Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295847129> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4295847129 endingPage "5434" @default.
- W4295847129 startingPage "5425" @default.
- W4295847129 abstract "To analyze the contribution of metagenomic next-generation sequencing (mNGS) in the guidance of clinical treatment and outcomes of infection during myelosuppression among children with hematological and neoplastic diseases.The clinical data and results of mNGS assay of febrile patients suspected of infection were retrospectively collected. The characteristics of pathogenic microorganisms and clinical course of myelosuppressed children with hematological diseases were summarized.Our study included 70 patients (45 males) with a median age of 5 years (range: 0.5 to 13 y). During the study period, there were 96 events of suspected infection. According to comprehensive clinical diagnosis, 73 blood infections, 43 pneumonia and 2 urinary tract infections occurred. The positive rate of mNGS was significantly higher than that of traditional microbial detection (83.3% vs 17.7%). The main pathogens detected by mNGS were Pseudomonas aeruginosa, Acinetobacter, human herpesvirus, Candida and Aspergillus. The average duration of fever was 4.9 days and 11.6 days (P < 0.05), and the average cost of anti-infection treatment was RMB ¥28,077 and 39,898 (P < 0.05) among children received mNGS within 48 hours and more than 48 hours after the onset of infection symptoms.mNGS contributes to clinical management of children with infection during myelosuppression, especially among patients with negative traditional microbial detection. Early implementation of mNGS in children with symptoms has a tendency to reduce the time of infection, fever and the cost of treatment." @default.
- W4295847129 created "2022-09-15" @default.
- W4295847129 creator A5006898135 @default.
- W4295847129 creator A5007510504 @default.
- W4295847129 creator A5009880860 @default.
- W4295847129 creator A5019240275 @default.
- W4295847129 creator A5020425902 @default.
- W4295847129 creator A5020730562 @default.
- W4295847129 creator A5020929077 @default.
- W4295847129 creator A5036392227 @default.
- W4295847129 creator A5067043064 @default.
- W4295847129 date "2022-09-01" @default.
- W4295847129 modified "2023-10-18" @default.
- W4295847129 title "Metagenomic Next-Generation Sequencing in the Diagnosis of Infectious Fever During Myelosuppression Among Pediatric Patients with Hematological and Neoplastic Diseases" @default.
- W4295847129 cites W1969040342 @default.
- W4295847129 cites W2055043387 @default.
- W4295847129 cites W2083336892 @default.
- W4295847129 cites W2091900888 @default.
- W4295847129 cites W2123859227 @default.
- W4295847129 cites W2127344129 @default.
- W4295847129 cites W2133979383 @default.
- W4295847129 cites W2138096026 @default.
- W4295847129 cites W2215646221 @default.
- W4295847129 cites W2463042271 @default.
- W4295847129 cites W2510137764 @default.
- W4295847129 cites W2587565773 @default.
- W4295847129 cites W2594239319 @default.
- W4295847129 cites W2726960688 @default.
- W4295847129 cites W2898604559 @default.
- W4295847129 cites W2900288673 @default.
- W4295847129 cites W2903912375 @default.
- W4295847129 cites W2924005961 @default.
- W4295847129 cites W2948132003 @default.
- W4295847129 cites W2948863627 @default.
- W4295847129 cites W2970471457 @default.
- W4295847129 cites W3000477794 @default.
- W4295847129 cites W3006687689 @default.
- W4295847129 cites W3011028253 @default.
- W4295847129 cites W3041603820 @default.
- W4295847129 cites W3048660918 @default.
- W4295847129 doi "https://doi.org/10.2147/idr.s379582" @default.
- W4295847129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36124109" @default.
- W4295847129 hasPublicationYear "2022" @default.
- W4295847129 type Work @default.
- W4295847129 citedByCount "1" @default.
- W4295847129 countsByYear W42958471292023 @default.
- W4295847129 crossrefType "journal-article" @default.
- W4295847129 hasAuthorship W4295847129A5006898135 @default.
- W4295847129 hasAuthorship W4295847129A5007510504 @default.
- W4295847129 hasAuthorship W4295847129A5009880860 @default.
- W4295847129 hasAuthorship W4295847129A5019240275 @default.
- W4295847129 hasAuthorship W4295847129A5020425902 @default.
- W4295847129 hasAuthorship W4295847129A5020730562 @default.
- W4295847129 hasAuthorship W4295847129A5020929077 @default.
- W4295847129 hasAuthorship W4295847129A5036392227 @default.
- W4295847129 hasAuthorship W4295847129A5067043064 @default.
- W4295847129 hasBestOaLocation W42958471291 @default.
- W4295847129 hasConcept C126322002 @default.
- W4295847129 hasConcept C203014093 @default.
- W4295847129 hasConcept C2777914695 @default.
- W4295847129 hasConcept C501593827 @default.
- W4295847129 hasConcept C71924100 @default.
- W4295847129 hasConcept C86803240 @default.
- W4295847129 hasConcept C89423630 @default.
- W4295847129 hasConceptScore W4295847129C126322002 @default.
- W4295847129 hasConceptScore W4295847129C203014093 @default.
- W4295847129 hasConceptScore W4295847129C2777914695 @default.
- W4295847129 hasConceptScore W4295847129C501593827 @default.
- W4295847129 hasConceptScore W4295847129C71924100 @default.
- W4295847129 hasConceptScore W4295847129C86803240 @default.
- W4295847129 hasConceptScore W4295847129C89423630 @default.
- W4295847129 hasLocation W42958471291 @default.
- W4295847129 hasLocation W42958471292 @default.
- W4295847129 hasLocation W42958471293 @default.
- W4295847129 hasOpenAccess W4295847129 @default.
- W4295847129 hasPrimaryLocation W42958471291 @default.
- W4295847129 hasRelatedWork W1877883789 @default.
- W4295847129 hasRelatedWork W1978956552 @default.
- W4295847129 hasRelatedWork W2247376599 @default.
- W4295847129 hasRelatedWork W2316236384 @default.
- W4295847129 hasRelatedWork W2382293659 @default.
- W4295847129 hasRelatedWork W2416847589 @default.
- W4295847129 hasRelatedWork W2474749474 @default.
- W4295847129 hasRelatedWork W2944055074 @default.
- W4295847129 hasRelatedWork W4253808419 @default.
- W4295847129 hasRelatedWork W4383736115 @default.
- W4295847129 hasVolume "Volume 15" @default.
- W4295847129 isParatext "false" @default.
- W4295847129 isRetracted "false" @default.
- W4295847129 workType "article" @default.