FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295235087> ?p ?o ?g. }

• W4295235087 endingPage "780" @default.
• W4295235087 startingPage "769" @default.
• W4295235087 abstract "Abstract The poor prognosis of pancreatic ductal adenocarcinoma (PDAC) is mainly attributed to late diagnosis. We assessed the predictive performance of our previously reported urine biomarker panel for earlier detection of PDAC (LYVE1, REG1B and TFF1) in prediagnostic samples, alone and in combination with plasma CA19‐9. This nested case‐control study included 99 PDAC cases with urine samples prospectively collected up to 5 years prior to PDAC diagnosis and 198 matched controls. The samples were obtained from the Shanghai Women's Health Study (SWHS), the Shanghai Men's Health Studies (SMHS) and the Southern Community Cohort Study (SCCS). The urine biomarkers were measured by ELISA. Plasma CA19‐9 was quantified by Luminex. Multiple logistic regression and Wilcoxon rank‐sum and Mann‐Whitney test were used for analysis. The internal validation approach was applied and the validated AUC estimators are reported on. The algorithm of urinary protein panel, urine creatinine and age named PancRISK, displayed similar AUC as CA19‐9 up to 1 year before PDAC diagnosis (AUC = 0.79); however, the combination enhanced the AUCs to 0.89, and showed good discriminative ability (AUC = 0.77) up to 2 years. The combination showed sensitivity (SN) of 72% at 90% specificity (SP), and SP of 59% at 90% SN up to 1 year and 60% SN with 80% SP and 53% SP with 80% SN up to 2 years before PDAC diagnosis. Adding the clinical information on BMI value resulted in the overall improvement in performance of the PancRISK score. When combined with CA19‐9, the urinary panel reached a workable model for detecting PDAC cases up to 2 years prior to diagnosis." @default.
• W4295235087 created "2022-09-12" @default.
• W4295235087 creator A5005513706 @default.
• W4295235087 creator A5027435550 @default.
• W4295235087 creator A5038382199 @default.
• W4295235087 creator A5046487897 @default.
• W4295235087 creator A5049096725 @default.
• W4295235087 creator A5060498938 @default.
• W4295235087 creator A5071919754 @default.
• W4295235087 creator A5085657415 @default.
• W4295235087 creator A5090411791 @default.
• W4295235087 date "2022-09-23" @default.
• W4295235087 modified "2023-10-17" @default.
• W4295235087 title "Urine biomarkers enable pancreatic cancer detection up to 2 years before diagnosis" @default.
• W4295235087 cites W1825978543 @default.
• W4295235087 cites W1929411275 @default.
• W4295235087 cites W2016009254 @default.
• W4295235087 cites W2049901436 @default.
• W4295235087 cites W2064141899 @default.
• W4295235087 cites W2069376956 @default.
• W4295235087 cites W2070574237 @default.
• W4295235087 cites W2081468402 @default.
• W4295235087 cites W2086894535 @default.
• W4295235087 cites W2088819114 @default.
• W4295235087 cites W2107376767 @default.
• W4295235087 cites W2138427587 @default.
• W4295235087 cites W2143201275 @default.
• W4295235087 cites W2156250197 @default.
• W4295235087 cites W2159946871 @default.
• W4295235087 cites W2163459778 @default.
• W4295235087 cites W2167946477 @default.
• W4295235087 cites W2169816791 @default.
• W4295235087 cites W2172080880 @default.
• W4295235087 cites W2173639106 @default.
• W4295235087 cites W2298357652 @default.
• W4295235087 cites W2304258614 @default.
• W4295235087 cites W2328176404 @default.
• W4295235087 cites W2395563932 @default.
• W4295235087 cites W2555191434 @default.
• W4295235087 cites W2567341816 @default.
• W4295235087 cites W2604609431 @default.
• W4295235087 cites W2610732926 @default.
• W4295235087 cites W2748671548 @default.
• W4295235087 cites W2770675262 @default.
• W4295235087 cites W2782850612 @default.
• W4295235087 cites W2790015332 @default.
• W4295235087 cites W2800004611 @default.
• W4295235087 cites W2893101140 @default.
• W4295235087 cites W2970575819 @default.
• W4295235087 cites W2980120731 @default.
• W4295235087 cites W2992927504 @default.
• W4295235087 cites W2995984299 @default.
• W4295235087 cites W3006463783 @default.
• W4295235087 cites W3024754721 @default.
• W4295235087 cites W3089960846 @default.
• W4295235087 cites W3111000697 @default.
• W4295235087 cites W3165814576 @default.
• W4295235087 cites W4206841660 @default.
• W4295235087 cites W4295235087 @default.
• W4295235087 doi "https://doi.org/10.1002/ijc.34287" @default.
• W4295235087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36093581" @default.
• W4295235087 hasPublicationYear "2022" @default.
• W4295235087 type Work @default.
• W4295235087 citedByCount "7" @default.
• W4295235087 countsByYear W42952350872022 @default.
• W4295235087 countsByYear W42952350872023 @default.
• W4295235087 crossrefType "journal-article" @default.
• W4295235087 hasAuthorship W4295235087A5005513706 @default.
• W4295235087 hasAuthorship W4295235087A5027435550 @default.
• W4295235087 hasAuthorship W4295235087A5038382199 @default.
• W4295235087 hasAuthorship W4295235087A5046487897 @default.
• W4295235087 hasAuthorship W4295235087A5049096725 @default.
• W4295235087 hasAuthorship W4295235087A5060498938 @default.
• W4295235087 hasAuthorship W4295235087A5071919754 @default.
• W4295235087 hasAuthorship W4295235087A5085657415 @default.
• W4295235087 hasAuthorship W4295235087A5090411791 @default.
• W4295235087 hasBestOaLocation W42952350871 @default.
• W4295235087 hasConcept C121608353 @default.
• W4295235087 hasConcept C126322002 @default.
• W4295235087 hasConcept C143998085 @default.
• W4295235087 hasConcept C151956035 @default.
• W4295235087 hasConcept C2780026642 @default.
• W4295235087 hasConcept C2780210213 @default.
• W4295235087 hasConcept C2780306776 @default.
• W4295235087 hasConcept C2781197716 @default.
• W4295235087 hasConcept C55493867 @default.
• W4295235087 hasConcept C71924100 @default.
• W4295235087 hasConcept C72563966 @default.
• W4295235087 hasConcept C77411442 @default.
• W4295235087 hasConcept C86803240 @default.
• W4295235087 hasConcept C90924648 @default.
• W4295235087 hasConceptScore W4295235087C121608353 @default.
• W4295235087 hasConceptScore W4295235087C126322002 @default.
• W4295235087 hasConceptScore W4295235087C143998085 @default.
• W4295235087 hasConceptScore W4295235087C151956035 @default.
• W4295235087 hasConceptScore W4295235087C2780026642 @default.
• W4295235087 hasConceptScore W4295235087C2780210213 @default.
• W4295235087 hasConceptScore W4295235087C2780306776 @default.

• next