Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296618296> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4296618296 endingPage "233" @default.
- W4296618296 startingPage "232" @default.
- W4296618296 abstract "Abstract Vaccenic acid (VA, trans11-18:1) and cis-9, trans11-conjugated linoleic acid (also known as rumenic acid; RA) have received widespread attention as “beneficial” trans fatty acids (TFA) due to their putative health benefits including anti-diabetic properties. Feeding oilseeds (e.g. sunflower seeds or flaxseeds) to cattle given forage-based diets have been shown to enrich their meat and milk fat with VA and RA. However, there is shortage of studies evaluating the health effects of the resulting enriched fat. The objective of the present experiment was to determine the effects of beef fat enriched with VA and RA on parameters related to glucose and insulin tolerance in in high-fat-fed C57BL/6 Mice. Thirty-six 8-week-old male c57/6J mice (25±1.4 g body weight) were randomly assigned for 18 weeks to either a control low fat diet (CLF; 10% total calories from fat), a control high fat diet based on lard (CHF; 45% total calories from fat), or a VA&RA-enriched high fat diet based on flaxseed-fed beef fat (EHF, 45% total calories from fat). Compared with CLF, feeding either CHF or EHF resulted in negative metabolic outcomes associated with high fat diets including adiposity, impaired insulin and glucose tolerances, and hepatic steatosis. However, the EHF diet induced a higher (P < 0.05) liver weight and liver triglyceride content compared with the CHF diet. In addition, the area under the curve for glucose tolerance test (GTT) in EHF mice was higher (P < 0.05) than in CHF group. Collectively, the findings from this study, suggest that feeding beef fat enriched with VA and RA (i.e. EHF) worsens glucose tolerance and liver steatosis in high-fat-fed mice. Additional studies are needed to determine if the adverse effects of EHF on glucose tolerance and liver fat accumulation are related to VA and RA or due to other TFA present in EHF." @default.
- W4296618296 created "2022-09-23" @default.
- W4296618296 creator A5053476430 @default.
- W4296618296 creator A5065221882 @default.
- W4296618296 creator A5074297479 @default.
- W4296618296 creator A5079080434 @default.
- W4296618296 date "2022-09-21" @default.
- W4296618296 modified "2023-09-27" @default.
- W4296618296 title "PSI-4 Beef fat Enriched with Vaccenic Acid and cis-9, Trans11-Conjugated Linoleic Acid Promotes Hepatic Steatosis and Glucose Intolerance in High-fat-fed C57BL/6 Mice" @default.
- W4296618296 doi "https://doi.org/10.1093/jas/skac247.421" @default.
- W4296618296 hasPublicationYear "2022" @default.
- W4296618296 type Work @default.
- W4296618296 citedByCount "0" @default.
- W4296618296 crossrefType "journal-article" @default.
- W4296618296 hasAuthorship W4296618296A5053476430 @default.
- W4296618296 hasAuthorship W4296618296A5065221882 @default.
- W4296618296 hasAuthorship W4296618296A5074297479 @default.
- W4296618296 hasAuthorship W4296618296A5079080434 @default.
- W4296618296 hasBestOaLocation W42966182961 @default.
- W4296618296 hasConcept C126322002 @default.
- W4296618296 hasConcept C134018914 @default.
- W4296618296 hasConcept C185592680 @default.
- W4296618296 hasConcept C2776175330 @default.
- W4296618296 hasConcept C2778163477 @default.
- W4296618296 hasConcept C2778738395 @default.
- W4296618296 hasConcept C2778772119 @default.
- W4296618296 hasConcept C2778913445 @default.
- W4296618296 hasConcept C2779134260 @default.
- W4296618296 hasConcept C2779780233 @default.
- W4296618296 hasConcept C2780556605 @default.
- W4296618296 hasConcept C2780809830 @default.
- W4296618296 hasConcept C31903555 @default.
- W4296618296 hasConcept C40438245 @default.
- W4296618296 hasConcept C543025807 @default.
- W4296618296 hasConcept C55493867 @default.
- W4296618296 hasConcept C71924100 @default.
- W4296618296 hasConcept C86803240 @default.
- W4296618296 hasConceptScore W4296618296C126322002 @default.
- W4296618296 hasConceptScore W4296618296C134018914 @default.
- W4296618296 hasConceptScore W4296618296C185592680 @default.
- W4296618296 hasConceptScore W4296618296C2776175330 @default.
- W4296618296 hasConceptScore W4296618296C2778163477 @default.
- W4296618296 hasConceptScore W4296618296C2778738395 @default.
- W4296618296 hasConceptScore W4296618296C2778772119 @default.
- W4296618296 hasConceptScore W4296618296C2778913445 @default.
- W4296618296 hasConceptScore W4296618296C2779134260 @default.
- W4296618296 hasConceptScore W4296618296C2779780233 @default.
- W4296618296 hasConceptScore W4296618296C2780556605 @default.
- W4296618296 hasConceptScore W4296618296C2780809830 @default.
- W4296618296 hasConceptScore W4296618296C31903555 @default.
- W4296618296 hasConceptScore W4296618296C40438245 @default.
- W4296618296 hasConceptScore W4296618296C543025807 @default.
- W4296618296 hasConceptScore W4296618296C55493867 @default.
- W4296618296 hasConceptScore W4296618296C71924100 @default.
- W4296618296 hasConceptScore W4296618296C86803240 @default.
- W4296618296 hasIssue "Supplement_3" @default.
- W4296618296 hasLocation W42966182961 @default.
- W4296618296 hasOpenAccess W4296618296 @default.
- W4296618296 hasPrimaryLocation W42966182961 @default.
- W4296618296 hasRelatedWork W198538554 @default.
- W4296618296 hasRelatedWork W2020125154 @default.
- W4296618296 hasRelatedWork W2021167873 @default.
- W4296618296 hasRelatedWork W2040001003 @default.
- W4296618296 hasRelatedWork W2183565834 @default.
- W4296618296 hasRelatedWork W2528896110 @default.
- W4296618296 hasRelatedWork W261725901 @default.
- W4296618296 hasRelatedWork W3100988511 @default.
- W4296618296 hasRelatedWork W3157276009 @default.
- W4296618296 hasRelatedWork W4296618296 @default.
- W4296618296 hasVolume "100" @default.
- W4296618296 isParatext "false" @default.
- W4296618296 isRetracted "false" @default.
- W4296618296 workType "article" @default.