Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294992533> ?p ?o ?g. }
- W4294992533 endingPage "13159" @default.
- W4294992533 startingPage "13152" @default.
- W4294992533 abstract "The growing concern about antibiotic-resistant microorganisms has focused on the sludge from wastewater treatment plants (WWTPs) as a potential hotspot for their development and spread. To this end, it seems relevant to analyze the changes on the microbiota as a consequence of the antibiotics that wastewater may contain. This study aims at determining whether the presence of sulfamethoxazole (SMX), even in relatively low concentrations, modifies the microbial activities and the enzymatic expression of an activated sludge under aerobic heterotrophic conditions. For that purpose, we applied a metaproteomic approach in combination with genomic and transformation product analyses. SMX was biotransformed, and the metabolite 2,4(1H,3H)-pteridinedione-SMX (PtO-SMX) from the pterin-conjugation pathway was detected at all concentrations tested. Metaproteomics showed that SMX at 50–2000 μg/L slightly affected the microbial community structure, which was confirmed by DNA metabarcoding. Interestingly, an enhanced activity of the genus Corynebacterium and specifically of five enzymes involved in its central carbon metabolism was found at increased SMX concentrations. Our results suggest a role of Corynebacterium genus on SMX risks mitigation in our bioreactors." @default.
- W4294992533 created "2022-09-09" @default.
- W4294992533 creator A5000865490 @default.
- W4294992533 creator A5025155680 @default.
- W4294992533 creator A5026947001 @default.
- W4294992533 creator A5031288803 @default.
- W4294992533 creator A5056502171 @default.
- W4294992533 creator A5079744056 @default.
- W4294992533 date "2022-09-08" @default.
- W4294992533 modified "2023-10-18" @default.
- W4294992533 title "Sulfamethoxazole Enhances Specific Enzymatic Activities under Aerobic Heterotrophic Conditions: A Metaproteomic Approach" @default.
- W4294992533 cites W1915220722 @default.
- W4294992533 cites W1936081875 @default.
- W4294992533 cites W1950654622 @default.
- W4294992533 cites W1971887998 @default.
- W4294992533 cites W1978101088 @default.
- W4294992533 cites W2007546590 @default.
- W4294992533 cites W2016115086 @default.
- W4294992533 cites W2020551149 @default.
- W4294992533 cites W2023409152 @default.
- W4294992533 cites W2027426520 @default.
- W4294992533 cites W2052059415 @default.
- W4294992533 cites W2052835842 @default.
- W4294992533 cites W2075350195 @default.
- W4294992533 cites W2087481305 @default.
- W4294992533 cites W2102627623 @default.
- W4294992533 cites W2103309978 @default.
- W4294992533 cites W2114766231 @default.
- W4294992533 cites W2128097826 @default.
- W4294992533 cites W2130334511 @default.
- W4294992533 cites W2287748332 @default.
- W4294992533 cites W2316746737 @default.
- W4294992533 cites W2331785775 @default.
- W4294992533 cites W2399912740 @default.
- W4294992533 cites W2470345072 @default.
- W4294992533 cites W2492711527 @default.
- W4294992533 cites W2593928043 @default.
- W4294992533 cites W2766521970 @default.
- W4294992533 cites W2792969127 @default.
- W4294992533 cites W2799861636 @default.
- W4294992533 cites W2804591757 @default.
- W4294992533 cites W2883455341 @default.
- W4294992533 cites W2891227781 @default.
- W4294992533 cites W2897722538 @default.
- W4294992533 cites W2899760200 @default.
- W4294992533 cites W2912801691 @default.
- W4294992533 cites W2944475069 @default.
- W4294992533 cites W2950438666 @default.
- W4294992533 cites W2963285166 @default.
- W4294992533 cites W2967441709 @default.
- W4294992533 cites W2969558030 @default.
- W4294992533 cites W3008788133 @default.
- W4294992533 cites W3010510295 @default.
- W4294992533 cites W3011309407 @default.
- W4294992533 cites W3045212395 @default.
- W4294992533 cites W3095842159 @default.
- W4294992533 cites W3098557317 @default.
- W4294992533 cites W3182578470 @default.
- W4294992533 cites W3214428373 @default.
- W4294992533 cites W4225700116 @default.
- W4294992533 cites W4246270606 @default.
- W4294992533 cites W639746973 @default.
- W4294992533 doi "https://doi.org/10.1021/acs.est.2c05001" @default.
- W4294992533 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36073795" @default.
- W4294992533 hasPublicationYear "2022" @default.
- W4294992533 type Work @default.
- W4294992533 citedByCount "6" @default.
- W4294992533 countsByYear W42949925332023 @default.
- W4294992533 crossrefType "journal-article" @default.
- W4294992533 hasAuthorship W4294992533A5000865490 @default.
- W4294992533 hasAuthorship W4294992533A5025155680 @default.
- W4294992533 hasAuthorship W4294992533A5026947001 @default.
- W4294992533 hasAuthorship W4294992533A5031288803 @default.
- W4294992533 hasAuthorship W4294992533A5056502171 @default.
- W4294992533 hasAuthorship W4294992533A5079744056 @default.
- W4294992533 hasBestOaLocation W42949925331 @default.
- W4294992533 hasConcept C104317684 @default.
- W4294992533 hasConcept C127413603 @default.
- W4294992533 hasConcept C15151743 @default.
- W4294992533 hasConcept C175605896 @default.
- W4294992533 hasConcept C185592680 @default.
- W4294992533 hasConcept C199465337 @default.
- W4294992533 hasConcept C2777730692 @default.
- W4294992533 hasConcept C31903555 @default.
- W4294992533 hasConcept C35195898 @default.
- W4294992533 hasConcept C523546767 @default.
- W4294992533 hasConcept C54355233 @default.
- W4294992533 hasConcept C55493867 @default.
- W4294992533 hasConcept C57442070 @default.
- W4294992533 hasConcept C81407943 @default.
- W4294992533 hasConcept C86803240 @default.
- W4294992533 hasConcept C87717796 @default.
- W4294992533 hasConcept C89423630 @default.
- W4294992533 hasConceptScore W4294992533C104317684 @default.
- W4294992533 hasConceptScore W4294992533C127413603 @default.
- W4294992533 hasConceptScore W4294992533C15151743 @default.
- W4294992533 hasConceptScore W4294992533C175605896 @default.
- W4294992533 hasConceptScore W4294992533C185592680 @default.