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- W4295560326 endingPage "1436" @default.
- W4295560326 startingPage "1436" @default.
- W4295560326 abstract "Ischemic stroke is a detrimental neurological disease characterized by an irreversible infarct core surrounded by an ischemic penumbra, a salvageable region of brain tissue. Unique roles of distinct brain cell subpopulations within the neurovascular unit and peripheral immune cells during ischemic stroke remain elusive due to the heterogeneity of cells in the brain. Single-cell RNA sequencing (scRNA-seq) allows for an unbiased determination of cellular heterogeneity at high-resolution and identification of cell markers, thereby unveiling the principal brain clusters within the cell-type-specific gene expression patterns as well as cell-specific subclusters and their functions in different pathways underlying ischemic stroke. In this review, we have summarized the changes in differentiation trajectories of distinct cell types and highlighted the specific pathways and genes in brain cells that are impacted by stroke. This review is expected to inspire new research and provide directions for investigating the potential pathological mechanisms and novel treatment strategies for ischemic stroke at the level of a single cell." @default.
- W4295560326 created "2022-09-14" @default.
- W4295560326 creator A5011874331 @default.
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- W4295560326 date "2022-01-01" @default.
- W4295560326 modified "2023-10-14" @default.
- W4295560326 title "Cell Heterogeneity Uncovered by Single-Cell RNA Sequencing Offers Potential Therapeutic Targets for Ischemic Stroke" @default.
- W4295560326 cites W1434389346 @default.
- W4295560326 cites W1537642251 @default.
- W4295560326 cites W1546478791 @default.
- W4295560326 cites W1576809668 @default.
- W4295560326 cites W1666901150 @default.
- W4295560326 cites W1768846296 @default.
- W4295560326 cites W1964730250 @default.
- W4295560326 cites W1965180960 @default.
- W4295560326 cites W1968057097 @default.
- W4295560326 cites W1970215478 @default.
- W4295560326 cites W1985402737 @default.
- W4295560326 cites W1988215889 @default.
- W4295560326 cites W1994387916 @default.
- W4295560326 cites W1998907224 @default.
- W4295560326 cites W1999235115 @default.
- W4295560326 cites W2001023212 @default.
- W4295560326 cites W2005130936 @default.
- W4295560326 cites W2010922413 @default.
- W4295560326 cites W2016772236 @default.
- W4295560326 cites W2023749167 @default.
- W4295560326 cites W2025477103 @default.
- W4295560326 cites W2030566077 @default.
- W4295560326 cites W2032348735 @default.
- W4295560326 cites W2050597784 @default.
- W4295560326 cites W2051780876 @default.
- W4295560326 cites W2054624000 @default.
- W4295560326 cites W2055596465 @default.
- W4295560326 cites W2057422278 @default.
- W4295560326 cites W2069893872 @default.
- W4295560326 cites W2071252381 @default.
- W4295560326 cites W2074405990 @default.
- W4295560326 cites W2077720998 @default.
- W4295560326 cites W2083348332 @default.
- W4295560326 cites W2085293124 @default.
- W4295560326 cites W2089725161 @default.
- W4295560326 cites W2095214727 @default.
- W4295560326 cites W2098038342 @default.
- W4295560326 cites W2101363175 @default.
- W4295560326 cites W2103105379 @default.
- W4295560326 cites W2112094579 @default.
- W4295560326 cites W2115620368 @default.
- W4295560326 cites W2118200665 @default.
- W4295560326 cites W2125236750 @default.
- W4295560326 cites W2125411036 @default.
- W4295560326 cites W2126722631 @default.
- W4295560326 cites W2129262403 @default.
- W4295560326 cites W2133428572 @default.
- W4295560326 cites W2141036004 @default.
- W4295560326 cites W2143062996 @default.
- W4295560326 cites W2147372806 @default.
- W4295560326 cites W2151262021 @default.
- W4295560326 cites W2155344647 @default.
- W4295560326 cites W2160935383 @default.
- W4295560326 cites W2166219187 @default.
- W4295560326 cites W2180744905 @default.
- W4295560326 cites W2209349785 @default.
- W4295560326 cites W2262503792 @default.
- W4295560326 cites W2280881439 @default.
- W4295560326 cites W2328326888 @default.
- W4295560326 cites W2336440223 @default.
- W4295560326 cites W2336534940 @default.
- W4295560326 cites W2340240237 @default.
- W4295560326 cites W2397416734 @default.
- W4295560326 cites W2399776559 @default.
- W4295560326 cites W2409091607 @default.
- W4295560326 cites W2409354988 @default.
- W4295560326 cites W2431079001 @default.
- W4295560326 cites W2473785740 @default.
- W4295560326 cites W2503832164 @default.
- W4295560326 cites W2517534055 @default.
- W4295560326 cites W2527645962 @default.
- W4295560326 cites W2529479402 @default.
- W4295560326 cites W2551329787 @default.
- W4295560326 cites W2561508962 @default.
- W4295560326 cites W2572173857 @default.
- W4295560326 cites W2581069257 @default.
- W4295560326 cites W2584646669 @default.
- W4295560326 cites W2597009931 @default.
- W4295560326 cites W2612194812 @default.
- W4295560326 cites W2616922646 @default.
- W4295560326 cites W2626078173 @default.
- W4295560326 cites W2700330585 @default.
- W4295560326 cites W2736038609 @default.
- W4295560326 cites W2751637000 @default.