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- W4295422290 abstract "Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a rare and aggressive inflammatory myofibroblastic tumour (IMT) variant. This report identifies the first case of EIMS with leukemoid reaction. This is also the first case in which pancreatic infiltration occurred from the disease onset. A 14-year male patient presented with an 18×18×10 cm mass at the retroperitoneal space and a white blood cell (WBC) count of 85×109/L. The mass and the invaded tissues were surgically removed with tumour-free margins. Histopathology and bone marrow aspiration confirmed the diagnosis of EIMS with leukemoid reaction. The tumour recurred with hepatic and pulmonary metastasis one month after the surgery. WBC count also increased progressively with the tumour recurrence. There is no consensus on the treatment of EIMS. Since ALK rearrangement presents in all the EIMS cases, surgical resection combined with crizotinib or other targeted drugs may improve the prognosis. Key Words: Sarcoma, Soft tissue neoplasms, Leukemoid reaction, Crizotinib." @default.
- W4295422290 created "2022-09-14" @default.
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- W4295422290 date "2022-09-01" @default.
- W4295422290 modified "2023-10-14" @default.
- W4295422290 title "Epithelioid Inflammatory Myofibroblastic Sarcoma with Leukemoid Reaction" @default.
- W4295422290 doi "https://doi.org/10.29271/jcpsp.2022.09.1212" @default.
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