FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295777920> ?p ?o ?g. }

• W4295777920 endingPage "103842" @default.
• W4295777920 startingPage "103842" @default.
• W4295777920 abstract "Diapause is one of the most important traits that have sustained insects to thrive. To survive harsh seasons, most insects can arrest their development and enter diapause. The photoperiod is the signal that indicates insects the proper timing to enter diapause. Circadian clock genes are shown to be involved in photoperiodic diapause induction in various insect species. The silkworm, Bombyx mori, enters diapause at the embryonic stage. In bivoltine strains, diapause determination is under maternal control and affected by temperature and photoperiodic conditions that mothers experienced during embryonic and larval stages. Two independent studies showed that knocking out the core clock gene, period, perturb photoperiodic diapause induction in B. mori. However, whether the circadian clock as whole or individual clock genes are responsible for the photoperiodic diapause induction remains unknown. In this study, using CRISPR/Cas9 we knocked out negative (period and timeless) and positive elements (Clock and cycle) in p50T, a bivoltine strain which exhibits photoperiodic diapause induction during both embryonic and larval stages. The temporal expression patterns of clock genes changed in each core clock gene knockout strain, suggesting disruption of normal feedback loops produced by circadian clock genes. Furthermore, the ability of female moths to appropriately produce diapause or non-diapause eggs in response to photoperiod in both embryonic and larval stages was lost in all knockout strains. Our results indicate the involvement of circadian clock in photoperiodic diapause induction in B. mori." @default.
• W4295777920 created "2022-09-15" @default.
• W4295777920 creator A5007789584 @default.
• W4295777920 creator A5062020149 @default.
• W4295777920 date "2022-10-01" @default.
• W4295777920 modified "2023-10-03" @default.
• W4295777920 title "Knockouts of positive and negative elements of the circadian clock disrupt photoperiodic diapause induction in the silkworm, Bombyx mori" @default.
• W4295777920 cites W1481999684 @default.
• W4295777920 cites W1504564486 @default.
• W4295777920 cites W1825981987 @default.
• W4295777920 cites W1892228382 @default.
• W4295777920 cites W1968755313 @default.
• W4295777920 cites W1970549334 @default.
• W4295777920 cites W1978811776 @default.
• W4295777920 cites W1985265839 @default.
• W4295777920 cites W1990354445 @default.
• W4295777920 cites W1995023912 @default.
• W4295777920 cites W1997070203 @default.
• W4295777920 cites W1997213971 @default.
• W4295777920 cites W2007743240 @default.
• W4295777920 cites W2009815448 @default.
• W4295777920 cites W2022987439 @default.
• W4295777920 cites W2025885587 @default.
• W4295777920 cites W2037118780 @default.
• W4295777920 cites W2054351595 @default.
• W4295777920 cites W2059186228 @default.
• W4295777920 cites W2063825124 @default.
• W4295777920 cites W2065793682 @default.
• W4295777920 cites W2068349936 @default.
• W4295777920 cites W2071738414 @default.
• W4295777920 cites W2079857188 @default.
• W4295777920 cites W2081266461 @default.
• W4295777920 cites W2092882299 @default.
• W4295777920 cites W2092934538 @default.
• W4295777920 cites W2095514153 @default.
• W4295777920 cites W2096155731 @default.
• W4295777920 cites W2107320846 @default.
• W4295777920 cites W2114427883 @default.
• W4295777920 cites W2115839035 @default.
• W4295777920 cites W2122109272 @default.
• W4295777920 cites W2123634741 @default.
• W4295777920 cites W2136127196 @default.
• W4295777920 cites W2138665253 @default.
• W4295777920 cites W2145517507 @default.
• W4295777920 cites W2145782793 @default.
• W4295777920 cites W2146656260 @default.
• W4295777920 cites W2146991617 @default.
• W4295777920 cites W2147739177 @default.
• W4295777920 cites W2151305846 @default.
• W4295777920 cites W2154076545 @default.
• W4295777920 cites W2157490739 @default.
• W4295777920 cites W2158235544 @default.
• W4295777920 cites W2161858704 @default.
• W4295777920 cites W2163630217 @default.
• W4295777920 cites W2168288068 @default.
• W4295777920 cites W2243540852 @default.
• W4295777920 cites W2305214094 @default.
• W4295777920 cites W2516006289 @default.
• W4295777920 cites W2594593037 @default.
• W4295777920 cites W2618656749 @default.
• W4295777920 cites W2737294952 @default.
• W4295777920 cites W2753287959 @default.
• W4295777920 cites W2886401172 @default.
• W4295777920 cites W2916114485 @default.
• W4295777920 cites W2926099279 @default.
• W4295777920 cites W2991515832 @default.
• W4295777920 cites W3080500186 @default.
• W4295777920 cites W3108429045 @default.
• W4295777920 cites W3180314031 @default.
• W4295777920 cites W3198449435 @default.
• W4295777920 cites W3202415367 @default.
• W4295777920 cites W4200027960 @default.
• W4295777920 cites W4206759545 @default.
• W4295777920 cites W4224929316 @default.
• W4295777920 cites W4225131176 @default.
• W4295777920 cites W4235561975 @default.
• W4295777920 cites W4235754367 @default.
• W4295777920 doi "https://doi.org/10.1016/j.ibmb.2022.103842" @default.
• W4295777920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36115518" @default.
• W4295777920 hasPublicationYear "2022" @default.
• W4295777920 type Work @default.
• W4295777920 citedByCount "6" @default.
• W4295777920 countsByYear W42957779202023 @default.
• W4295777920 crossrefType "journal-article" @default.
• W4295777920 hasAuthorship W4295777920A5007789584 @default.
• W4295777920 hasAuthorship W4295777920A5062020149 @default.
• W4295777920 hasBestOaLocation W42957779202 @default.
• W4295777920 hasConcept C104317684 @default.
• W4295777920 hasConcept C121332964 @default.
• W4295777920 hasConcept C121446783 @default.
• W4295777920 hasConcept C133805834 @default.
• W4295777920 hasConcept C134018914 @default.
• W4295777920 hasConcept C173758957 @default.
• W4295777920 hasConcept C184738001 @default.
• W4295777920 hasConcept C24890656 @default.
• W4295777920 hasConcept C2778332815 @default.
• W4295777920 hasConcept C2778487026 @default.
• W4295777920 hasConcept C2781291010 @default.

• next