FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294991818> ?p ?o ?g. }

• W4294991818 endingPage "563" @default.
• W4294991818 startingPage "557" @default.
• W4294991818 abstract "To study the clinico-radiological paradox in multiple sclerosis (MS) relapse by analyzing the number and location of gadolinium-enhanced (Gd+) lesions on brain MRI before methylprednisolone (MP) treatment.We analyzed brain MRI from 90 relapsed MS patients in two Phase IV multicenter double-blind randomized clinical trials that showed the noninferiority of different routes and doses of MP administration. A 1.5- or 3-T brain MRI was performed at baseline before MP treatment and within 15 days of symptom onset. The number and location of Gd+ lesions were analyzed. Associations were studied using univariate analysis.Sixty-two percent of patients had at least 1 Gd+ brain lesion; the median number was 1 (interquartile range 0-4), and 41% of patients had 2 or more lesions. The most frequent location of Gd+ lesions was subcortical (41.4%). Gd+ brain lesions were found in 71.4% of patients with brainstem-cerebellum symptoms, 57.1% with spinal cord symptoms and 55.5% with optic neuritis (ON). Thirty percent of patients with brain symptoms did not have Gd+ lesions, and only 43.6% of patients had symptomatic Gd+ lesions. The univariate analysis showed a negative correlation between age and the number of Gd+ lesions (p=0.002).Most patients with relapse showed several Gd+ lesions on brain MRI, even when the clinical manifestation was outside of the brain. Our findings illustrate the clinico-radiological paradox in MS relapse and support the value of brain MRI in this scenario." @default.
• W4294991818 created "2022-09-09" @default.
• W4294991818 creator A5007242200 @default.
• W4294991818 creator A5008318232 @default.
• W4294991818 creator A5008963944 @default.
• W4294991818 creator A5012005229 @default.
• W4294991818 creator A5014149554 @default.
• W4294991818 creator A5020674239 @default.
• W4294991818 creator A5023384534 @default.
• W4294991818 creator A5024893629 @default.
• W4294991818 creator A5026141567 @default.
• W4294991818 creator A5026966625 @default.
• W4294991818 creator A5045203220 @default.
• W4294991818 creator A5052019860 @default.
• W4294991818 creator A5061766796 @default.
• W4294991818 creator A5063275381 @default.
• W4294991818 creator A5078566505 @default.
• W4294991818 creator A5082890627 @default.
• W4294991818 date "2022-09-01" @default.
• W4294991818 modified "2023-10-18" @default.
• W4294991818 title "Gadolinium-enhanced brain lesions in multiple sclerosis relapse" @default.
• W4294991818 cites W1567125068 @default.
• W4294991818 cites W1763205699 @default.
• W4294991818 cites W1862026185 @default.
• W4294991818 cites W1993470842 @default.
• W4294991818 cites W2006322519 @default.
• W4294991818 cites W2024561693 @default.
• W4294991818 cites W2046748764 @default.
• W4294991818 cites W2058674452 @default.
• W4294991818 cites W2078315241 @default.
• W4294991818 cites W2094054210 @default.
• W4294991818 cites W2118277450 @default.
• W4294991818 cites W2127570501 @default.
• W4294991818 cites W2140036864 @default.
• W4294991818 cites W2141466262 @default.
• W4294991818 cites W2169262628 @default.
• W4294991818 cites W2172299842 @default.
• W4294991818 cites W2325038063 @default.
• W4294991818 cites W2329592563 @default.
• W4294991818 cites W2600162559 @default.
• W4294991818 cites W2761726403 @default.
• W4294991818 cites W2777074421 @default.
• W4294991818 cites W2895875365 @default.
• W4294991818 cites W3171747481 @default.
• W4294991818 cites W3187939800 @default.
• W4294991818 doi "https://doi.org/10.1016/j.nrleng.2021.10.005" @default.
• W4294991818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36064284" @default.
• W4294991818 hasPublicationYear "2022" @default.
• W4294991818 type Work @default.
• W4294991818 citedByCount "1" @default.
• W4294991818 countsByYear W42949918182023 @default.
• W4294991818 crossrefType "journal-article" @default.
• W4294991818 hasAuthorship W4294991818A5007242200 @default.
• W4294991818 hasAuthorship W4294991818A5008318232 @default.
• W4294991818 hasAuthorship W4294991818A5008963944 @default.
• W4294991818 hasAuthorship W4294991818A5012005229 @default.
• W4294991818 hasAuthorship W4294991818A5014149554 @default.
• W4294991818 hasAuthorship W4294991818A5020674239 @default.
• W4294991818 hasAuthorship W4294991818A5023384534 @default.
• W4294991818 hasAuthorship W4294991818A5024893629 @default.
• W4294991818 hasAuthorship W4294991818A5026141567 @default.
• W4294991818 hasAuthorship W4294991818A5026966625 @default.
• W4294991818 hasAuthorship W4294991818A5045203220 @default.
• W4294991818 hasAuthorship W4294991818A5052019860 @default.
• W4294991818 hasAuthorship W4294991818A5061766796 @default.
• W4294991818 hasAuthorship W4294991818A5063275381 @default.
• W4294991818 hasAuthorship W4294991818A5078566505 @default.
• W4294991818 hasAuthorship W4294991818A5082890627 @default.
• W4294991818 hasBestOaLocation W42949918181 @default.
• W4294991818 hasConcept C118552586 @default.
• W4294991818 hasConcept C119060515 @default.
• W4294991818 hasConcept C126322002 @default.
• W4294991818 hasConcept C126838900 @default.
• W4294991818 hasConcept C142724271 @default.
• W4294991818 hasConcept C143409427 @default.
• W4294991818 hasConcept C187382586 @default.
• W4294991818 hasConcept C2780640218 @default.
• W4294991818 hasConcept C2780775167 @default.
• W4294991818 hasConcept C2781156865 @default.
• W4294991818 hasConcept C2989005 @default.
• W4294991818 hasConcept C71924100 @default.
• W4294991818 hasConceptScore W4294991818C118552586 @default.
• W4294991818 hasConceptScore W4294991818C119060515 @default.
• W4294991818 hasConceptScore W4294991818C126322002 @default.
• W4294991818 hasConceptScore W4294991818C126838900 @default.
• W4294991818 hasConceptScore W4294991818C142724271 @default.
• W4294991818 hasConceptScore W4294991818C143409427 @default.
• W4294991818 hasConceptScore W4294991818C187382586 @default.
• W4294991818 hasConceptScore W4294991818C2780640218 @default.
• W4294991818 hasConceptScore W4294991818C2780775167 @default.
• W4294991818 hasConceptScore W4294991818C2781156865 @default.
• W4294991818 hasConceptScore W4294991818C2989005 @default.
• W4294991818 hasConceptScore W4294991818C71924100 @default.
• W4294991818 hasIssue "7" @default.
• W4294991818 hasLocation W42949918181 @default.
• W4294991818 hasLocation W42949918182 @default.
• W4294991818 hasLocation W42949918183 @default.
• W4294991818 hasLocation W42949918184 @default.

• next