FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295015422> ?p ?o ?g. }

• W4295015422 endingPage "463473" @default.
• W4295015422 startingPage "463473" @default.
• W4295015422 abstract "Analysis of diastereomers of phosphorothioate oligonucleotides in ion-pairing reversed-phase liquid chromatography is affected not only by the character and concentration of ion-pairing system, but also by the separation temperature. In this work, eight ion-pairing systems at two concentrations buffered with acetic acid were used with octadecyl column to investigate the effects of temperature (in the range from 20 °C to 90 °C) on retention, diastereomeric separation, resolution of mers of different length and resolution of oligonucleotides with different number of phosphorothioate linkages. It was observed that elevated temperature suppresses the diastereomeric separation and oligonucleotide peaks become narrower. This improves the resolution of n and n-1 mers at elevated temperature. Plots of ln k (k = retention factor) versus reciprocal absolute temperature show that for 100 mM ion-pairing systems the increase in temperature does not lead to simple decrease in oligonucleotides retention as generally observed in reversed-phase liquid chromatography. The aim of this work is to improve chromatographic method for analysis of phosphorothioate oligonucleotides." @default.
• W4295015422 created "2022-09-09" @default.
• W4295015422 creator A5056898153 @default.
• W4295015422 creator A5073328989 @default.
• W4295015422 creator A5081316456 @default.
• W4295015422 creator A5084262635 @default.
• W4295015422 date "2022-10-01" @default.
• W4295015422 modified "2023-09-24" @default.
• W4295015422 title "Phosphorothioate oligonucleotides separation in ion-pairing reversed-phase liquid chromatography: effect of temperature" @default.
• W4295015422 cites W1940201797 @default.
• W4295015422 cites W1969061939 @default.
• W4295015422 cites W1977223522 @default.
• W4295015422 cites W1996313751 @default.
• W4295015422 cites W2023352786 @default.
• W4295015422 cites W2039780381 @default.
• W4295015422 cites W2051973766 @default.
• W4295015422 cites W2061687494 @default.
• W4295015422 cites W2075021096 @default.
• W4295015422 cites W2075310075 @default.
• W4295015422 cites W2080728136 @default.
• W4295015422 cites W2110166379 @default.
• W4295015422 cites W2124141386 @default.
• W4295015422 cites W2586216619 @default.
• W4295015422 cites W2739969651 @default.
• W4295015422 cites W2797978148 @default.
• W4295015422 cites W2898106004 @default.
• W4295015422 cites W2941475267 @default.
• W4295015422 cites W2992970519 @default.
• W4295015422 cites W3000940362 @default.
• W4295015422 cites W3157844628 @default.
• W4295015422 cites W3165513677 @default.
• W4295015422 cites W4210280799 @default.
• W4295015422 cites W4281955860 @default.
• W4295015422 doi "https://doi.org/10.1016/j.chroma.2022.463473" @default.
• W4295015422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36113338" @default.
• W4295015422 hasPublicationYear "2022" @default.
• W4295015422 type Work @default.
• W4295015422 citedByCount "3" @default.
• W4295015422 countsByYear W42950154222023 @default.
• W4295015422 crossrefType "journal-article" @default.
• W4295015422 hasAuthorship W4295015422A5056898153 @default.
• W4295015422 hasAuthorship W4295015422A5073328989 @default.
• W4295015422 hasAuthorship W4295015422A5081316456 @default.
• W4295015422 hasAuthorship W4295015422A5084262635 @default.
• W4295015422 hasConcept C113196181 @default.
• W4295015422 hasConcept C121332964 @default.
• W4295015422 hasConcept C129312508 @default.
• W4295015422 hasConcept C138268822 @default.
• W4295015422 hasConcept C138716334 @default.
• W4295015422 hasConcept C14103023 @default.
• W4295015422 hasConcept C154945302 @default.
• W4295015422 hasConcept C178790620 @default.
• W4295015422 hasConcept C179998833 @default.
• W4295015422 hasConcept C185592680 @default.
• W4295015422 hasConcept C41008148 @default.
• W4295015422 hasConcept C43617362 @default.
• W4295015422 hasConcept C44280652 @default.
• W4295015422 hasConcept C45188465 @default.
• W4295015422 hasConcept C51724486 @default.
• W4295015422 hasConcept C54101563 @default.
• W4295015422 hasConcept C552990157 @default.
• W4295015422 hasConcept C55493867 @default.
• W4295015422 hasConcept C62520636 @default.
• W4295015422 hasConcept C71240020 @default.
• W4295015422 hasConceptScore W4295015422C113196181 @default.
• W4295015422 hasConceptScore W4295015422C121332964 @default.
• W4295015422 hasConceptScore W4295015422C129312508 @default.
• W4295015422 hasConceptScore W4295015422C138268822 @default.
• W4295015422 hasConceptScore W4295015422C138716334 @default.
• W4295015422 hasConceptScore W4295015422C14103023 @default.
• W4295015422 hasConceptScore W4295015422C154945302 @default.
• W4295015422 hasConceptScore W4295015422C178790620 @default.
• W4295015422 hasConceptScore W4295015422C179998833 @default.
• W4295015422 hasConceptScore W4295015422C185592680 @default.
• W4295015422 hasConceptScore W4295015422C41008148 @default.
• W4295015422 hasConceptScore W4295015422C43617362 @default.
• W4295015422 hasConceptScore W4295015422C44280652 @default.
• W4295015422 hasConceptScore W4295015422C45188465 @default.
• W4295015422 hasConceptScore W4295015422C51724486 @default.
• W4295015422 hasConceptScore W4295015422C54101563 @default.
• W4295015422 hasConceptScore W4295015422C552990157 @default.
• W4295015422 hasConceptScore W4295015422C55493867 @default.
• W4295015422 hasConceptScore W4295015422C62520636 @default.
• W4295015422 hasConceptScore W4295015422C71240020 @default.
• W4295015422 hasFunder F4320321006 @default.
• W4295015422 hasLocation W42950154221 @default.
• W4295015422 hasLocation W42950154222 @default.
• W4295015422 hasOpenAccess W4295015422 @default.
• W4295015422 hasPrimaryLocation W42950154221 @default.
• W4295015422 hasRelatedWork W1973255245 @default.
• W4295015422 hasRelatedWork W1976607297 @default.
• W4295015422 hasRelatedWork W1979592700 @default.
• W4295015422 hasRelatedWork W2039531209 @default.
• W4295015422 hasRelatedWork W2041681806 @default.
• W4295015422 hasRelatedWork W2045532927 @default.
• W4295015422 hasRelatedWork W2065647693 @default.
• W4295015422 hasRelatedWork W2065894166 @default.
• W4295015422 hasRelatedWork W4255185366 @default.

• next