Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295854201> ?p ?o ?g. }
- W4295854201 endingPage "117" @default.
- W4295854201 startingPage "105" @default.
- W4295854201 abstract "Basal cell carcinoma (BCC) is the most common form of skin cancer and responsible for most of the cancer related morbidities and pose a significant public health concern worldwide. Surgery treatment modality is able to clear the BCC, yet it mostly leads to scar formation. Plasmonic photothermal therapy (PPTT) which involves using gold nanostructures and near-infrared (NIR) light to kill the BCC cells by local heating is associated with excellent tissue preservation and healing without scarring. Parenteral administration of such gold nanostructures suffers from off-target delivery and side effects. Delivering such phototherapeutics directly to the BCC proved to be an attractive alternative route of administration yet encountered with penetration limitations due to the stratum corneum (SC) fierce barrier. In the current study, we developed and optimised a novel NIR light-responsive hydrogel-forming long needle (HFLN) loaded with Gold nanorods (GNRs) as a potential plasmonic photothermal device for localised treatment of nodular BCC. The HFLN was prepared from Gantrez® S-97 and poly(ethylene glycol) (PEG) 200 Da and characterized in terms of swelling, insertion and mechanical properties. GNRs were synthesised and tunned using seed-mediated growth method. The integrated devices developed could revolutionise BCC treatment benefiting both patients and healthcare providers." @default.
- W4295854201 created "2022-09-15" @default.
- W4295854201 creator A5047247818 @default.
- W4295854201 creator A5059207450 @default.
- W4295854201 creator A5087077311 @default.
- W4295854201 date "2022-10-01" @default.
- W4295854201 modified "2023-10-10" @default.
- W4295854201 title "Gold nanorods-loaded hydrogel-forming needles for local hyperthermia applications: Proof of concept" @default.
- W4295854201 cites W1529230314 @default.
- W4295854201 cites W1540044642 @default.
- W4295854201 cites W1964250581 @default.
- W4295854201 cites W1969451341 @default.
- W4295854201 cites W1969583366 @default.
- W4295854201 cites W1970911113 @default.
- W4295854201 cites W1971941564 @default.
- W4295854201 cites W1974623959 @default.
- W4295854201 cites W1981512405 @default.
- W4295854201 cites W1988755267 @default.
- W4295854201 cites W1992843088 @default.
- W4295854201 cites W1997479687 @default.
- W4295854201 cites W1998263769 @default.
- W4295854201 cites W2002060850 @default.
- W4295854201 cites W2009747367 @default.
- W4295854201 cites W2011363406 @default.
- W4295854201 cites W2016962388 @default.
- W4295854201 cites W2037048276 @default.
- W4295854201 cites W2040332674 @default.
- W4295854201 cites W2043009832 @default.
- W4295854201 cites W2048050518 @default.
- W4295854201 cites W2049037588 @default.
- W4295854201 cites W2050321155 @default.
- W4295854201 cites W2050555966 @default.
- W4295854201 cites W2052589039 @default.
- W4295854201 cites W2054294261 @default.
- W4295854201 cites W2055721190 @default.
- W4295854201 cites W2065845122 @default.
- W4295854201 cites W2070819648 @default.
- W4295854201 cites W2075001207 @default.
- W4295854201 cites W2077086790 @default.
- W4295854201 cites W2077228161 @default.
- W4295854201 cites W2077863403 @default.
- W4295854201 cites W2087812848 @default.
- W4295854201 cites W2091257316 @default.
- W4295854201 cites W2093887316 @default.
- W4295854201 cites W2093897877 @default.
- W4295854201 cites W2096207257 @default.
- W4295854201 cites W2107298907 @default.
- W4295854201 cites W2117326659 @default.
- W4295854201 cites W2133485231 @default.
- W4295854201 cites W2134304198 @default.
- W4295854201 cites W2135746650 @default.
- W4295854201 cites W2138037987 @default.
- W4295854201 cites W2145342077 @default.
- W4295854201 cites W2156124327 @default.
- W4295854201 cites W2162034088 @default.
- W4295854201 cites W2168309066 @default.
- W4295854201 cites W2170875212 @default.
- W4295854201 cites W2269455206 @default.
- W4295854201 cites W2312941501 @default.
- W4295854201 cites W2322194440 @default.
- W4295854201 cites W2327352318 @default.
- W4295854201 cites W2409984077 @default.
- W4295854201 cites W2410691776 @default.
- W4295854201 cites W2606605131 @default.
- W4295854201 cites W2914685428 @default.
- W4295854201 cites W3019655035 @default.
- W4295854201 cites W3037569530 @default.
- W4295854201 cites W3125417938 @default.
- W4295854201 cites W3126762084 @default.
- W4295854201 cites W3165072679 @default.
- W4295854201 cites W4243789790 @default.
- W4295854201 cites W4246958924 @default.
- W4295854201 cites W4252865728 @default.
- W4295854201 cites W4283390106 @default.
- W4295854201 doi "https://doi.org/10.1016/j.ejpb.2022.08.022" @default.
- W4295854201 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36067956" @default.
- W4295854201 hasPublicationYear "2022" @default.
- W4295854201 type Work @default.
- W4295854201 citedByCount "1" @default.
- W4295854201 countsByYear W42958542012023 @default.
- W4295854201 crossrefType "journal-article" @default.
- W4295854201 hasAuthorship W4295854201A5047247818 @default.
- W4295854201 hasAuthorship W4295854201A5059207450 @default.
- W4295854201 hasAuthorship W4295854201A5087077311 @default.
- W4295854201 hasConcept C104819515 @default.
- W4295854201 hasConcept C121608353 @default.
- W4295854201 hasConcept C126201875 @default.
- W4295854201 hasConcept C126322002 @default.
- W4295854201 hasConcept C127413603 @default.
- W4295854201 hasConcept C136229726 @default.
- W4295854201 hasConcept C142724271 @default.
- W4295854201 hasConcept C155672457 @default.
- W4295854201 hasConcept C171250308 @default.
- W4295854201 hasConcept C178790620 @default.
- W4295854201 hasConcept C182606246 @default.
- W4295854201 hasConcept C185592680 @default.
- W4295854201 hasConcept C192562407 @default.
- W4295854201 hasConcept C2777516009 @default.