FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296239009> ?p ?o ?g. }

• W4296239009 endingPage "554" @default.
• W4296239009 startingPage "545" @default.
• W4296239009 abstract "Several computational studies have been undertaken to explore the Ca2+-induced Ca2+ release (CICR) events in cardiac myocytes and along with experimental studies it has given us invaluable insight into the mechanism of CICR from spark/blink initiation to termination and regulation, and their interplay under normal and pathological conditions. The computational modelling of this mechanism has mainly been investigated using coupled differential equations (DEs). However, there is a lack of computational investigation into (1) how the different formulation of coupled DEs capture the Ca2+ movement in the cytosol and sarcoplasmic reticulum (SR), (2) the buffer and dye inclusion in both compartments, and (3) the effect of buffer and dye properties on the calcium behaviour. This work is set out to explore (1) the effect of different coupled formulation of DEs on spark/blink occurrence, (2) the inclusion of improved sarcoplasmic buffering properties, and (3) the effects of cytosolic and sarcoplasmic dye and buffer properties on Ca2+ movement. The simulation results show large discrepancies between different formulations of the governing equations. Additionally, extension of the model to include sarcoplasmic buffering properties show normalised fluorescent dye profiles to be in good agreement with experimental and amongst its one- and two-dimensional representations." @default.
• W4296239009 created "2022-09-18" @default.
• W4296239009 creator A5031159238 @default.
• W4296239009 date "2022-09-18" @default.
• W4296239009 modified "2023-09-26" @default.
• W4296239009 title "A stochastic mathematical model for coupling the cytosolic and sarcoplasmic calcium movements in diseased cardiac myocytes" @default.
• W4296239009 cites W1975522766 @default.
• W4296239009 cites W1988385848 @default.
• W4296239009 cites W2006237744 @default.
• W4296239009 cites W2013798123 @default.
• W4296239009 cites W2021647551 @default.
• W4296239009 cites W2023239608 @default.
• W4296239009 cites W2030111468 @default.
• W4296239009 cites W2030295605 @default.
• W4296239009 cites W2050553914 @default.
• W4296239009 cites W2055962432 @default.
• W4296239009 cites W2070540757 @default.
• W4296239009 cites W2088264606 @default.
• W4296239009 cites W2088413933 @default.
• W4296239009 cites W2099886455 @default.
• W4296239009 cites W2105458107 @default.
• W4296239009 cites W2123443387 @default.
• W4296239009 cites W2126552871 @default.
• W4296239009 cites W2137822235 @default.
• W4296239009 cites W2151996073 @default.
• W4296239009 cites W2170815151 @default.
• W4296239009 cites W2563718045 @default.
• W4296239009 cites W2788512453 @default.
• W4296239009 cites W2794545322 @default.
• W4296239009 cites W2800315289 @default.
• W4296239009 cites W2907253669 @default.
• W4296239009 cites W2921081685 @default.
• W4296239009 cites W4247121563 @default.
• W4296239009 cites W1978339676 @default.
• W4296239009 cites W640936341 @default.
• W4296239009 doi "https://doi.org/10.1007/s00249-022-01617-w" @default.
• W4296239009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36117233" @default.
• W4296239009 hasPublicationYear "2022" @default.
• W4296239009 type Work @default.
• W4296239009 citedByCount "0" @default.
• W4296239009 crossrefType "journal-article" @default.
• W4296239009 hasAuthorship W4296239009A5031159238 @default.
• W4296239009 hasBestOaLocation W42962390091 @default.
• W4296239009 hasConcept C12554922 @default.
• W4296239009 hasConcept C131584629 @default.
• W4296239009 hasConcept C139966638 @default.
• W4296239009 hasConcept C158617107 @default.
• W4296239009 hasConcept C178790620 @default.
• W4296239009 hasConcept C181199279 @default.
• W4296239009 hasConcept C185592680 @default.
• W4296239009 hasConcept C186060115 @default.
• W4296239009 hasConcept C191897082 @default.
• W4296239009 hasConcept C192562407 @default.
• W4296239009 hasConcept C199360897 @default.
• W4296239009 hasConcept C207200792 @default.
• W4296239009 hasConcept C2781215313 @default.
• W4296239009 hasConcept C41008148 @default.
• W4296239009 hasConcept C519063684 @default.
• W4296239009 hasConcept C55493867 @default.
• W4296239009 hasConcept C86803240 @default.
• W4296239009 hasConcept C95444343 @default.
• W4296239009 hasConcept C98539663 @default.
• W4296239009 hasConceptScore W4296239009C12554922 @default.
• W4296239009 hasConceptScore W4296239009C131584629 @default.
• W4296239009 hasConceptScore W4296239009C139966638 @default.
• W4296239009 hasConceptScore W4296239009C158617107 @default.
• W4296239009 hasConceptScore W4296239009C178790620 @default.
• W4296239009 hasConceptScore W4296239009C181199279 @default.
• W4296239009 hasConceptScore W4296239009C185592680 @default.
• W4296239009 hasConceptScore W4296239009C186060115 @default.
• W4296239009 hasConceptScore W4296239009C191897082 @default.
• W4296239009 hasConceptScore W4296239009C192562407 @default.
• W4296239009 hasConceptScore W4296239009C199360897 @default.
• W4296239009 hasConceptScore W4296239009C207200792 @default.
• W4296239009 hasConceptScore W4296239009C2781215313 @default.
• W4296239009 hasConceptScore W4296239009C41008148 @default.
• W4296239009 hasConceptScore W4296239009C519063684 @default.
• W4296239009 hasConceptScore W4296239009C55493867 @default.
• W4296239009 hasConceptScore W4296239009C86803240 @default.
• W4296239009 hasConceptScore W4296239009C95444343 @default.
• W4296239009 hasConceptScore W4296239009C98539663 @default.
• W4296239009 hasIssue "7-8" @default.
• W4296239009 hasLocation W42962390091 @default.
• W4296239009 hasLocation W42962390092 @default.
• W4296239009 hasLocation W42962390093 @default.
• W4296239009 hasLocation W42962390094 @default.
• W4296239009 hasOpenAccess W4296239009 @default.
• W4296239009 hasPrimaryLocation W42962390091 @default.
• W4296239009 hasRelatedWork W154292401 @default.
• W4296239009 hasRelatedWork W2024489118 @default.
• W4296239009 hasRelatedWork W2070228801 @default.
• W4296239009 hasRelatedWork W2071225392 @default.
• W4296239009 hasRelatedWork W2089232336 @default.
• W4296239009 hasRelatedWork W2138310843 @default.
• W4296239009 hasRelatedWork W2156876238 @default.
• W4296239009 hasRelatedWork W2323602985 @default.
• W4296239009 hasRelatedWork W2438654850 @default.
• W4296239009 hasRelatedWork W2477008679 @default.

• next