Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296187639> ?p ?o ?g. }
- W4296187639 endingPage "290" @default.
- W4296187639 startingPage "283" @default.
- W4296187639 abstract "Hypercoagulability is frequently observed in patients with severe coronavirus disease-2019 (COVID-19). Platelets are a favorable target for effectively treating hypercoagulability in COVID-19 patients as platelet hyperactivity has also been observed. It is difficult to develop a treatment for COVID-19 that will be effective against all variants and the use of antivirals may not be fully effective against COVID-19 as activated platelets have been detected in patients with COVID-19. Therefore, patients with less severe side effects often turn toward natural remedies. Numerous phytochemicals are being investigated for their potential to treat a variety of illnesses, including cancer and bacterial and viral infections. Natural products have been used to alleviate COVID-19 symptoms. Panax ginseng has potential for managing cardiovascular diseases and could be a treatment for COVID-19 by targeting the coagulation cascade and platelet activation. Using molecular docking, we analyzed the interactions of bioactive chemicals in P. ginseng with important proteins and receptors involved in platelet activation. Furthermore, the SwissADME online tool was used to calculate the pharmacokinetics and drug-likeness properties of the lead compounds of P. ginseng. Dianthramine, deoxyharrtingtonine, and suchilactone were determined to have favorable pharmacokinetic profiles." @default.
- W4296187639 created "2022-09-18" @default.
- W4296187639 creator A5005437747 @default.
- W4296187639 creator A5014986711 @default.
- W4296187639 creator A5042820704 @default.
- W4296187639 creator A5044694771 @default.
- W4296187639 creator A5051656427 @default.
- W4296187639 creator A5068550492 @default.
- W4296187639 date "2023-03-01" @default.
- W4296187639 modified "2023-09-28" @default.
- W4296187639 title "In silico investigation of Panax ginseng lead compounds against COVID-19 associated platelet activation and thromboembolism" @default.
- W4296187639 cites W180853016 @default.
- W4296187639 cites W1886579625 @default.
- W4296187639 cites W1994629334 @default.
- W4296187639 cites W2019472123 @default.
- W4296187639 cites W2038436168 @default.
- W4296187639 cites W2039478311 @default.
- W4296187639 cites W2047204651 @default.
- W4296187639 cites W2052441688 @default.
- W4296187639 cites W2076465777 @default.
- W4296187639 cites W2084318119 @default.
- W4296187639 cites W2095872378 @default.
- W4296187639 cites W2110641306 @default.
- W4296187639 cites W2112998064 @default.
- W4296187639 cites W2130479394 @default.
- W4296187639 cites W2164670366 @default.
- W4296187639 cites W2396930286 @default.
- W4296187639 cites W2593436234 @default.
- W4296187639 cites W2791302101 @default.
- W4296187639 cites W2805993472 @default.
- W4296187639 cites W2898085473 @default.
- W4296187639 cites W2946752329 @default.
- W4296187639 cites W2985142357 @default.
- W4296187639 cites W3015492319 @default.
- W4296187639 cites W3016965546 @default.
- W4296187639 cites W3018010622 @default.
- W4296187639 cites W3025069198 @default.
- W4296187639 cites W3025528269 @default.
- W4296187639 cites W3028981427 @default.
- W4296187639 cites W3036853141 @default.
- W4296187639 cites W3040801404 @default.
- W4296187639 cites W3040890594 @default.
- W4296187639 cites W3041178796 @default.
- W4296187639 cites W3042442225 @default.
- W4296187639 cites W3048962534 @default.
- W4296187639 cites W3082831407 @default.
- W4296187639 cites W3085002149 @default.
- W4296187639 cites W3096640075 @default.
- W4296187639 cites W3103501536 @default.
- W4296187639 cites W3106878713 @default.
- W4296187639 cites W3113573438 @default.
- W4296187639 cites W3115695623 @default.
- W4296187639 cites W3118765686 @default.
- W4296187639 cites W3120117783 @default.
- W4296187639 cites W3129002592 @default.
- W4296187639 cites W3133132602 @default.
- W4296187639 cites W3135531364 @default.
- W4296187639 cites W3160592580 @default.
- W4296187639 cites W3168199895 @default.
- W4296187639 cites W3176797277 @default.
- W4296187639 cites W3182310754 @default.
- W4296187639 cites W3186204100 @default.
- W4296187639 cites W3198809089 @default.
- W4296187639 cites W3201716054 @default.
- W4296187639 cites W3210977006 @default.
- W4296187639 cites W4200394625 @default.
- W4296187639 doi "https://doi.org/10.1016/j.jgr.2022.09.001" @default.
- W4296187639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36160270" @default.
- W4296187639 hasPublicationYear "2023" @default.
- W4296187639 type Work @default.
- W4296187639 citedByCount "2" @default.
- W4296187639 countsByYear W42961876392023 @default.
- W4296187639 crossrefType "journal-article" @default.
- W4296187639 hasAuthorship W4296187639A5005437747 @default.
- W4296187639 hasAuthorship W4296187639A5014986711 @default.
- W4296187639 hasAuthorship W4296187639A5042820704 @default.
- W4296187639 hasAuthorship W4296187639A5044694771 @default.
- W4296187639 hasAuthorship W4296187639A5051656427 @default.
- W4296187639 hasAuthorship W4296187639A5068550492 @default.
- W4296187639 hasBestOaLocation W42961876391 @default.
- W4296187639 hasConcept C104317684 @default.
- W4296187639 hasConcept C112705442 @default.
- W4296187639 hasConcept C126322002 @default.
- W4296187639 hasConcept C142724271 @default.
- W4296187639 hasConcept C203014093 @default.
- W4296187639 hasConcept C204787440 @default.
- W4296187639 hasConcept C2775905019 @default.
- W4296187639 hasConcept C2778382381 @default.
- W4296187639 hasConcept C2779134260 @default.
- W4296187639 hasConcept C2779232237 @default.
- W4296187639 hasConcept C3008058167 @default.
- W4296187639 hasConcept C3018697912 @default.
- W4296187639 hasConcept C41685203 @default.
- W4296187639 hasConcept C42972112 @default.
- W4296187639 hasConcept C524204448 @default.
- W4296187639 hasConcept C55493867 @default.
- W4296187639 hasConcept C556039675 @default.
- W4296187639 hasConcept C71924100 @default.