Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296690542> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W4296690542 endingPage "403" @default.
- W4296690542 startingPage "397" @default.
- W4296690542 abstract "It is the goal of this research to examine the topical use of non-ionic surfactant for the Formulation and Evaluation of Flavonoid Proniosomes developed for the transdermal delivery of Rutin. The Proniosomal topical gel was prepared using the slurry technique involved with a non-ionic surfactant, Maltodextrin, Cholestrol and Glycerin. A robust design of experiments was used to optimize the various formulation variables. The optimized PG4 formulation was evaluated for entrapment efficiency, SEM, ATR –FTIR, Viscosity, Spreadability, Drug content, in-vitro diffusion study, and stability studies. PG4 formulation showed the highest entrapment efficiency and the higher percent of drug content. Evaluated for viscosity and spreadability which indicated the ratio of span 80: cholesterol demonstrated presenting some fluctuation. The SEM exhibited spherical vesicles and the optimal particle size for proniosome. In vitro drug release was better drug release throughout the process. After 3 months of storage at refrigerator temperatures, the stability in the presence of the percentage drug content of Rutin proniosomal gel formulation 4. There are several benefits to using Span 80 as the nonionic surfactant in these Proniosomal gel formulations, including increased drug accumulation in the different skin layers and increased carrier potential for the topical administration of rutin for the treatment of rheumatoid arthritis." @default.
- W4296690542 created "2022-09-23" @default.
- W4296690542 creator A5012105212 @default.
- W4296690542 creator A5054125593 @default.
- W4296690542 creator A5069778475 @default.
- W4296690542 creator A5070662005 @default.
- W4296690542 date "2022-09-20" @default.
- W4296690542 modified "2023-10-17" @default.
- W4296690542 title "Topical Application Using Non-ionic Surfactant for Formulation and Evaluation of Flavonoid Proniosomes" @default.
- W4296690542 doi "https://doi.org/10.5530/ajbls.2022.11.53" @default.
- W4296690542 hasPublicationYear "2022" @default.
- W4296690542 type Work @default.
- W4296690542 citedByCount "0" @default.
- W4296690542 crossrefType "journal-article" @default.
- W4296690542 hasAuthorship W4296690542A5012105212 @default.
- W4296690542 hasAuthorship W4296690542A5054125593 @default.
- W4296690542 hasAuthorship W4296690542A5069778475 @default.
- W4296690542 hasAuthorship W4296690542A5070662005 @default.
- W4296690542 hasBestOaLocation W42966905421 @default.
- W4296690542 hasConcept C127172972 @default.
- W4296690542 hasConcept C130316041 @default.
- W4296690542 hasConcept C147789679 @default.
- W4296690542 hasConcept C159985019 @default.
- W4296690542 hasConcept C178790620 @default.
- W4296690542 hasConcept C185592680 @default.
- W4296690542 hasConcept C187530423 @default.
- W4296690542 hasConcept C192562407 @default.
- W4296690542 hasConcept C205679159 @default.
- W4296690542 hasConcept C2775963812 @default.
- W4296690542 hasConcept C2777846834 @default.
- W4296690542 hasConcept C2778004101 @default.
- W4296690542 hasConcept C2779587474 @default.
- W4296690542 hasConcept C41625074 @default.
- W4296690542 hasConcept C43617362 @default.
- W4296690542 hasConcept C55493867 @default.
- W4296690542 hasConcept C58226133 @default.
- W4296690542 hasConcept C71924100 @default.
- W4296690542 hasConcept C72918618 @default.
- W4296690542 hasConcept C98274493 @default.
- W4296690542 hasConceptScore W4296690542C127172972 @default.
- W4296690542 hasConceptScore W4296690542C130316041 @default.
- W4296690542 hasConceptScore W4296690542C147789679 @default.
- W4296690542 hasConceptScore W4296690542C159985019 @default.
- W4296690542 hasConceptScore W4296690542C178790620 @default.
- W4296690542 hasConceptScore W4296690542C185592680 @default.
- W4296690542 hasConceptScore W4296690542C187530423 @default.
- W4296690542 hasConceptScore W4296690542C192562407 @default.
- W4296690542 hasConceptScore W4296690542C205679159 @default.
- W4296690542 hasConceptScore W4296690542C2775963812 @default.
- W4296690542 hasConceptScore W4296690542C2777846834 @default.
- W4296690542 hasConceptScore W4296690542C2778004101 @default.
- W4296690542 hasConceptScore W4296690542C2779587474 @default.
- W4296690542 hasConceptScore W4296690542C41625074 @default.
- W4296690542 hasConceptScore W4296690542C43617362 @default.
- W4296690542 hasConceptScore W4296690542C55493867 @default.
- W4296690542 hasConceptScore W4296690542C58226133 @default.
- W4296690542 hasConceptScore W4296690542C71924100 @default.
- W4296690542 hasConceptScore W4296690542C72918618 @default.
- W4296690542 hasConceptScore W4296690542C98274493 @default.
- W4296690542 hasIssue "2" @default.
- W4296690542 hasLocation W42966905421 @default.
- W4296690542 hasOpenAccess W4296690542 @default.
- W4296690542 hasPrimaryLocation W42966905421 @default.
- W4296690542 hasRelatedWork W2048048172 @default.
- W4296690542 hasRelatedWork W2103830394 @default.
- W4296690542 hasRelatedWork W2220448517 @default.
- W4296690542 hasRelatedWork W2571192017 @default.
- W4296690542 hasRelatedWork W2899084033 @default.
- W4296690542 hasRelatedWork W2938615567 @default.
- W4296690542 hasRelatedWork W2967691925 @default.
- W4296690542 hasRelatedWork W3209576372 @default.
- W4296690542 hasRelatedWork W4296690542 @default.
- W4296690542 hasRelatedWork W2155922052 @default.
- W4296690542 hasVolume "11" @default.
- W4296690542 isParatext "false" @default.
- W4296690542 isRetracted "false" @default.
- W4296690542 workType "article" @default.