Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296410449> ?p ?o ?g. }
- W4296410449 abstract "C-N bond formation takes on a critical significance in reactions of organic synthesis, material production and pharmaceutical manufactory. Chan-Lam has proposed a useful methodology to furnish secondary arylamides under mild conditions. However, when chiral sulfinamides serve as the coupling precursors, the Cu-catalyzed coupling reaction is found with low efficacy. Complex side-products are generated under classic conditions. Moreover, it led to the racemization of the coupling product. In this study, an optimized Ni-catalyzed Chan-Lam type coupling conditions were proposed, which resulted in clean conversion from chiral sulfinamides and arylboronic acids to offer N-aryl sulfinamides efficiently and enantioretentively. The trans-N1 ,N2 -dimethylcyclohexane-1,2-diamine was proven as the most efficient ligand. Under the optimized conditions, a series of chiral N-aryl sulfinamides was prepared with high chemical yield without racemization. Furthermore, a plausible and novel mechanism was proposed. Interestingly, the method could efficiently furnish a wide variety of C-X bonds by coupling arylboronic acids with different nucleophiles." @default.
- W4296410449 created "2022-09-20" @default.
- W4296410449 creator A5005674691 @default.
- W4296410449 creator A5011227147 @default.
- W4296410449 creator A5016038041 @default.
- W4296410449 creator A5032447166 @default.
- W4296410449 creator A5040155377 @default.
- W4296410449 creator A5045340124 @default.
- W4296410449 creator A5062744888 @default.
- W4296410449 creator A5068154994 @default.
- W4296410449 creator A5086389098 @default.
- W4296410449 date "2022-10-25" @default.
- W4296410449 modified "2023-10-02" @default.
- W4296410449 title "An Optimized Ni‐catalyzed Chan‐Lam Type Coupling: Enantioretentive Access to Chiral N‐Aryl Sulfinamides" @default.
- W4296410449 cites W1964554012 @default.
- W4296410449 cites W1985213731 @default.
- W4296410449 cites W1986003523 @default.
- W4296410449 cites W1988989384 @default.
- W4296410449 cites W1996768696 @default.
- W4296410449 cites W2033776465 @default.
- W4296410449 cites W2054350485 @default.
- W4296410449 cites W2054953645 @default.
- W4296410449 cites W2075813623 @default.
- W4296410449 cites W2109148395 @default.
- W4296410449 cites W2111400245 @default.
- W4296410449 cites W2114967634 @default.
- W4296410449 cites W2126363023 @default.
- W4296410449 cites W2138423708 @default.
- W4296410449 cites W2143831413 @default.
- W4296410449 cites W2144900664 @default.
- W4296410449 cites W2318012607 @default.
- W4296410449 cites W2330016163 @default.
- W4296410449 cites W2334653559 @default.
- W4296410449 cites W2342695428 @default.
- W4296410449 cites W2407040666 @default.
- W4296410449 cites W2462322978 @default.
- W4296410449 cites W2539894319 @default.
- W4296410449 cites W2593377099 @default.
- W4296410449 cites W2593425309 @default.
- W4296410449 cites W2791734408 @default.
- W4296410449 cites W2909083354 @default.
- W4296410449 cites W2928705310 @default.
- W4296410449 cites W2943593804 @default.
- W4296410449 cites W2949618004 @default.
- W4296410449 cites W2950131200 @default.
- W4296410449 cites W2950937974 @default.
- W4296410449 cites W2952204959 @default.
- W4296410449 cites W2974742065 @default.
- W4296410449 cites W2990559673 @default.
- W4296410449 cites W3015376042 @default.
- W4296410449 cites W3035512057 @default.
- W4296410449 cites W3137462029 @default.
- W4296410449 cites W4248223203 @default.
- W4296410449 cites W4251167437 @default.
- W4296410449 doi "https://doi.org/10.1002/chem.202202190" @default.
- W4296410449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36125783" @default.
- W4296410449 hasPublicationYear "2022" @default.
- W4296410449 type Work @default.
- W4296410449 citedByCount "1" @default.
- W4296410449 countsByYear W42964104492023 @default.
- W4296410449 crossrefType "journal-article" @default.
- W4296410449 hasAuthorship W4296410449A5005674691 @default.
- W4296410449 hasAuthorship W4296410449A5011227147 @default.
- W4296410449 hasAuthorship W4296410449A5016038041 @default.
- W4296410449 hasAuthorship W4296410449A5032447166 @default.
- W4296410449 hasAuthorship W4296410449A5040155377 @default.
- W4296410449 hasAuthorship W4296410449A5045340124 @default.
- W4296410449 hasAuthorship W4296410449A5062744888 @default.
- W4296410449 hasAuthorship W4296410449A5068154994 @default.
- W4296410449 hasAuthorship W4296410449A5086389098 @default.
- W4296410449 hasConcept C116569031 @default.
- W4296410449 hasConcept C134121241 @default.
- W4296410449 hasConcept C146686406 @default.
- W4296410449 hasConcept C161790260 @default.
- W4296410449 hasConcept C170493617 @default.
- W4296410449 hasConcept C178790620 @default.
- W4296410449 hasConcept C178907741 @default.
- W4296410449 hasConcept C185592680 @default.
- W4296410449 hasConcept C191897082 @default.
- W4296410449 hasConcept C192562407 @default.
- W4296410449 hasConcept C21951064 @default.
- W4296410449 hasConcept C2780263894 @default.
- W4296410449 hasConcept C2781076698 @default.
- W4296410449 hasConcept C55493867 @default.
- W4296410449 hasConcept C60002323 @default.
- W4296410449 hasConceptScore W4296410449C116569031 @default.
- W4296410449 hasConceptScore W4296410449C134121241 @default.
- W4296410449 hasConceptScore W4296410449C146686406 @default.
- W4296410449 hasConceptScore W4296410449C161790260 @default.
- W4296410449 hasConceptScore W4296410449C170493617 @default.
- W4296410449 hasConceptScore W4296410449C178790620 @default.
- W4296410449 hasConceptScore W4296410449C178907741 @default.
- W4296410449 hasConceptScore W4296410449C185592680 @default.
- W4296410449 hasConceptScore W4296410449C191897082 @default.
- W4296410449 hasConceptScore W4296410449C192562407 @default.
- W4296410449 hasConceptScore W4296410449C21951064 @default.
- W4296410449 hasConceptScore W4296410449C2780263894 @default.
- W4296410449 hasConceptScore W4296410449C2781076698 @default.
- W4296410449 hasConceptScore W4296410449C55493867 @default.
- W4296410449 hasConceptScore W4296410449C60002323 @default.