Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295560930> ?p ?o ?g. }
- W4295560930 endingPage "4394" @default.
- W4295560930 startingPage "4394" @default.
- W4295560930 abstract "The therapeutic approaches to cancer remain a considerable target for all scientists around the world. Although new cancer treatments are an everyday phenomenon, cancer still remains one of the leading mortality causes. Colorectal cancer (CRC) remains in this category, although patients with CRC may have better survival compared with other malignancies. Not only the tumor but also its environment, what we call the tumor microenvironment (TME), seem to contribute to cancer progression and resistance to therapy. TME consists of different molecules and cells. Cancer-associated fibroblasts are a major component. They arise from normal fibroblasts and other normal cells through various pathways. Their role seems to contribute to cancer promotion, participating in tumorigenesis, proliferation, growth, invasion, metastasis and resistance to treatment. Different markers, such as a-SMA, FAP, PDGFR-β, periostin, have been used for the detection of cancer-associated fibroblasts (CAFs). Their detection is important for two main reasons; research has shown that their existence is correlated with prognosis, and they are already under evaluation as a possible target for treatment. However, extensive research is warranted." @default.
- W4295560930 created "2022-09-14" @default.
- W4295560930 creator A5002261243 @default.
- W4295560930 creator A5020517807 @default.
- W4295560930 creator A5035160587 @default.
- W4295560930 creator A5036536314 @default.
- W4295560930 creator A5067611572 @default.
- W4295560930 creator A5078192662 @default.
- W4295560930 creator A5081984487 @default.
- W4295560930 date "2022-09-09" @default.
- W4295560930 modified "2023-09-30" @default.
- W4295560930 title "Cancer-Associated Fibroblasts: The Origin, Biological Characteristics and Role in Cancer—A Glance on Colorectal Cancer" @default.
- W4295560930 cites W115384338 @default.
- W4295560930 cites W1572890328 @default.
- W4295560930 cites W1579383624 @default.
- W4295560930 cites W1585754595 @default.
- W4295560930 cites W1757299625 @default.
- W4295560930 cites W1833466701 @default.
- W4295560930 cites W1867576261 @default.
- W4295560930 cites W1877248121 @default.
- W4295560930 cites W1907149477 @default.
- W4295560930 cites W1914096163 @default.
- W4295560930 cites W1934094702 @default.
- W4295560930 cites W1938802559 @default.
- W4295560930 cites W1952391983 @default.
- W4295560930 cites W1959606306 @default.
- W4295560930 cites W1964244253 @default.
- W4295560930 cites W1965498876 @default.
- W4295560930 cites W1965588383 @default.
- W4295560930 cites W1966551238 @default.
- W4295560930 cites W1972196680 @default.
- W4295560930 cites W1974734114 @default.
- W4295560930 cites W1977381126 @default.
- W4295560930 cites W1986066912 @default.
- W4295560930 cites W1986612792 @default.
- W4295560930 cites W1987313116 @default.
- W4295560930 cites W1987628377 @default.
- W4295560930 cites W1991225025 @default.
- W4295560930 cites W1996213381 @default.
- W4295560930 cites W1996879480 @default.
- W4295560930 cites W1998717940 @default.
- W4295560930 cites W2006252261 @default.
- W4295560930 cites W2006540291 @default.
- W4295560930 cites W2006628284 @default.
- W4295560930 cites W2007040134 @default.
- W4295560930 cites W2008189345 @default.
- W4295560930 cites W2008650765 @default.
- W4295560930 cites W2011975049 @default.
- W4295560930 cites W2019922483 @default.
- W4295560930 cites W2020087937 @default.
- W4295560930 cites W2023026872 @default.
- W4295560930 cites W2023805473 @default.
- W4295560930 cites W2026727204 @default.
- W4295560930 cites W2030739171 @default.
- W4295560930 cites W2030797581 @default.
- W4295560930 cites W2033973727 @default.
- W4295560930 cites W2034732819 @default.
- W4295560930 cites W2038569449 @default.
- W4295560930 cites W2039775205 @default.
- W4295560930 cites W2041532660 @default.
- W4295560930 cites W2041838266 @default.
- W4295560930 cites W2042082129 @default.
- W4295560930 cites W2049258429 @default.
- W4295560930 cites W2049317749 @default.
- W4295560930 cites W2051696368 @default.
- W4295560930 cites W2054282870 @default.
- W4295560930 cites W2054526193 @default.
- W4295560930 cites W2055463899 @default.
- W4295560930 cites W2056574134 @default.
- W4295560930 cites W2059403516 @default.
- W4295560930 cites W2060672294 @default.
- W4295560930 cites W2061581062 @default.
- W4295560930 cites W2062004524 @default.
- W4295560930 cites W2062265555 @default.
- W4295560930 cites W2062461507 @default.
- W4295560930 cites W2062809449 @default.
- W4295560930 cites W2064297038 @default.
- W4295560930 cites W2067311124 @default.
- W4295560930 cites W2072194461 @default.
- W4295560930 cites W2072703892 @default.
- W4295560930 cites W2075077128 @default.
- W4295560930 cites W2075261412 @default.
- W4295560930 cites W2075465677 @default.
- W4295560930 cites W2078323166 @default.
- W4295560930 cites W2080860848 @default.
- W4295560930 cites W2082046119 @default.
- W4295560930 cites W2085963386 @default.
- W4295560930 cites W2086834665 @default.
- W4295560930 cites W2088172066 @default.
- W4295560930 cites W2089251684 @default.
- W4295560930 cites W2089704546 @default.
- W4295560930 cites W2089706191 @default.
- W4295560930 cites W2093463613 @default.
- W4295560930 cites W2097862336 @default.
- W4295560930 cites W2101037339 @default.
- W4295560930 cites W2102322990 @default.
- W4295560930 cites W2102944868 @default.
- W4295560930 cites W2103328690 @default.