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• W4296720238 abstract "Abstract Purpose To evaluate the efficacy of a modified Melbourne surgery technique in the treatment of pediatric sagittal synostosis in Chinese population. Methods Thirty-seven sagittal synostosis patients who received surgery in the Children’s Hospital of Nanjing Medical University, Department of Neurosurgery, from January 2015 to January 2020 were analyzed in this study. Here we reconstruct patients’ CT scan images from pre- and post-operation and control groups. Then the data of ICV, CI, anterior skull height, posterior skull height, and biparietal diameter were analyzed using the paired t-test or Wilcoxon matched-pairs signed-ranks test. Result The age of these patients was 28.33±11.54 months. After surgery, in the modified group, the average ICV was enlarged from 1280.95±136.06 to 1431.79±138.17 cm3 (P<0.001), the average CI was increased from 0.70±0.05 to 0.79±0.03 (P<0.001). The average anterior skull height, posterior skull height, and biparietal diameter were change from 99.39±4.52 mm, 83.96±5.97 mm, and 111.67±9.48 mm to 87.89±3.81 mm, 107.47±8.61 mm, and 134.15±7.18 mm after surgery (P<0.001, P=0.03, P<0.001, respectively). The average anterior tilt angle and posterior tilt angle were change from 33.75±3.94° and 25.73±5.25° to 16.56±3.59° and 14.14±3.45° after surgery (P<0.001, P<0.001, respectively). Conclusion The modified Melbourne method is a safe and effective surgical method to treat older children or children with severe sagittal synostosis." @default.
• W4296720238 created "2022-09-23" @default.
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• W4296720238 date "2022-09-21" @default.
• W4296720238 modified "2023-09-30" @default.
• W4296720238 title "Surgical efficacy evaluation of a modified Melbourne method in treatment of sagittal synostosis" @default.
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• W4296720238 doi "https://doi.org/10.21203/rs.3.rs-2063022/v1" @default.
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