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- W4295132224 endingPage "32907" @default.
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- W4295132224 abstract "Affinity chromatography is a well-known method dependent on molecular recognition and is used to purify biomolecules by mimicking the specific interactions between the biomolecules and their substrates. Enzyme substrates, cofactors, antigens, and inhibitors are generally utilized as bioligands in affinity chromatography. However, their cost, instability, and leakage problems are the main drawbacks of these bioligands. Biomimetic affinity ligands can recognize their target molecules with high selectivity. Their cost-effectiveness and chemical and biological stabilities make these antibody analogs favorable candidates for affinity chromatography applications. Biomimetics applies to nature and aims to develop nanodevices, processes, and nanomaterials. Today, biomimetics provides a design approach to the biomimetic affinity ligands with the aid of computational methods, rational design, and other approaches to meet the requirements of the bioligands and improve the downstream process. This review highlighted the recent trends in designing biomimetic affinity ligands and summarized their binding interactions with the target molecules with computational approaches." @default.
- W4295132224 created "2022-09-11" @default.
- W4295132224 creator A5000831004 @default.
- W4295132224 creator A5037319265 @default.
- W4295132224 creator A5053663464 @default.
- W4295132224 creator A5062737844 @default.
- W4295132224 creator A5060673406 @default.
- W4295132224 date "2022-09-09" @default.
- W4295132224 modified "2023-10-18" @default.
- W4295132224 title "Inspirations of Biomimetic Affinity Ligands: A Review" @default.
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