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- W4295771633 abstract "Albutrepenonacog-alfa (Idelvion®, CSL Behring) is a recombinant fusion protein in which the recombinant FIX (rFIX) links a recombinant human albumin, extending the half-life of rFIX even beyond 100 hours. In 2016, this drug was approved worldwide for the treatment of pediatric and adult persons with hemophilia B (PWH-B). Its efficacy and safety were described in the PROLONG-9FP program and subsequently confirmed in the real-world practice, even if to date there are not many manuscripts that extensively and completely deal with the use of albutrepenonacog-alfa in daily practice, also evaluating its impact on the quality of life of patients treated with this drug; this review therefore aims to analyze all the publications currently available regarding the real-world use of this extended half-life concentrate, also noting which topics need further study and research." @default.
- W4295771633 created "2022-09-15" @default.
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- W4295771633 date "2022-09-01" @default.
- W4295771633 modified "2023-10-14" @default.
- W4295771633 title "Albumin-Fusion Recombinant FIX in the Management of People with Hemophilia B: An Evidence-Based Review" @default.
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- W4295771633 doi "https://doi.org/10.2147/dddt.s236788" @default.
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