Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296187718> ?p ?o ?g. }
- W4296187718 endingPage "8" @default.
- W4296187718 startingPage "1" @default.
- W4296187718 abstract "Objective. Although studies indicate that Staphylococcus epidermidis (S. epidermidis) can regulate inflammation and anti-inflammatory cytokines, there is limited evidence supporting their effects on atopic dermatitis (AD). Here, we aimed to investigate the effects and potential mechanism of skin commensal bacteria on the immunity of mice with AD. Methods. Twenty-four female BALB/C mice were selected and divided randomly into 4 groups: normal group, atopic dermatitis model group (AD), atopic dermatitis/substrate group (AD/substrates), and atopic dermatitis/substrates/epidermidis group (AD/S. epidermidis). All the mice were given different ways. After 14 days, their skin conditions were scored, and the serum, ear tissue, and inguinal lymph node tissue were collected and analyzed. Furthermore, the flow cytometry was used to analyze the number of CD4°+°CD25°+°Foxp3°+°Treg in the mouse lymph node tissue. Results. Compared with the AD/substrate group, the mice ear thickness and dermatitis score were significantly reduced in the AD/S. epidermidis group; skin epidermis, acanthosis, the degree of keratinization, inflammatory cell infiltration in the dermis, and the number of mast cells were declined. The serum levels of IgE, IgG1, IgG2a, and TNF-α, IFN-γ, IL-4, and Eotaxin were significantly declined in the AD/S. epidermidis compared with the AD/substrate group. The proportion of CD4°+°CD25°+°Foxp3°+°Treg cells in the lymph node tissue was significantly increased in the AD/S. epidermidis group compared with the AD/substrate group. Conclusion. Staphylococcus epidermidis can regulate mice’s immune balance to alleviate AD-induced skin damage." @default.
- W4296187718 created "2022-09-18" @default.
- W4296187718 creator A5008720623 @default.
- W4296187718 creator A5025942093 @default.
- W4296187718 creator A5032314861 @default.
- W4296187718 creator A5077716269 @default.
- W4296187718 creator A5086595203 @default.
- W4296187718 date "2022-09-17" @default.
- W4296187718 modified "2023-10-17" @default.
- W4296187718 title "Skin Commensal Bacteria Modulates the Immune Balance of Mice to Alleviate Atopic Dermatitis-Induced Damage" @default.
- W4296187718 cites W1527957830 @default.
- W4296187718 cites W1783260908 @default.
- W4296187718 cites W1971065236 @default.
- W4296187718 cites W1974004014 @default.
- W4296187718 cites W1976327936 @default.
- W4296187718 cites W1978980985 @default.
- W4296187718 cites W1982386486 @default.
- W4296187718 cites W2039756366 @default.
- W4296187718 cites W2046318425 @default.
- W4296187718 cites W2047885502 @default.
- W4296187718 cites W2056207075 @default.
- W4296187718 cites W2060130170 @default.
- W4296187718 cites W2066989460 @default.
- W4296187718 cites W2067637397 @default.
- W4296187718 cites W2080703172 @default.
- W4296187718 cites W2086163430 @default.
- W4296187718 cites W2118630839 @default.
- W4296187718 cites W2138526275 @default.
- W4296187718 cites W2141649011 @default.
- W4296187718 cites W2146050608 @default.
- W4296187718 cites W2148226248 @default.
- W4296187718 cites W2157364629 @default.
- W4296187718 cites W2158220608 @default.
- W4296187718 cites W2160317538 @default.
- W4296187718 cites W2162819001 @default.
- W4296187718 cites W2165676713 @default.
- W4296187718 cites W2290475350 @default.
- W4296187718 cites W2298124544 @default.
- W4296187718 cites W2346851822 @default.
- W4296187718 cites W2520198258 @default.
- W4296187718 cites W2590317180 @default.
- W4296187718 cites W2620852772 @default.
- W4296187718 cites W2730427050 @default.
- W4296187718 cites W2749220992 @default.
- W4296187718 cites W2753467244 @default.
- W4296187718 cites W2778336362 @default.
- W4296187718 cites W2789418804 @default.
- W4296187718 cites W2796738742 @default.
- W4296187718 cites W2896385011 @default.
- W4296187718 cites W2916655765 @default.
- W4296187718 cites W2995923396 @default.
- W4296187718 cites W3039020657 @default.
- W4296187718 cites W4230355606 @default.
- W4296187718 cites W4280518980 @default.
- W4296187718 doi "https://doi.org/10.1155/2022/4731675" @default.
- W4296187718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36164402" @default.
- W4296187718 hasPublicationYear "2022" @default.
- W4296187718 type Work @default.
- W4296187718 citedByCount "0" @default.
- W4296187718 crossrefType "journal-article" @default.
- W4296187718 hasAuthorship W4296187718A5008720623 @default.
- W4296187718 hasAuthorship W4296187718A5025942093 @default.
- W4296187718 hasAuthorship W4296187718A5032314861 @default.
- W4296187718 hasAuthorship W4296187718A5077716269 @default.
- W4296187718 hasAuthorship W4296187718A5086595203 @default.
- W4296187718 hasBestOaLocation W42961877181 @default.
- W4296187718 hasConcept C142724271 @default.
- W4296187718 hasConcept C203014093 @default.
- W4296187718 hasConcept C2776090121 @default.
- W4296187718 hasConcept C2777949923 @default.
- W4296187718 hasConcept C2778329239 @default.
- W4296187718 hasConcept C2779489039 @default.
- W4296187718 hasConcept C2779720271 @default.
- W4296187718 hasConcept C2779727006 @default.
- W4296187718 hasConcept C523546767 @default.
- W4296187718 hasConcept C54355233 @default.
- W4296187718 hasConcept C71924100 @default.
- W4296187718 hasConcept C79484868 @default.
- W4296187718 hasConcept C86803240 @default.
- W4296187718 hasConcept C8891405 @default.
- W4296187718 hasConceptScore W4296187718C142724271 @default.
- W4296187718 hasConceptScore W4296187718C203014093 @default.
- W4296187718 hasConceptScore W4296187718C2776090121 @default.
- W4296187718 hasConceptScore W4296187718C2777949923 @default.
- W4296187718 hasConceptScore W4296187718C2778329239 @default.
- W4296187718 hasConceptScore W4296187718C2779489039 @default.
- W4296187718 hasConceptScore W4296187718C2779720271 @default.
- W4296187718 hasConceptScore W4296187718C2779727006 @default.
- W4296187718 hasConceptScore W4296187718C523546767 @default.
- W4296187718 hasConceptScore W4296187718C54355233 @default.
- W4296187718 hasConceptScore W4296187718C71924100 @default.
- W4296187718 hasConceptScore W4296187718C79484868 @default.
- W4296187718 hasConceptScore W4296187718C86803240 @default.
- W4296187718 hasConceptScore W4296187718C8891405 @default.
- W4296187718 hasLocation W42961877181 @default.
- W4296187718 hasLocation W42961877182 @default.
- W4296187718 hasLocation W42961877183 @default.
- W4296187718 hasOpenAccess W4296187718 @default.