FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296142904> ?p ?o ?g. }

• W4296142904 endingPage "111949" @default.
• W4296142904 startingPage "111949" @default.
• W4296142904 abstract "Golden berry (Physalis peruviana) is a tropical fruit rich in antioxidants that has been proposed to be able to control the lipid profile in hypercholesterolemic patients. Dyslipidemia is an independent risk factor for cardiometabolic diseases. The gut microbiota is strongly associated with cardiometabolic risk and is involved in redox balance, intestinal permeability, and inflammation. However, the impacts of golden berry on some of these factors, including the human gut microbiota, have never been tested, and there are no tools for compliance monitoring or dietary intake assessment regarding nutritional interventions with this fruit. In the pre-post quasi-experimental nutritional intervention presented here, 18 adult men (27-49 years old) consumed golden berries (Dorada variety) for three weeks. We evaluated putative biomarkers of exposure through an untargeted metabolomics approach (liquid chromatography-mass spectrometry LC-MS), quantified the biomarkers of oxidative stress, gut permeability, and inflammation in plasma, and assessed the effects of fruit intake on the gut microbiota through 16S rRNA gene sequencing of feces (Illumina MiSeq V2). First, syringic acid and kaempferol were identified as putative biomarkers of golden berry consumption. Intervention with this fruit promoted physiological changes in the participants after three weeks, reducing the level of the oxidative stress marker 8-isoprostane (-148 pg/ml; 36.1 %; p = 0.057) and slightly altering gut permeability by increasing the plasma levels of LBP (2.91 µg/ml; 54.6 %; p = 0.0005) and I-FABP (0.15, 14.7 %, p = 0.04) without inducing significant inflammation; i.e., the levels of IL-1β, TNF-α and IL-8 changed by 0.7 (2.0 %), -4.0 (-9.6 %) and -0.4 (-1.8 %) pg/ml, respectively. Notably, the consumption of golden berries did not affect the gut microbiota of the individuals consistently but instead shifted it in a personalized manner. The compositions of the gut microbiota of a given individual at the end of intervention and one month after the end of intervention were statistically more similar to their own baseline than to a corresponding sample from a different individual. This intervention identified putative biomarkers of golden berry intake along with potential benefits of its consumption relevant to cardiometabolic disease risk reduction. Golden berries are likely to positively modulate redox balance, although this effect must be proven in a future controlled clinical trial." @default.
• W4296142904 created "2022-09-17" @default.
• W4296142904 creator A5000875531 @default.
• W4296142904 creator A5001142608 @default.
• W4296142904 creator A5006069317 @default.
• W4296142904 creator A5055917432 @default.
• W4296142904 creator A5057031473 @default.
• W4296142904 creator A5059558683 @default.
• W4296142904 creator A5065261565 @default.
• W4296142904 creator A5091824285 @default.
• W4296142904 creator A5065710512 @default.
• W4296142904 date "2022-12-01" @default.
• W4296142904 modified "2023-10-16" @default.
• W4296142904 title "Consumption of golden berries (Physalis peruviana L.) might reduce biomarkers of oxidative stress and alter gut permeability in men without changing inflammation status or the gut microbiota" @default.
• W4296142904 cites W1959093477 @default.
• W4296142904 cites W1970548436 @default.
• W4296142904 cites W1990450412 @default.
• W4296142904 cites W1990590570 @default.
• W4296142904 cites W2009170813 @default.
• W4296142904 cites W2025873567 @default.
• W4296142904 cites W2045126465 @default.
• W4296142904 cites W2048213069 @default.
• W4296142904 cites W2050920580 @default.
• W4296142904 cites W2070391080 @default.
• W4296142904 cites W2077488126 @default.
• W4296142904 cites W2079183971 @default.
• W4296142904 cites W2088170171 @default.
• W4296142904 cites W2091802989 @default.
• W4296142904 cites W2100190412 @default.
• W4296142904 cites W2104183441 @default.
• W4296142904 cites W2109660771 @default.
• W4296142904 cites W2117457769 @default.
• W4296142904 cites W2119331100 @default.
• W4296142904 cites W2124034325 @default.
• W4296142904 cites W2128769815 @default.
• W4296142904 cites W2131308179 @default.
• W4296142904 cites W2131415145 @default.
• W4296142904 cites W2131536322 @default.
• W4296142904 cites W2147790901 @default.
• W4296142904 cites W2161749694 @default.
• W4296142904 cites W2166562121 @default.
• W4296142904 cites W2167062509 @default.
• W4296142904 cites W2169188936 @default.
• W4296142904 cites W2169908590 @default.
• W4296142904 cites W2174368446 @default.
• W4296142904 cites W2175465469 @default.
• W4296142904 cites W2388447520 @default.
• W4296142904 cites W2434635261 @default.
• W4296142904 cites W2464835332 @default.
• W4296142904 cites W2467200611 @default.
• W4296142904 cites W2522781403 @default.
• W4296142904 cites W2551972057 @default.
• W4296142904 cites W2553070638 @default.
• W4296142904 cites W2559267012 @default.
• W4296142904 cites W2595992107 @default.
• W4296142904 cites W2614616952 @default.
• W4296142904 cites W2621835653 @default.
• W4296142904 cites W2761865284 @default.
• W4296142904 cites W2769938637 @default.
• W4296142904 cites W2788531829 @default.
• W4296142904 cites W2791037596 @default.
• W4296142904 cites W2800131331 @default.
• W4296142904 cites W2883593519 @default.
• W4296142904 cites W2901442087 @default.
• W4296142904 cites W2923195351 @default.
• W4296142904 cites W2927950866 @default.
• W4296142904 cites W2953115794 @default.
• W4296142904 cites W2964698358 @default.
• W4296142904 cites W2969351161 @default.
• W4296142904 cites W2974721962 @default.
• W4296142904 cites W2977689020 @default.
• W4296142904 cites W2980926972 @default.
• W4296142904 cites W2986678676 @default.
• W4296142904 cites W2995975007 @default.
• W4296142904 cites W3007138124 @default.
• W4296142904 cites W3009914364 @default.
• W4296142904 cites W3012768609 @default.
• W4296142904 cites W3017089033 @default.
• W4296142904 cites W3030441098 @default.
• W4296142904 cites W3035004775 @default.
• W4296142904 cites W3036389262 @default.
• W4296142904 cites W3045938749 @default.
• W4296142904 cites W3046824082 @default.
• W4296142904 cites W3087332590 @default.
• W4296142904 cites W3088437725 @default.
• W4296142904 cites W3093172955 @default.
• W4296142904 cites W3103972520 @default.
• W4296142904 cites W3112322633 @default.
• W4296142904 cites W3159995035 @default.
• W4296142904 cites W3166383930 @default.
• W4296142904 cites W3184688397 @default.
• W4296142904 cites W3193612805 @default.
• W4296142904 cites W3198662457 @default.
• W4296142904 cites W3211795092 @default.
• W4296142904 cites W4205762438 @default.
• W4296142904 cites W4212782842 @default.
• W4296142904 cites W4232408031 @default.
• W4296142904 cites W4242081881 @default.

• next