Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296161504> ?p ?o ?g. }
- W4296161504 endingPage "422" @default.
- W4296161504 startingPage "414" @default.
- W4296161504 abstract "The correlation between fatty acids (FAs) and depression is not yet conclusive. This study examined the relationship of FAs composition with the presence and clinical characteristics of first-diagnosed, drug-naïve patients with depression. A total of 139 first-diagnosed, drug-naïve patients with depression and 55 healthy controls (HCs) were included in the cross-sectional study. The levels of erythrocyte membrane FAs were compared and then the correlation between clinical symptoms and fatty acid levels in depression was investigated. Compared to HCs, patients with depression had higher C18:1n9t (z = −2.033, p = 0.042), C20:4n6 (z = −2.104, p = 0.035), C20:3n6 (z = −2.104, p = 0.035) and n-6 polyunsaturated fatty acids (PUFAs) (z = −2.127, p = 0.033), whereas the levels of C18:1n9c (z = −3.348, p = 0.001) were significantly lower. Higher C20:3n6, C20:4n6, C18:1n9t and n-6 PUFAs levels were associated with higher severity of depressive and anxiety symptoms in patients with depression, and the correlation remained after adjusting for the related confounding factors (p < 0.05). Patients with first-diagnosed, drug-naïve depression show abnormal erythrocyte fatty acid composition. Trans fatty acids (TFAs) and n-6 PUFAs levels are closely related to clinical characteristics of depression. This study indicated that increased n-6 PUFAs and TFAs are characteristic changes of first-diagnosed, drug-naïve depression." @default.
- W4296161504 created "2022-09-18" @default.
- W4296161504 creator A5017486387 @default.
- W4296161504 creator A5027475930 @default.
- W4296161504 creator A5028701240 @default.
- W4296161504 creator A5029484872 @default.
- W4296161504 creator A5040386996 @default.
- W4296161504 creator A5046332590 @default.
- W4296161504 creator A5051123510 @default.
- W4296161504 creator A5058117126 @default.
- W4296161504 creator A5058473496 @default.
- W4296161504 creator A5063089557 @default.
- W4296161504 creator A5078094295 @default.
- W4296161504 date "2022-12-01" @default.
- W4296161504 modified "2023-09-23" @default.
- W4296161504 title "Abnormal erythrocyte fatty acid composition in first-diagnosed, drug-naïve patients with depression" @default.
- W4296161504 cites W1572903481 @default.
- W4296161504 cites W1971091197 @default.
- W4296161504 cites W1989322509 @default.
- W4296161504 cites W1991180159 @default.
- W4296161504 cites W1998558885 @default.
- W4296161504 cites W2003494755 @default.
- W4296161504 cites W2004415631 @default.
- W4296161504 cites W2004754261 @default.
- W4296161504 cites W2017367404 @default.
- W4296161504 cites W2022654707 @default.
- W4296161504 cites W2029191095 @default.
- W4296161504 cites W2034040607 @default.
- W4296161504 cites W2043298087 @default.
- W4296161504 cites W2053482696 @default.
- W4296161504 cites W2066857994 @default.
- W4296161504 cites W2076461358 @default.
- W4296161504 cites W2096568900 @default.
- W4296161504 cites W2113969989 @default.
- W4296161504 cites W2121030518 @default.
- W4296161504 cites W2121371688 @default.
- W4296161504 cites W2123374151 @default.
- W4296161504 cites W2124504374 @default.
- W4296161504 cites W2140409786 @default.
- W4296161504 cites W2161901125 @default.
- W4296161504 cites W2297518964 @default.
- W4296161504 cites W2418619565 @default.
- W4296161504 cites W2553834538 @default.
- W4296161504 cites W2592582363 @default.
- W4296161504 cites W2621190740 @default.
- W4296161504 cites W2750081075 @default.
- W4296161504 cites W2763290908 @default.
- W4296161504 cites W2782447188 @default.
- W4296161504 cites W2792728053 @default.
- W4296161504 cites W2801224684 @default.
- W4296161504 cites W2817495207 @default.
- W4296161504 cites W2887187858 @default.
- W4296161504 cites W2892119394 @default.
- W4296161504 cites W2914652359 @default.
- W4296161504 cites W2942264351 @default.
- W4296161504 cites W3000645179 @default.
- W4296161504 cites W3039203990 @default.
- W4296161504 cites W3045967062 @default.
- W4296161504 cites W3092306005 @default.
- W4296161504 cites W3110780002 @default.
- W4296161504 cites W3124217197 @default.
- W4296161504 cites W3165182477 @default.
- W4296161504 cites W3184324295 @default.
- W4296161504 cites W4214538169 @default.
- W4296161504 doi "https://doi.org/10.1016/j.jad.2022.09.023" @default.
- W4296161504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36113689" @default.
- W4296161504 hasPublicationYear "2022" @default.
- W4296161504 type Work @default.
- W4296161504 citedByCount "2" @default.
- W4296161504 countsByYear W42961615042023 @default.
- W4296161504 crossrefType "journal-article" @default.
- W4296161504 hasAuthorship W4296161504A5017486387 @default.
- W4296161504 hasAuthorship W4296161504A5027475930 @default.
- W4296161504 hasAuthorship W4296161504A5028701240 @default.
- W4296161504 hasAuthorship W4296161504A5029484872 @default.
- W4296161504 hasAuthorship W4296161504A5040386996 @default.
- W4296161504 hasAuthorship W4296161504A5046332590 @default.
- W4296161504 hasAuthorship W4296161504A5051123510 @default.
- W4296161504 hasAuthorship W4296161504A5058117126 @default.
- W4296161504 hasAuthorship W4296161504A5058473496 @default.
- W4296161504 hasAuthorship W4296161504A5063089557 @default.
- W4296161504 hasAuthorship W4296161504A5078094295 @default.
- W4296161504 hasConcept C118552586 @default.
- W4296161504 hasConcept C126322002 @default.
- W4296161504 hasConcept C134018914 @default.
- W4296161504 hasConcept C139719470 @default.
- W4296161504 hasConcept C162324750 @default.
- W4296161504 hasConcept C185592680 @default.
- W4296161504 hasConcept C19038510 @default.
- W4296161504 hasConcept C2776867660 @default.
- W4296161504 hasConcept C2777090001 @default.
- W4296161504 hasConcept C2780035454 @default.
- W4296161504 hasConcept C543025807 @default.
- W4296161504 hasConcept C55493867 @default.
- W4296161504 hasConcept C558461103 @default.
- W4296161504 hasConcept C71924100 @default.
- W4296161504 hasConcept C77350462 @default.
- W4296161504 hasConcept C90924648 @default.