FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296579299> ?p ?o ?g. }

• W4296579299 endingPage "20" @default.
• W4296579299 startingPage "13" @default.
• W4296579299 abstract "Abstract Interspecific comparison of DNA damage can provide information on the relative vulnerability of marine organisms to toxicants that induce oxidative genotoxicity. Hydrogen peroxide (H2O2) is an oxidative toxicant that causes DNA strand breaks and nucleotide oxidation and is used in multiple industries including Atlantic salmon aquaculture to treat infestations of ectoparasitic sea lice. H2O2 (up to 100 mM) can be released into the water after sea lice treatment, with potential consequences of exposure in nontarget marine organisms. The objective of the current study was to measure and compare differences in levels of H2O2-induced oxidative DNA damage in coelomocytes from Scottish sea urchins Echinus esculentus, Paracentrotus lividus, and Psammechinus miliaris. Coelomocytes were exposed to H2O2 (0–50 mM) for 10 min, cell concentration and viability were quantified, and DNA damage was measured by the fast micromethod, an alkaline unwinding DNA method, and the modified fast micromethod with nucleotide-specific enzymes. Cell viability was &gt;92% in all exposures and did not differ from controls. Psammechinus miliaris coelomocytes had the highest oxidative DNA damage with 0.07 ± 0.01, 0.08 ± 0.01, and 0.07 ± 0.01 strand scission factors (mean ± SD) after incubation with phosphate-buffered saline, formamidopyrimidine-DNA glycosylase, and endonuclease-III, respectively, at 50 mM H2O2. Exposures to 0.5 mM H2O2 (100-fold dilution from recommended lice treatment concentration) induced oxidative DNA damage in all three species of sea urchins, suggesting interspecific differences in vulnerabilities to DNA damage and/or DNA repair mechanisms. Understanding impacts of environmental genotoxicants requires understanding species-specific susceptibilities to DNA damage, which can impact long-term stability in sea urchin populations in proximity to aquaculture farms." @default.
• W4296579299 created "2022-09-22" @default.
• W4296579299 creator A5015471410 @default.
• W4296579299 creator A5034390066 @default.
• W4296579299 creator A5044841379 @default.
• W4296579299 creator A5070868121 @default.
• W4296579299 date "2022-09-20" @default.
• W4296579299 modified "2023-10-14" @default.
• W4296579299 title "Interspecific differences in oxidative DNA damage after hydrogen peroxide exposure of sea urchin coelomocytes" @default.
• W4296579299 cites W128816780 @default.
• W4296579299 cites W1965735354 @default.
• W4296579299 cites W1968499584 @default.
• W4296579299 cites W1968952506 @default.
• W4296579299 cites W1971858668 @default.
• W4296579299 cites W1971892168 @default.
• W4296579299 cites W1976609827 @default.
• W4296579299 cites W1983155817 @default.
• W4296579299 cites W1986941063 @default.
• W4296579299 cites W1990510480 @default.
• W4296579299 cites W1991004817 @default.
• W4296579299 cites W1996253097 @default.
• W4296579299 cites W2001514887 @default.
• W4296579299 cites W2003282170 @default.
• W4296579299 cites W2010282985 @default.
• W4296579299 cites W2019369653 @default.
• W4296579299 cites W2024755124 @default.
• W4296579299 cites W2030167750 @default.
• W4296579299 cites W2030511658 @default.
• W4296579299 cites W2036100452 @default.
• W4296579299 cites W2037916636 @default.
• W4296579299 cites W2038787391 @default.
• W4296579299 cites W204636418 @default.
• W4296579299 cites W2048215347 @default.
• W4296579299 cites W2050739165 @default.
• W4296579299 cites W2060599262 @default.
• W4296579299 cites W2063326972 @default.
• W4296579299 cites W2066309536 @default.
• W4296579299 cites W2072026684 @default.
• W4296579299 cites W2073776346 @default.
• W4296579299 cites W2078567299 @default.
• W4296579299 cites W2085216390 @default.
• W4296579299 cites W2102752109 @default.
• W4296579299 cites W2107569634 @default.
• W4296579299 cites W2110152791 @default.
• W4296579299 cites W2110409902 @default.
• W4296579299 cites W2123114095 @default.
• W4296579299 cites W2131789800 @default.
• W4296579299 cites W2134259738 @default.
• W4296579299 cites W2148437789 @default.
• W4296579299 cites W2157786292 @default.
• W4296579299 cites W2161340431 @default.
• W4296579299 cites W2164961917 @default.
• W4296579299 cites W2258533134 @default.
• W4296579299 cites W2767344139 @default.
• W4296579299 cites W2889369063 @default.
• W4296579299 cites W28941992 @default.
• W4296579299 cites W2901319065 @default.
• W4296579299 cites W2909602463 @default.
• W4296579299 cites W2914923600 @default.
• W4296579299 cites W2962453230 @default.
• W4296579299 cites W2995742916 @default.
• W4296579299 cites W2996628334 @default.
• W4296579299 cites W3016721088 @default.
• W4296579299 cites W3024368215 @default.
• W4296579299 cites W3048649634 @default.
• W4296579299 cites W3088535712 @default.
• W4296579299 cites W4211111038 @default.
• W4296579299 cites W60904970 @default.
• W4296579299 cites W2217477210 @default.
• W4296579299 doi "https://doi.org/10.1093/mutage/geac018" @default.
• W4296579299 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36130095" @default.
• W4296579299 hasPublicationYear "2022" @default.
• W4296579299 type Work @default.
• W4296579299 citedByCount "1" @default.
• W4296579299 countsByYear W42965792992022 @default.
• W4296579299 crossrefType "journal-article" @default.
• W4296579299 hasAuthorship W4296579299A5015471410 @default.
• W4296579299 hasAuthorship W4296579299A5034390066 @default.
• W4296579299 hasAuthorship W4296579299A5044841379 @default.
• W4296579299 hasAuthorship W4296579299A5070868121 @default.
• W4296579299 hasBestOaLocation W42965792991 @default.
• W4296579299 hasConcept C143425029 @default.
• W4296579299 hasConcept C178790620 @default.
• W4296579299 hasConcept C185592680 @default.
• W4296579299 hasConcept C2776151105 @default.
• W4296579299 hasConcept C2776908312 @default.
• W4296579299 hasConcept C2778959862 @default.
• W4296579299 hasConcept C2779436081 @default.
• W4296579299 hasConcept C29730261 @default.
• W4296579299 hasConcept C552990157 @default.
• W4296579299 hasConcept C55493867 @default.
• W4296579299 hasConcept C57600042 @default.
• W4296579299 hasConcept C86803240 @default.
• W4296579299 hasConcept C95444343 @default.
• W4296579299 hasConceptScore W4296579299C143425029 @default.
• W4296579299 hasConceptScore W4296579299C178790620 @default.
• W4296579299 hasConceptScore W4296579299C185592680 @default.
• W4296579299 hasConceptScore W4296579299C2776151105 @default.

• next