FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296324698> ?p ?o ?g. }

• W4296324698 endingPage "1033" @default.
• W4296324698 startingPage "1023" @default.
• W4296324698 abstract "Context The establishment of pregnancy in cows requires uterine activity regulation of the main Hippo signalling effector yes-associated protein 1 (YAP). It remains unknown (1) how YAP activity at the corpus luteum (CL) correlates with early pregnancy-related events in ruminants; and (2) if YAP activity in the uterus and CL can be affected by metabolic disorders that may lead to pregnancy failure in ruminants. Aims and methods To determine the effect of early pregnancy on total and phospho-YAP expression and its transcriptional activity in the CL, we compared non-pregnant vs pregnant ewes. To understand the YAP activity dysregulation with disorders that may result in pregnancy loss, we induced negative energy balance in pregnant ewes. Key results and conclusions Our main results indicate that early pregnancy alters the expression and activity patterns of YAP in the ovine CL but not in the endometrium. In addition, while our NEB-induced model fails to alter YAP activity at the endometrium level, we found that fasting during the first but not second week of pregnancy affects YAP activity in the CL of pregnant ewes. Implications The data presented herein provide considerable insight into the activity of a signalling pathway that may be a key player in pregnancy recognition and establishment in ewes." @default.
• W4296324698 created "2022-09-20" @default.
• W4296324698 creator A5007530672 @default.
• W4296324698 creator A5019661974 @default.
• W4296324698 creator A5024178669 @default.
• W4296324698 creator A5044970482 @default.
• W4296324698 creator A5046450521 @default.
• W4296324698 creator A5048440439 @default.
• W4296324698 creator A5054234470 @default.
• W4296324698 creator A5055299856 @default.
• W4296324698 creator A5055522762 @default.
• W4296324698 creator A5063753364 @default.
• W4296324698 creator A5066337407 @default.
• W4296324698 creator A5075907918 @default.
• W4296324698 date "2022-09-19" @default.
• W4296324698 modified "2023-10-16" @default.
• W4296324698 title "Energy balance and hippo effector activity in endometrium and corpus luteum of early pregnant ewes" @default.
• W4296324698 cites W1497165801 @default.
• W4296324698 cites W1972728023 @default.
• W4296324698 cites W1974853601 @default.
• W4296324698 cites W1997262211 @default.
• W4296324698 cites W2009816486 @default.
• W4296324698 cites W2024355922 @default.
• W4296324698 cites W2047700858 @default.
• W4296324698 cites W2050712486 @default.
• W4296324698 cites W2060693552 @default.
• W4296324698 cites W2064838927 @default.
• W4296324698 cites W2065978641 @default.
• W4296324698 cites W2086266189 @default.
• W4296324698 cites W2090815000 @default.
• W4296324698 cites W2108244474 @default.
• W4296324698 cites W2121735767 @default.
• W4296324698 cites W2125029777 @default.
• W4296324698 cites W2126861792 @default.
• W4296324698 cites W2140998974 @default.
• W4296324698 cites W2144360582 @default.
• W4296324698 cites W2148056172 @default.
• W4296324698 cites W2165170394 @default.
• W4296324698 cites W2171501785 @default.
• W4296324698 cites W2204433279 @default.
• W4296324698 cites W2223413920 @default.
• W4296324698 cites W2235816290 @default.
• W4296324698 cites W2337665072 @default.
• W4296324698 cites W2541505790 @default.
• W4296324698 cites W2580252491 @default.
• W4296324698 cites W2621864827 @default.
• W4296324698 cites W2765330745 @default.
• W4296324698 cites W2905759718 @default.
• W4296324698 cites W2937891999 @default.
• W4296324698 cites W2945177113 @default.
• W4296324698 cites W2951221347 @default.
• W4296324698 cites W3045670813 @default.
• W4296324698 cites W3119573472 @default.
• W4296324698 cites W4252319456 @default.
• W4296324698 doi "https://doi.org/10.1071/rd22081" @default.
• W4296324698 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36116787" @default.
• W4296324698 hasPublicationYear "2022" @default.
• W4296324698 type Work @default.
• W4296324698 citedByCount "0" @default.
• W4296324698 crossrefType "journal-article" @default.
• W4296324698 hasAuthorship W4296324698A5007530672 @default.
• W4296324698 hasAuthorship W4296324698A5019661974 @default.
• W4296324698 hasAuthorship W4296324698A5024178669 @default.
• W4296324698 hasAuthorship W4296324698A5044970482 @default.
• W4296324698 hasAuthorship W4296324698A5046450521 @default.
• W4296324698 hasAuthorship W4296324698A5048440439 @default.
• W4296324698 hasAuthorship W4296324698A5054234470 @default.
• W4296324698 hasAuthorship W4296324698A5055299856 @default.
• W4296324698 hasAuthorship W4296324698A5055522762 @default.
• W4296324698 hasAuthorship W4296324698A5063753364 @default.
• W4296324698 hasAuthorship W4296324698A5066337407 @default.
• W4296324698 hasAuthorship W4296324698A5075907918 @default.
• W4296324698 hasConcept C126322002 @default.
• W4296324698 hasConcept C134018914 @default.
• W4296324698 hasConcept C151730666 @default.
• W4296324698 hasConcept C172512520 @default.
• W4296324698 hasConcept C1998276 @default.
• W4296324698 hasConcept C2776608385 @default.
• W4296324698 hasConcept C2779066055 @default.
• W4296324698 hasConcept C2779234561 @default.
• W4296324698 hasConcept C2779343474 @default.
• W4296324698 hasConcept C2779742232 @default.
• W4296324698 hasConcept C51785407 @default.
• W4296324698 hasConcept C54355233 @default.
• W4296324698 hasConcept C71924100 @default.
• W4296324698 hasConcept C86803240 @default.
• W4296324698 hasConcept C95444343 @default.
• W4296324698 hasConceptScore W4296324698C126322002 @default.
• W4296324698 hasConceptScore W4296324698C134018914 @default.
• W4296324698 hasConceptScore W4296324698C151730666 @default.
• W4296324698 hasConceptScore W4296324698C172512520 @default.
• W4296324698 hasConceptScore W4296324698C1998276 @default.
• W4296324698 hasConceptScore W4296324698C2776608385 @default.
• W4296324698 hasConceptScore W4296324698C2779066055 @default.
• W4296324698 hasConceptScore W4296324698C2779234561 @default.
• W4296324698 hasConceptScore W4296324698C2779343474 @default.
• W4296324698 hasConceptScore W4296324698C2779742232 @default.
• W4296324698 hasConceptScore W4296324698C51785407 @default.

• next