Matches in SemOpenAlex for { <https://semopenalex.org/work/W4295900529> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4295900529 abstract "Allogenic blood product usage is associated with worse outcomes in open repair of descending and thoracoabdominal aortic aneurysms. This pilot study evaluated the safety and efficacy of a novel modification of the left heart bypass (LHB) circuit to reduce intraoperative blood transfusions.In modified LHB, pump suckers collected shed blood that was directly retransfused through a femoral vein cannula. In standard LHB, cellsavers were used to collect, wash, and retransfuse shed blood. Consecutive patients undergoing elective surgical descending or thoracoabdominal aneurysm repair using modified (N.=12) or standard (N.=21) LHB were compared. Intraoperative blood product use was the primary outcome. Hypotensive episodes, lactate levels, and adverse events (early mortality, spinal cord injury, renal and respiratory insufficiency) were secondary outcomes.Groups were comparable regarding pre- and intraoperative variables. No perfusion-related adverse events occurred. With modified LHB, intraoperative blood product use was significantly reduced: packed red blood cells by 60% from 10 to 4 units (P=0.002), fresh frozen plasma by 70% from 17 to 5 units (P<0.001) as well as retransfused cellsaver volume by 75%, from 4500 mL to 1110 mL (P<0.001). Hemodynamic instability occurred in 1 (8.3%) vs. 6 (29%), P=0.22 and overall lactate levels were significantly reduced (P=0.045) with modified LHB. Adverse events combined occurred in 1/12 vs. (P=0.022).The novel modified LHB with direct retransfusion was safe and associated with significantly reduced intraoperative blood product use, reduced lactate production and improved clinical outcomes as compared to standard LHB and could represent an important clinical improvement." @default.
- W4295900529 created "2022-09-16" @default.
- W4295900529 creator A5024179266 @default.
- W4295900529 creator A5028130743 @default.
- W4295900529 creator A5045177805 @default.
- W4295900529 creator A5049865773 @default.
- W4295900529 creator A5051271906 @default.
- W4295900529 creator A5052067701 @default.
- W4295900529 creator A5054289298 @default.
- W4295900529 creator A5079061082 @default.
- W4295900529 creator A5087911645 @default.
- W4295900529 date "2022-12-01" @default.
- W4295900529 modified "2023-10-14" @default.
- W4295900529 title "Novel method for direct retransfusion reduces blood transfusions in descending and thoracoabdominal aneurysm repair" @default.
- W4295900529 cites W1971748281 @default.
- W4295900529 cites W2031976208 @default.
- W4295900529 cites W2067481362 @default.
- W4295900529 cites W2068793436 @default.
- W4295900529 cites W2148135744 @default.
- W4295900529 cites W2331403647 @default.
- W4295900529 cites W2570738377 @default.
- W4295900529 cites W2602871803 @default.
- W4295900529 cites W2795647259 @default.
- W4295900529 cites W2802822333 @default.
- W4295900529 cites W2914209347 @default.
- W4295900529 cites W3036695436 @default.
- W4295900529 cites W3081714701 @default.
- W4295900529 cites W3175380572 @default.
- W4295900529 cites W3186034571 @default.
- W4295900529 doi "https://doi.org/10.23736/s0021-9509.22.12415-8" @default.
- W4295900529 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36106399" @default.
- W4295900529 hasPublicationYear "2022" @default.
- W4295900529 type Work @default.
- W4295900529 citedByCount "0" @default.
- W4295900529 crossrefType "journal-article" @default.
- W4295900529 hasAuthorship W4295900529A5024179266 @default.
- W4295900529 hasAuthorship W4295900529A5028130743 @default.
- W4295900529 hasAuthorship W4295900529A5045177805 @default.
- W4295900529 hasAuthorship W4295900529A5049865773 @default.
- W4295900529 hasAuthorship W4295900529A5051271906 @default.
- W4295900529 hasAuthorship W4295900529A5052067701 @default.
- W4295900529 hasAuthorship W4295900529A5054289298 @default.
- W4295900529 hasAuthorship W4295900529A5079061082 @default.
- W4295900529 hasAuthorship W4295900529A5087911645 @default.
- W4295900529 hasBestOaLocation W42959005291 @default.
- W4295900529 hasConcept C126322002 @default.
- W4295900529 hasConcept C141071460 @default.
- W4295900529 hasConcept C178853913 @default.
- W4295900529 hasConcept C197934379 @default.
- W4295900529 hasConcept C2777396833 @default.
- W4295900529 hasConcept C2778074680 @default.
- W4295900529 hasConcept C2778881276 @default.
- W4295900529 hasConcept C2780014101 @default.
- W4295900529 hasConcept C2780920261 @default.
- W4295900529 hasConcept C37557685 @default.
- W4295900529 hasConcept C42219234 @default.
- W4295900529 hasConcept C71924100 @default.
- W4295900529 hasConceptScore W4295900529C126322002 @default.
- W4295900529 hasConceptScore W4295900529C141071460 @default.
- W4295900529 hasConceptScore W4295900529C178853913 @default.
- W4295900529 hasConceptScore W4295900529C197934379 @default.
- W4295900529 hasConceptScore W4295900529C2777396833 @default.
- W4295900529 hasConceptScore W4295900529C2778074680 @default.
- W4295900529 hasConceptScore W4295900529C2778881276 @default.
- W4295900529 hasConceptScore W4295900529C2780014101 @default.
- W4295900529 hasConceptScore W4295900529C2780920261 @default.
- W4295900529 hasConceptScore W4295900529C37557685 @default.
- W4295900529 hasConceptScore W4295900529C42219234 @default.
- W4295900529 hasConceptScore W4295900529C71924100 @default.
- W4295900529 hasIssue "6" @default.
- W4295900529 hasLocation W42959005291 @default.
- W4295900529 hasLocation W42959005292 @default.
- W4295900529 hasOpenAccess W4295900529 @default.
- W4295900529 hasPrimaryLocation W42959005291 @default.
- W4295900529 hasRelatedWork W1607676551 @default.
- W4295900529 hasRelatedWork W2024648284 @default.
- W4295900529 hasRelatedWork W2105488322 @default.
- W4295900529 hasRelatedWork W2414408246 @default.
- W4295900529 hasRelatedWork W2504848554 @default.
- W4295900529 hasRelatedWork W3004752542 @default.
- W4295900529 hasRelatedWork W3009082176 @default.
- W4295900529 hasRelatedWork W4283465941 @default.
- W4295900529 hasRelatedWork W4382181682 @default.
- W4295900529 hasRelatedWork W4386260930 @default.
- W4295900529 hasVolume "63" @default.
- W4295900529 isParatext "false" @default.
- W4295900529 isRetracted "false" @default.
- W4295900529 workType "article" @default.