Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295037632> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4295037632 endingPage "1445" @default.
- W4295037632 startingPage "1440" @default.
- W4295037632 abstract "Abstract This study aimed to conduct a detailed study on murine model testing of bacteriophage against Acinetobacter baumannii . These bacteriophages were tested not only for their efficacy in healing wound of murine models infected with multidrug resistant A. baumannii but were also studied for any derangement in hematological parameters as well as liver and kidney function. The study also included any histological changes observed in hepatic and renal tissues of the bacteriophage treated murine animals. This experimental study was conducted at Institute of Basic Medical Sciences, Khyber Medical University, Peshawar and Institute of Pure and Applied Biology, Department of Microbiology and Molecular Genetics, Bahauddin Zakariya University, Multan. A. baumannii isolates were obtained from the Microbiology Department, Armed Forces Institute of Pathology, Rawalpindi. Antimicrobial susceptibility was done by using standard procedures and as per Clinical Laboratory Standards Institute guidelines. Bacteriophages were isolated from sewage water samples collected from different hospitals in Multan. These bacteriophages were characterized and finally used for treating the murine model and efficacy of phage as a therapeutic option was determined by using superficial rat wound model. In this study, the isolated lytic bacteriophage was effective in relatively faster wound healing of the infected animals. Moreover, there were no significant hematological or renal and hepatic profile changes in treated animals. Histology of renal and hepatic tissues was also normal as compared to control animals. Our study concluded that the isolated phage could serve as an attractive therapeutic candidate to combat the deadly multidrug resistant A. baumannii ." @default.
- W4295037632 created "2022-09-09" @default.
- W4295037632 creator A5001512805 @default.
- W4295037632 creator A5003891701 @default.
- W4295037632 creator A5004742106 @default.
- W4295037632 date "2022-09-09" @default.
- W4295037632 modified "2023-09-26" @default.
- W4295037632 title "Animal model testing for efficacy and adverse effects of bacteriophages against <i>Acinetobacter baumannii</i>" @default.
- W4295037632 cites W1974394752 @default.
- W4295037632 cites W2103084226 @default.
- W4295037632 cites W2109442030 @default.
- W4295037632 cites W2502279078 @default.
- W4295037632 cites W2528872419 @default.
- W4295037632 cites W2777989883 @default.
- W4295037632 cites W2790853404 @default.
- W4295037632 cites W2890653912 @default.
- W4295037632 cites W2909648129 @default.
- W4295037632 cites W2945461124 @default.
- W4295037632 cites W4255578408 @default.
- W4295037632 doi "https://doi.org/10.1002/jobm.202200288" @default.
- W4295037632 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36084216" @default.
- W4295037632 hasPublicationYear "2022" @default.
- W4295037632 type Work @default.
- W4295037632 citedByCount "0" @default.
- W4295037632 crossrefType "journal-article" @default.
- W4295037632 hasAuthorship W4295037632A5001512805 @default.
- W4295037632 hasAuthorship W4295037632A5003891701 @default.
- W4295037632 hasAuthorship W4295037632A5004742106 @default.
- W4295037632 hasConcept C104317684 @default.
- W4295037632 hasConcept C159047783 @default.
- W4295037632 hasConcept C182615771 @default.
- W4295037632 hasConcept C2522874641 @default.
- W4295037632 hasConcept C2776315533 @default.
- W4295037632 hasConcept C2776441376 @default.
- W4295037632 hasConcept C2777637488 @default.
- W4295037632 hasConcept C2779256223 @default.
- W4295037632 hasConcept C4937899 @default.
- W4295037632 hasConcept C523546767 @default.
- W4295037632 hasConcept C54355233 @default.
- W4295037632 hasConcept C547475151 @default.
- W4295037632 hasConcept C55493867 @default.
- W4295037632 hasConcept C71924100 @default.
- W4295037632 hasConcept C86803240 @default.
- W4295037632 hasConcept C89423630 @default.
- W4295037632 hasConceptScore W4295037632C104317684 @default.
- W4295037632 hasConceptScore W4295037632C159047783 @default.
- W4295037632 hasConceptScore W4295037632C182615771 @default.
- W4295037632 hasConceptScore W4295037632C2522874641 @default.
- W4295037632 hasConceptScore W4295037632C2776315533 @default.
- W4295037632 hasConceptScore W4295037632C2776441376 @default.
- W4295037632 hasConceptScore W4295037632C2777637488 @default.
- W4295037632 hasConceptScore W4295037632C2779256223 @default.
- W4295037632 hasConceptScore W4295037632C4937899 @default.
- W4295037632 hasConceptScore W4295037632C523546767 @default.
- W4295037632 hasConceptScore W4295037632C54355233 @default.
- W4295037632 hasConceptScore W4295037632C547475151 @default.
- W4295037632 hasConceptScore W4295037632C55493867 @default.
- W4295037632 hasConceptScore W4295037632C71924100 @default.
- W4295037632 hasConceptScore W4295037632C86803240 @default.
- W4295037632 hasConceptScore W4295037632C89423630 @default.
- W4295037632 hasIssue "12" @default.
- W4295037632 hasLocation W42950376321 @default.
- W4295037632 hasLocation W42950376322 @default.
- W4295037632 hasOpenAccess W4295037632 @default.
- W4295037632 hasPrimaryLocation W42950376321 @default.
- W4295037632 hasRelatedWork W2909648129 @default.
- W4295037632 hasRelatedWork W2943705526 @default.
- W4295037632 hasRelatedWork W4281772394 @default.
- W4295037632 hasRelatedWork W4282981431 @default.
- W4295037632 hasRelatedWork W4283720103 @default.
- W4295037632 hasRelatedWork W4307243765 @default.
- W4295037632 hasRelatedWork W4307942366 @default.
- W4295037632 hasRelatedWork W4309625980 @default.
- W4295037632 hasRelatedWork W4316464921 @default.
- W4295037632 hasRelatedWork W4385477214 @default.
- W4295037632 hasVolume "62" @default.
- W4295037632 isParatext "false" @default.
- W4295037632 isRetracted "false" @default.
- W4295037632 workType "article" @default.