Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295222527> ?p ?o ?g. }
- W4295222527 endingPage "26" @default.
- W4295222527 startingPage "19" @default.
- W4295222527 abstract "Canine morbillivirus is a highly contagious multi-host pathogen with high morbidity and mortality. Timely diagnosis is of utmost importance to effectively control such a dreadful disease. Monoclonal antibodies (mAbs) serve as a high throughput diagnostics and applied tools for research and development (R&D). In the present study, a total of six mouse monoclonal antibodies were developed. All the mAbs generated belonged to IgG class. Of the six mAbs, two of them, namely CD-2F8 and CD-3D8 were directed against the nucleocapsid protein of CDV as determined in western blotting. The reactivity of all the mAbs was checked in indirect-ELISA and cell-ELISA using different morbilliviruses. The mAbs could broadly be categorized as; CDV specific (CD-3D8 and CD-2F8), cross-reactive to PPR virus (CD-AB3 and CD-4D6) and cross-reactive to both PPR virus and measles virus (CD-5D10 and CD-6E5). The characterized mAbs were used for antigenic profiling of CDV, PPR virus and measles virus. Based on the reactivity pattern; a close antigenic relationship was found among CDV and PPR virus as compared to measles virus. A pair of CDV specific mAbs namely CD-2F8 and CD-3D8 were identified which did not cross-react with measles and PPR viruses and thus could be used for diagnostic applications." @default.
- W4295222527 created "2022-09-12" @default.
- W4295222527 creator A5021572154 @default.
- W4295222527 creator A5024012453 @default.
- W4295222527 creator A5044485488 @default.
- W4295222527 creator A5070806510 @default.
- W4295222527 creator A5082202341 @default.
- W4295222527 creator A5085484066 @default.
- W4295222527 creator A5089978008 @default.
- W4295222527 creator A5091721671 @default.
- W4295222527 date "2022-09-01" @default.
- W4295222527 modified "2023-09-30" @default.
- W4295222527 title "Development and characterization of mouse monoclonal antibodies to canine morbillivirus" @default.
- W4295222527 cites W1489097369 @default.
- W4295222527 cites W1532024563 @default.
- W4295222527 cites W1533777667 @default.
- W4295222527 cites W1576100239 @default.
- W4295222527 cites W1582863396 @default.
- W4295222527 cites W1852337472 @default.
- W4295222527 cites W1967560157 @default.
- W4295222527 cites W1971755562 @default.
- W4295222527 cites W1972588822 @default.
- W4295222527 cites W1974067879 @default.
- W4295222527 cites W2001052062 @default.
- W4295222527 cites W2002730881 @default.
- W4295222527 cites W2006059758 @default.
- W4295222527 cites W2009063919 @default.
- W4295222527 cites W2021551034 @default.
- W4295222527 cites W2043080983 @default.
- W4295222527 cites W2046077509 @default.
- W4295222527 cites W2047016330 @default.
- W4295222527 cites W2059836405 @default.
- W4295222527 cites W2063644044 @default.
- W4295222527 cites W2072974435 @default.
- W4295222527 cites W2076141179 @default.
- W4295222527 cites W2115737875 @default.
- W4295222527 cites W2129509656 @default.
- W4295222527 cites W2150716315 @default.
- W4295222527 cites W2216761355 @default.
- W4295222527 cites W2334189555 @default.
- W4295222527 cites W2538483139 @default.
- W4295222527 cites W2571363236 @default.
- W4295222527 cites W2612302689 @default.
- W4295222527 cites W2768531046 @default.
- W4295222527 cites W2792565346 @default.
- W4295222527 cites W2888408992 @default.
- W4295222527 cites W2896528863 @default.
- W4295222527 cites W2911675607 @default.
- W4295222527 cites W2977766360 @default.
- W4295222527 cites W3007592031 @default.
- W4295222527 cites W3095771272 @default.
- W4295222527 doi "https://doi.org/10.1016/j.biologicals.2022.08.005" @default.
- W4295222527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36096853" @default.
- W4295222527 hasPublicationYear "2022" @default.
- W4295222527 type Work @default.
- W4295222527 citedByCount "2" @default.
- W4295222527 countsByYear W42952225272023 @default.
- W4295222527 crossrefType "journal-article" @default.
- W4295222527 hasAuthorship W4295222527A5021572154 @default.
- W4295222527 hasAuthorship W4295222527A5024012453 @default.
- W4295222527 hasAuthorship W4295222527A5044485488 @default.
- W4295222527 hasAuthorship W4295222527A5070806510 @default.
- W4295222527 hasAuthorship W4295222527A5082202341 @default.
- W4295222527 hasAuthorship W4295222527A5085484066 @default.
- W4295222527 hasAuthorship W4295222527A5089978008 @default.
- W4295222527 hasAuthorship W4295222527A5091721671 @default.
- W4295222527 hasConcept C147483822 @default.
- W4295222527 hasConcept C159047783 @default.
- W4295222527 hasConcept C159654299 @default.
- W4295222527 hasConcept C203014093 @default.
- W4295222527 hasConcept C22070199 @default.
- W4295222527 hasConcept C2522874641 @default.
- W4295222527 hasConcept C2776040883 @default.
- W4295222527 hasConcept C2776096392 @default.
- W4295222527 hasConcept C2776438120 @default.
- W4295222527 hasConcept C2778199166 @default.
- W4295222527 hasConcept C2780727368 @default.
- W4295222527 hasConcept C2780813555 @default.
- W4295222527 hasConcept C2910064783 @default.
- W4295222527 hasConcept C542903549 @default.
- W4295222527 hasConcept C86803240 @default.
- W4295222527 hasConceptScore W4295222527C147483822 @default.
- W4295222527 hasConceptScore W4295222527C159047783 @default.
- W4295222527 hasConceptScore W4295222527C159654299 @default.
- W4295222527 hasConceptScore W4295222527C203014093 @default.
- W4295222527 hasConceptScore W4295222527C22070199 @default.
- W4295222527 hasConceptScore W4295222527C2522874641 @default.
- W4295222527 hasConceptScore W4295222527C2776040883 @default.
- W4295222527 hasConceptScore W4295222527C2776096392 @default.
- W4295222527 hasConceptScore W4295222527C2776438120 @default.
- W4295222527 hasConceptScore W4295222527C2778199166 @default.
- W4295222527 hasConceptScore W4295222527C2780727368 @default.
- W4295222527 hasConceptScore W4295222527C2780813555 @default.
- W4295222527 hasConceptScore W4295222527C2910064783 @default.
- W4295222527 hasConceptScore W4295222527C542903549 @default.
- W4295222527 hasConceptScore W4295222527C86803240 @default.
- W4295222527 hasLocation W42952225271 @default.
- W4295222527 hasLocation W42952225272 @default.