FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295476639> ?p ?o ?g. }

• W4295476639 endingPage "250" @default.
• W4295476639 startingPage "233" @default.
• W4295476639 abstract "CD4+ T cells play a vital role in the immune response, and their function requires T cell receptor (TCR) recognition of peptide epitopes presented in complex with MHC class II (MHCII) molecules. Consequently, rapidly identifying peptides that bind MHCII is critical to understanding and treating infectious disease, cancer, autoimmunity, allergy, and transplant rejection. Computational methods provide a fast, ultrahigh-throughput approach to predict MHCII-binding peptides but lack the accuracy of experimental methods. In contrast, experimental methods offer accurate, quantitative results at the expense of speed. To address the gap between these two approaches, we developed a high-throughput, semiquantitative experimental screening strategy termed microsphere-assisted peptide screening (MAPS). Here, we use the Zika virus envelope protein as an example to demonstrate the rapid identification of MHCII-binding peptides from a single pathogenic protein using MAPS. This process involves several key steps including peptide library design, peptide exchange into MHCII, peptide-MHCII loading onto microspheres, flow cytometry screening, and data analysis to identify peptides that bind to one or more MHCII alleles." @default.
• W4295476639 created "2022-09-14" @default.
• W4295476639 creator A5007347632 @default.
• W4295476639 creator A5028860077 @default.
• W4295476639 creator A5036332505 @default.
• W4295476639 date "2022-01-01" @default.
• W4295476639 modified "2023-10-14" @default.
• W4295476639 title "Rapid Identification of MHCII-Binding Peptides Through Microsphere-Assisted Peptide Screening (MAPS)" @default.
• W4295476639 cites W1839525253 @default.
• W4295476639 cites W1884857780 @default.
• W4295476639 cites W1913593355 @default.
• W4295476639 cites W1927635887 @default.
• W4295476639 cites W1977281284 @default.
• W4295476639 cites W2006167081 @default.
• W4295476639 cites W2029471237 @default.
• W4295476639 cites W2033654955 @default.
• W4295476639 cites W2076339383 @default.
• W4295476639 cites W2091808334 @default.
• W4295476639 cites W2129612249 @default.
• W4295476639 cites W2136066387 @default.
• W4295476639 cites W2137940095 @default.
• W4295476639 cites W2141805957 @default.
• W4295476639 cites W2143355289 @default.
• W4295476639 cites W2149350146 @default.
• W4295476639 cites W2160303218 @default.
• W4295476639 cites W2160794016 @default.
• W4295476639 cites W2165460177 @default.
• W4295476639 cites W2467471261 @default.
• W4295476639 cites W2480435167 @default.
• W4295476639 cites W2559077904 @default.
• W4295476639 cites W2728273554 @default.
• W4295476639 cites W2801389376 @default.
• W4295476639 cites W2813883312 @default.
• W4295476639 cites W2898389621 @default.
• W4295476639 cites W2949275735 @default.
• W4295476639 cites W2982242904 @default.
• W4295476639 cites W2987502822 @default.
• W4295476639 cites W2991064453 @default.
• W4295476639 cites W2999215541 @default.
• W4295476639 cites W3005844923 @default.
• W4295476639 cites W3037718428 @default.
• W4295476639 cites W3044770175 @default.
• W4295476639 cites W3097310171 @default.
• W4295476639 cites W3121008609 @default.
• W4295476639 cites W3121401640 @default.
• W4295476639 cites W3122458452 @default.
• W4295476639 cites W3124869717 @default.
• W4295476639 cites W3176578441 @default.
• W4295476639 doi "https://doi.org/10.1007/978-1-0716-2712-9_11" @default.
• W4295476639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36087205" @default.
• W4295476639 hasPublicationYear "2022" @default.
• W4295476639 type Work @default.
• W4295476639 citedByCount "0" @default.
• W4295476639 crossrefType "book-chapter" @default.
• W4295476639 hasAuthorship W4295476639A5007347632 @default.
• W4295476639 hasAuthorship W4295476639A5028860077 @default.
• W4295476639 hasAuthorship W4295476639A5036332505 @default.
• W4295476639 hasConcept C147483822 @default.
• W4295476639 hasConcept C185592680 @default.
• W4295476639 hasConcept C19317047 @default.
• W4295476639 hasConcept C195616568 @default.
• W4295476639 hasConcept C203014093 @default.
• W4295476639 hasConcept C207936829 @default.
• W4295476639 hasConcept C2776090121 @default.
• W4295476639 hasConcept C2777119779 @default.
• W4295476639 hasConcept C2779281246 @default.
• W4295476639 hasConcept C51323132 @default.
• W4295476639 hasConcept C553184892 @default.
• W4295476639 hasConcept C55493867 @default.
• W4295476639 hasConcept C60644358 @default.
• W4295476639 hasConcept C70721500 @default.
• W4295476639 hasConcept C86803240 @default.
• W4295476639 hasConcept C8891405 @default.
• W4295476639 hasConceptScore W4295476639C147483822 @default.
• W4295476639 hasConceptScore W4295476639C185592680 @default.
• W4295476639 hasConceptScore W4295476639C19317047 @default.
• W4295476639 hasConceptScore W4295476639C195616568 @default.
• W4295476639 hasConceptScore W4295476639C203014093 @default.
• W4295476639 hasConceptScore W4295476639C207936829 @default.
• W4295476639 hasConceptScore W4295476639C2776090121 @default.
• W4295476639 hasConceptScore W4295476639C2777119779 @default.
• W4295476639 hasConceptScore W4295476639C2779281246 @default.
• W4295476639 hasConceptScore W4295476639C51323132 @default.
• W4295476639 hasConceptScore W4295476639C553184892 @default.
• W4295476639 hasConceptScore W4295476639C55493867 @default.
• W4295476639 hasConceptScore W4295476639C60644358 @default.
• W4295476639 hasConceptScore W4295476639C70721500 @default.
• W4295476639 hasConceptScore W4295476639C86803240 @default.
• W4295476639 hasConceptScore W4295476639C8891405 @default.
• W4295476639 hasLocation W42954766391 @default.
• W4295476639 hasLocation W42954766392 @default.
• W4295476639 hasOpenAccess W4295476639 @default.
• W4295476639 hasPrimaryLocation W42954766391 @default.
• W4295476639 hasRelatedWork W1609618324 @default.
• W4295476639 hasRelatedWork W2098228613 @default.
• W4295476639 hasRelatedWork W2799935936 @default.
• W4295476639 hasRelatedWork W2924619580 @default.
• W4295476639 hasRelatedWork W2938592129 @default.

• next