Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295339153> ?p ?o ?g. }
- W4295339153 endingPage "105127" @default.
- W4295339153 startingPage "105127" @default.
- W4295339153 abstract "Immunoengineering technologies harness the power of immune system modulators such as monoclonal antibodies, cytokines, and vaccines to treat myriad diseases. Immunoengineering innovations have showed great promise in various practices including oncology, infectious disease, autoimmune diseases, and transplantation. Despite the countless successes, the majority of immunoengineering products contain active moieties that are prone to instability. The current review aims to feature freeze-drying as a robust and scalable solution to the inherent stability challenges in immunoengineering products by preventing the active moiety from degradation. Furthermore, this review describes the stability issues related to immunoengineering products and the utility of the lyophilization process to preserve the integrity and efficacy of immunoengineering tools ranging from biologics to nanoparticle-based vaccines. The concept of the freeze-drying process is described highlighting the quality by design (QbD) for robust process optimization. Case studies of lyophilized immunoengineering technologies and relevant clinical studies using immunoengineering products are discussed." @default.
- W4295339153 created "2022-09-13" @default.
- W4295339153 creator A5024247051 @default.
- W4295339153 creator A5044395046 @default.
- W4295339153 creator A5044461726 @default.
- W4295339153 creator A5082820048 @default.
- W4295339153 date "2022-10-01" @default.
- W4295339153 modified "2023-09-26" @default.
- W4295339153 title "Freeze-drying for the preservation of immunoengineering products" @default.
- W4295339153 cites W1969097940 @default.
- W4295339153 cites W1969874653 @default.
- W4295339153 cites W1980818146 @default.
- W4295339153 cites W1985668850 @default.
- W4295339153 cites W1987205432 @default.
- W4295339153 cites W1990660301 @default.
- W4295339153 cites W1994046491 @default.
- W4295339153 cites W1999151633 @default.
- W4295339153 cites W2007369629 @default.
- W4295339153 cites W2015954921 @default.
- W4295339153 cites W2016861978 @default.
- W4295339153 cites W2019669516 @default.
- W4295339153 cites W2019902939 @default.
- W4295339153 cites W2020966657 @default.
- W4295339153 cites W2027738333 @default.
- W4295339153 cites W2034944780 @default.
- W4295339153 cites W2035645815 @default.
- W4295339153 cites W2038127901 @default.
- W4295339153 cites W2038864688 @default.
- W4295339153 cites W2044332466 @default.
- W4295339153 cites W2048199422 @default.
- W4295339153 cites W2052924325 @default.
- W4295339153 cites W2053727980 @default.
- W4295339153 cites W2055127900 @default.
- W4295339153 cites W2055589818 @default.
- W4295339153 cites W2057999495 @default.
- W4295339153 cites W2067848480 @default.
- W4295339153 cites W2075771522 @default.
- W4295339153 cites W2092279282 @default.
- W4295339153 cites W2094175565 @default.
- W4295339153 cites W2094334289 @default.
- W4295339153 cites W2102416146 @default.
- W4295339153 cites W2103464170 @default.
- W4295339153 cites W2106183630 @default.
- W4295339153 cites W2114190596 @default.
- W4295339153 cites W2122344923 @default.
- W4295339153 cites W2127519720 @default.
- W4295339153 cites W2130594874 @default.
- W4295339153 cites W2134625581 @default.
- W4295339153 cites W2142447995 @default.
- W4295339153 cites W2150411892 @default.
- W4295339153 cites W2172054121 @default.
- W4295339153 cites W2175608963 @default.
- W4295339153 cites W2198074726 @default.
- W4295339153 cites W2227353206 @default.
- W4295339153 cites W2285881370 @default.
- W4295339153 cites W2516083370 @default.
- W4295339153 cites W2553402145 @default.
- W4295339153 cites W2557130919 @default.
- W4295339153 cites W2559914583 @default.
- W4295339153 cites W2560774086 @default.
- W4295339153 cites W2568949398 @default.
- W4295339153 cites W2746360101 @default.
- W4295339153 cites W2748508681 @default.
- W4295339153 cites W2748992739 @default.
- W4295339153 cites W2765546463 @default.
- W4295339153 cites W2766958390 @default.
- W4295339153 cites W2768418205 @default.
- W4295339153 cites W2786139881 @default.
- W4295339153 cites W2791277363 @default.
- W4295339153 cites W2792358501 @default.
- W4295339153 cites W2792523566 @default.
- W4295339153 cites W2807864393 @default.
- W4295339153 cites W2826329248 @default.
- W4295339153 cites W2857500415 @default.
- W4295339153 cites W2888677649 @default.
- W4295339153 cites W2897177790 @default.
- W4295339153 cites W2907358011 @default.
- W4295339153 cites W2911318662 @default.
- W4295339153 cites W2912608563 @default.
- W4295339153 cites W2942091494 @default.
- W4295339153 cites W2944917458 @default.
- W4295339153 cites W2945798418 @default.
- W4295339153 cites W2953841148 @default.
- W4295339153 cites W2971940586 @default.
- W4295339153 cites W2980637141 @default.
- W4295339153 cites W2988103426 @default.
- W4295339153 cites W2990337693 @default.
- W4295339153 cites W2991834586 @default.
- W4295339153 cites W3005961874 @default.
- W4295339153 cites W3009492228 @default.
- W4295339153 cites W3011313923 @default.
- W4295339153 cites W3012055672 @default.
- W4295339153 cites W3014901343 @default.
- W4295339153 cites W3026778626 @default.
- W4295339153 cites W3034500342 @default.
- W4295339153 cites W3038006764 @default.
- W4295339153 cites W3047261279 @default.
- W4295339153 cites W3049408813 @default.