705 @default.
• W4294990813 cites W1992359712 @default.
• W4294990813 cites W1994103951 @default.
• W4294990813 cites W1994793711 @default.
• W4294990813 cites W1996139667 @default.
• W4294990813 cites W1999015815 @default.
• W4294990813 cites W1999548741 @default.
• W4294990813 cites W2006163097 @default.
• W4294990813 cites W2019361592 @default.
• W4294990813 cites W2027206331 @default.
• W4294990813 cites W2030079229 @default.
• W4294990813 cites W2031843235 @default.
• W4294990813 cites W2036468924 @default.
• W4294990813 cites W2043526402 @default.
• W4294990813 cites W2044067201 @default.
• W4294990813 cites W2044347636 @default.
• W4294990813 cites W2047594542 @default.
• W4294990813 cites W2053849474 @default.
• W4294990813 cites W2055319676 @default.
• W4294990813 cites W2056218137 @default.
• W4294990813 cites W2057361172 @default.
• W4294990813 cites W2069250255 @default.
• W4294990813 cites W2069755168 @default.
• W4294990813 cites W2070461974 @default.
• W4294990813 cites W2073664977 @default.
• W4294990813 cites W2081600999 @default.
• W4294990813 cites W2081753893 @default.
• W4294990813 cites W2087830435 @default.
• W4294990813 cites W2093117751 @default.
• W4294990813 cites W2093951002 @default.
• W4294990813 cites W2094987029 @default.
• W4294990813 cites W2095078777 @default.
• W4294990813 cites W2095155842 @default.
• W4294990813 cites W2105952767 @default.
• W4294990813 cites W2113564677 @default.
• W4294990813 cites W2114825960 @default.
• W4294990813 cites W2129559551 @default.
• W4294990813 cites W2135608710 @default.
• W4294990813 cites W2145218316 @default.
• W4294990813 cites W2146641981 @default.
• W4294990813 cites W2150546831 @default.
• W4294990813 cites W2150751346 @default.
• W4294990813 cites W2156709540 @default.
• W4294990813 cites W2157395235 @default.
• W4294990813 cites W2159231976 @default.
• W4294990813 cites W2165144161 @default.
• W4294990813 cites W2167547115 @default.
• W4294990813 cites W2168168058 @default.
• W4294990813 cites W2187108488 @default.
• W4294990813 cites W2289439614 @default.
• W4294990813 cites W2314042652 @default.
• W4294990813 cites W2337814907 @default.
• W4294990813 cites W2344875199 @default.
• W4294990813 cites W2418369814 @default.
• W4294990813 cites W2431396139 @default.
• W4294990813 cites W2473971994 @default.
• W4294990813 cites W2520432709 @default.
• W4294990813 cites W2531714473 @default.
• W4294990813 cites W2548604675 @default.
• W4294990813 cites W2554987853 @default.
• W4294990813 cites W2586440279 @default.
• W4294990813 cites W2609731092 @default.
• W4294990813 cites W2727485857 @default.
• W4294990813 cites W2794113061 @default.
• W4294990813 cites W2794487289 @default.
• W4294990813 cites W2799484952 @default.
• W4294990813 cites W2893209019 @default.
• W4294990813 cites W2913812850 @default.
• W4294990813 cites W2938073552 @default.
• W4294990813 cites W2941882132 @default.
• W4294990813 cites W2972661346 @default.

• next