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- W4295978477 abstract "Predicting survival time for patients with spinal metastases is important in treatment choice. Generally speaking, six months is a landmark cutoff point. Revised Tokuhashi score (RTS), the most widely used scoring system, lost its accuracy in predicting 6-month survival, gradually. Therefore, a more precise scoring system is urgently needed.The aim of this study is to create a new scoring system with a higher accuracy in predicting 6-month survival based on the previously used RTS.Data of 171 patients were examined to determine factors that affect prognosis (reference group), and the remaining (validation group) were examined to validate the reliability of a new score, adjusted Tokuhashi score (ATS). We compared their discriminatory abilities of the prediction models using area under receiver operating characteristic curve (AUC).Target therapy and the Z score of BMI (Z-BMI), which adjusted to the patients' sex and age, were additional independent prognostic factors. Patients with target therapy use are awarded 4 points. The Z score of BMI could be added directly to yield ATS. The AUCs were 0.760 for ATS and 0.636 for RTS in the validation group.Appropriate target therapy use can prolong patients' survival. Z-BMI which might reflect nutritional status is another important influencing factor. With the optimization, surgeons could choose a more individualized treatment for patients." @default.
- W4295978477 created "2022-09-16" @default.
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- W4295978477 date "2022-09-14" @default.
- W4295978477 modified "2023-10-18" @default.
- W4295978477 title "Optimization of Tokuhashi Scoring System to Improve Survival Prediction in Patients with Spinal Metastases" @default.
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- W4295978477 doi "https://doi.org/10.3390/jcm11185391" @default.
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