Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296479268> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4296479268 abstract "Abstract Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Background Trichophyton benhamiae is a zoophilic dermatophyte, known as one of the causative agents of dermatophytosis. Objectives The purpose of this study was to explore the genotypes of T. benhamiae strains isolated from geographically different areas of Iran and also to evaluate in vitro antifungal susceptibility profile of these strains against seven antifungal drugs. Methods A total of 22 strains of T. benhamiae and 2 strains of T. eriotrephon were isolated from patients with distinct types of dermatophytosis. DNA extraction and amplification of rDNA regions using ITS1 and ITS4 primers were conducted on the isolates. The in vitro antifungal susceptibility of posaconazole (PSC), voriconazole (VRC), itraconazole (ITC), ketoconazole (KET), caspofungin (CAS), terbinafine (TRB) and griseofulvin (GRZ) was evaluated according to CLSI M38-A2 protocol. Results The multiple alignments of the ITS-rDNA sequences of T. benhamiae indicated a mean similarity of 99.5%, with 0-3 interspecies nucleotide differences. The geometric mean (GM) values of minimum inhibitory concentrations (MICs) and minimum effective concentrations (MECs) across the all isolates were respectively: TRB: 0.025 mg/l, PSC: 0.032 mg/l, ITC: 0.050 mg/l, and VRC: 0.059 mg/l with lower values and CAS: 0.31 mg/l, KTZ: 0.56 mg/l, and GRZ: 0.76 mg/l with higher values. Conclusion Diverse ITS sequence types of T. benhamiae were shown in different geographical regions of Iran. The TRB, PSC, and ITC were the most effective drugs against T. benhamiae strains, respectively. Furthermore, in our study, two strains of T. eriotrephon as a scarce dermatophyte species were described." @default.
- W4296479268 created "2022-09-21" @default.
- W4296479268 creator A5000353848 @default.
- W4296479268 creator A5004528920 @default.
- W4296479268 creator A5007255785 @default.
- W4296479268 creator A5010843536 @default.
- W4296479268 creator A5026585783 @default.
- W4296479268 creator A5087860103 @default.
- W4296479268 date "2022-09-01" @default.
- W4296479268 modified "2023-10-01" @default.
- W4296479268 title "P009 Investigation of <i>in vitro</i> antifungal susceptibility testing and genetic diversity of clinical isolates of <i>Trichophyton benhamiae</i> and <i>Trichophyton eriotrephon</i> in Iran" @default.
- W4296479268 doi "https://doi.org/10.1093/mmy/myac072.p009" @default.
- W4296479268 hasPublicationYear "2022" @default.
- W4296479268 type Work @default.
- W4296479268 citedByCount "0" @default.
- W4296479268 crossrefType "journal-article" @default.
- W4296479268 hasAuthorship W4296479268A5000353848 @default.
- W4296479268 hasAuthorship W4296479268A5004528920 @default.
- W4296479268 hasAuthorship W4296479268A5007255785 @default.
- W4296479268 hasAuthorship W4296479268A5010843536 @default.
- W4296479268 hasAuthorship W4296479268A5026585783 @default.
- W4296479268 hasAuthorship W4296479268A5087860103 @default.
- W4296479268 hasBestOaLocation W42964792681 @default.
- W4296479268 hasConcept C176947019 @default.
- W4296479268 hasConcept C2777071850 @default.
- W4296479268 hasConcept C2778236110 @default.
- W4296479268 hasConcept C2778566413 @default.
- W4296479268 hasConcept C2779548794 @default.
- W4296479268 hasConcept C2780402444 @default.
- W4296479268 hasConcept C2780690907 @default.
- W4296479268 hasConcept C2781064554 @default.
- W4296479268 hasConcept C501593827 @default.
- W4296479268 hasConcept C86803240 @default.
- W4296479268 hasConcept C89423630 @default.
- W4296479268 hasConceptScore W4296479268C176947019 @default.
- W4296479268 hasConceptScore W4296479268C2777071850 @default.
- W4296479268 hasConceptScore W4296479268C2778236110 @default.
- W4296479268 hasConceptScore W4296479268C2778566413 @default.
- W4296479268 hasConceptScore W4296479268C2779548794 @default.
- W4296479268 hasConceptScore W4296479268C2780402444 @default.
- W4296479268 hasConceptScore W4296479268C2780690907 @default.
- W4296479268 hasConceptScore W4296479268C2781064554 @default.
- W4296479268 hasConceptScore W4296479268C501593827 @default.
- W4296479268 hasConceptScore W4296479268C86803240 @default.
- W4296479268 hasConceptScore W4296479268C89423630 @default.
- W4296479268 hasIssue "Supplement_1" @default.
- W4296479268 hasLocation W42964792681 @default.
- W4296479268 hasLocation W42964792682 @default.
- W4296479268 hasOpenAccess W4296479268 @default.
- W4296479268 hasPrimaryLocation W42964792681 @default.
- W4296479268 hasRelatedWork W1785913565 @default.
- W4296479268 hasRelatedWork W1977501366 @default.
- W4296479268 hasRelatedWork W2061461461 @default.
- W4296479268 hasRelatedWork W2113307272 @default.
- W4296479268 hasRelatedWork W2138961087 @default.
- W4296479268 hasRelatedWork W2158453720 @default.
- W4296479268 hasRelatedWork W2162215708 @default.
- W4296479268 hasRelatedWork W2619691753 @default.
- W4296479268 hasRelatedWork W2893372710 @default.
- W4296479268 hasRelatedWork W2947304817 @default.
- W4296479268 hasVolume "60" @default.
- W4296479268 isParatext "false" @default.
- W4296479268 isRetracted "false" @default.
- W4296479268 workType "article" @default.