Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296236064> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4296236064 abstract "Abstract Although constipation is a common non-motor symptom in patients with amyotrophic lateral sclerosis (ALS), it is poorly valued. Moreover, there is a bidirectional effect between constipation and neuropsychiatric and sleep disturbances. Thus, these symptoms are better treated simultaneously. Therefore, this study aimed to develop and validate a model for predicting the risk of constipation in ALS patients, to help clinicians identify and treat constipation early. Data of 118 ALS admissions from an observational prospective cohort, were analyzed. Demographic data as well as related scale scores were obtained. The LASSO regression model was used to select factors. Multivariate logistic regression analysis revealed age, family history of constipation, total ALSFRS-R score, site of onset, total PSQI score, and depressed, were identified as significant predictors of the risk of constipation in ALS patients. The prediction model was validated to have good accuracy (Hosmer–Lemeshow test: χ 2 = 11.11, P > 0.05) and discrimination (AUC = 0.856, 95% CI: 0.784–0.928). DCA and CIC showed that the nomogram model had excellent clinical performance. In brief, a web-based ALS constipation risk calculator with good predictive performance was constructed to identify patients at high risk of constipation and to allow early intervention in a clinical context." @default.
- W4296236064 created "2022-09-18" @default.
- W4296236064 creator A5022526821 @default.
- W4296236064 creator A5037641781 @default.
- W4296236064 creator A5053257075 @default.
- W4296236064 creator A5058126365 @default.
- W4296236064 creator A5076863688 @default.
- W4296236064 creator A5077604645 @default.
- W4296236064 creator A5081675173 @default.
- W4296236064 creator A5085028455 @default.
- W4296236064 date "2022-09-09" @default.
- W4296236064 modified "2023-10-18" @default.
- W4296236064 title "Development and Validation of a Dynamic Risk Prediction System for Constipation in Patients with Amyotrophic Lateral Sclerosis" @default.
- W4296236064 cites W1993623582 @default.
- W4296236064 cites W2003847460 @default.
- W4296236064 cites W2019489381 @default.
- W4296236064 cites W2020424086 @default.
- W4296236064 cites W2067954627 @default.
- W4296236064 cites W2070315197 @default.
- W4296236064 cites W2075817276 @default.
- W4296236064 cites W2082072411 @default.
- W4296236064 cites W2111180320 @default.
- W4296236064 cites W2112055842 @default.
- W4296236064 cites W2140365002 @default.
- W4296236064 cites W2157825442 @default.
- W4296236064 cites W2166281097 @default.
- W4296236064 cites W2333706939 @default.
- W4296236064 cites W2516398766 @default.
- W4296236064 cites W2520360089 @default.
- W4296236064 cites W2570409231 @default.
- W4296236064 cites W2588074340 @default.
- W4296236064 cites W2807893370 @default.
- W4296236064 cites W2870333966 @default.
- W4296236064 cites W2890840903 @default.
- W4296236064 cites W2987715292 @default.
- W4296236064 cites W3162151658 @default.
- W4296236064 cites W3166463621 @default.
- W4296236064 cites W3217309048 @default.
- W4296236064 cites W4210981417 @default.
- W4296236064 doi "https://doi.org/10.21203/rs.3.rs-2030390/v1" @default.
- W4296236064 hasPublicationYear "2022" @default.
- W4296236064 type Work @default.
- W4296236064 citedByCount "0" @default.
- W4296236064 crossrefType "posted-content" @default.
- W4296236064 hasAuthorship W4296236064A5022526821 @default.
- W4296236064 hasAuthorship W4296236064A5037641781 @default.
- W4296236064 hasAuthorship W4296236064A5053257075 @default.
- W4296236064 hasAuthorship W4296236064A5058126365 @default.
- W4296236064 hasAuthorship W4296236064A5076863688 @default.
- W4296236064 hasAuthorship W4296236064A5077604645 @default.
- W4296236064 hasAuthorship W4296236064A5081675173 @default.
- W4296236064 hasAuthorship W4296236064A5085028455 @default.
- W4296236064 hasBestOaLocation W42962360641 @default.
- W4296236064 hasConcept C126322002 @default.
- W4296236064 hasConcept C151730666 @default.
- W4296236064 hasConcept C151956035 @default.
- W4296236064 hasConcept C1862650 @default.
- W4296236064 hasConcept C2779134260 @default.
- W4296236064 hasConcept C2779343474 @default.
- W4296236064 hasConcept C2780596555 @default.
- W4296236064 hasConcept C2781112942 @default.
- W4296236064 hasConcept C34626388 @default.
- W4296236064 hasConcept C71924100 @default.
- W4296236064 hasConcept C72563966 @default.
- W4296236064 hasConcept C86803240 @default.
- W4296236064 hasConceptScore W4296236064C126322002 @default.
- W4296236064 hasConceptScore W4296236064C151730666 @default.
- W4296236064 hasConceptScore W4296236064C151956035 @default.
- W4296236064 hasConceptScore W4296236064C1862650 @default.
- W4296236064 hasConceptScore W4296236064C2779134260 @default.
- W4296236064 hasConceptScore W4296236064C2779343474 @default.
- W4296236064 hasConceptScore W4296236064C2780596555 @default.
- W4296236064 hasConceptScore W4296236064C2781112942 @default.
- W4296236064 hasConceptScore W4296236064C34626388 @default.
- W4296236064 hasConceptScore W4296236064C71924100 @default.
- W4296236064 hasConceptScore W4296236064C72563966 @default.
- W4296236064 hasConceptScore W4296236064C86803240 @default.
- W4296236064 hasLocation W42962360641 @default.
- W4296236064 hasOpenAccess W4296236064 @default.
- W4296236064 hasPrimaryLocation W42962360641 @default.
- W4296236064 hasRelatedWork W2000156804 @default.
- W4296236064 hasRelatedWork W2120603712 @default.
- W4296236064 hasRelatedWork W2168316764 @default.
- W4296236064 hasRelatedWork W2603773853 @default.
- W4296236064 hasRelatedWork W3030363321 @default.
- W4296236064 hasRelatedWork W3190029335 @default.
- W4296236064 hasRelatedWork W3210066426 @default.
- W4296236064 hasRelatedWork W4206662977 @default.
- W4296236064 hasRelatedWork W4285731224 @default.
- W4296236064 hasRelatedWork W4306247841 @default.
- W4296236064 isParatext "false" @default.
- W4296236064 isRetracted "false" @default.
- W4296236064 workType "article" @default.