FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296768669> ?p ?o ?g. }

• W4296768669 endingPage "550" @default.
• W4296768669 startingPage "541" @default.
• W4296768669 abstract "Analysis of endoplasmic reticulum stress (ERS)-related long noncoding RNAs (LncRNAs) may enable prognostic stratification in patients with head and neck squamous cell carcinoma (HNSCC). This study aimed to comprehensively analyze the ERS-related LncRNAs signature and its effects on the prognosis, tumorigenesis, and tumor immune microenvironment in HNSCC.The transcriptome data of HNSCC were obtained from TCGA. Least absolute shrinkage selection operator algorithm, and multivariate Cox regression were used to screen LncRNAs for the signature construction. Somatic mutation, gene enrichment, and immune infiltration analyses were further performed.458 ERS-related LncRNAs were identified and 55 of which were correlated with HNSCC prognosis. Ten ERS-related LncRNAs were selected to establish a risk prediction signature. When dividing patients into high-risk and low-risk groups by signature score, high-risk group correlated with worse survival rates (hazard ratio = 1.211; 95% confidence interval 1.123-1.306, P < 0.001). The area under the curve was 0.751 and 0.716 in the training and validation cohorts at 3-year. Moreover, high-risk group have increased somatic mutation rates and reduced infiltration abundancy of B cells and CD8+ T cells.The prognostic signature based on ERS-related LncRNAs may serve as a predictor of altered oncogene mutations and immune microenvironment, which provided an insight into the relationship between ERS, LncRNAs, and tumor progression." @default.
• W4296768669 created "2022-09-23" @default.
• W4296768669 creator A5013973657 @default.
• W4296768669 creator A5016154579 @default.
• W4296768669 creator A5019002857 @default.
• W4296768669 creator A5027605871 @default.
• W4296768669 creator A5039414925 @default.
• W4296768669 creator A5040854752 @default.
• W4296768669 creator A5041858122 @default.
• W4296768669 creator A5043148241 @default.
• W4296768669 creator A5044050053 @default.
• W4296768669 creator A5045814483 @default.
• W4296768669 date "2023-04-01" @default.
• W4296768669 modified "2023-09-25" @default.
• W4296768669 title "Prognostic signature of endoplasmic reticulum stress-related long noncoding RNAs in head and neck squamous cell carcinoma: Association with somatic mutation and tumor immune microenvironment" @default.
• W4296768669 cites W1498940267 @default.
• W4296768669 cites W1964662700 @default.
• W4296768669 cites W2058785552 @default.
• W4296768669 cites W2107601804 @default.
• W4296768669 cites W2130085747 @default.
• W4296768669 cites W2130430382 @default.
• W4296768669 cites W2162695817 @default.
• W4296768669 cites W2288651793 @default.
• W4296768669 cites W2347431815 @default.
• W4296768669 cites W2593361213 @default.
• W4296768669 cites W2621111540 @default.
• W4296768669 cites W2749553776 @default.
• W4296768669 cites W2750945356 @default.
• W4296768669 cites W2781901337 @default.
• W4296768669 cites W2795930824 @default.
• W4296768669 cites W2898351328 @default.
• W4296768669 cites W2899969869 @default.
• W4296768669 cites W2945219971 @default.
• W4296768669 cites W2991798444 @default.
• W4296768669 cites W2997271239 @default.
• W4296768669 cites W3010596356 @default.
• W4296768669 cites W3018932210 @default.
• W4296768669 cites W3039946871 @default.
• W4296768669 cites W3083466481 @default.
• W4296768669 cites W3086566870 @default.
• W4296768669 cites W3092610191 @default.
• W4296768669 cites W3093866409 @default.
• W4296768669 cites W3110207354 @default.
• W4296768669 cites W3127753327 @default.
• W4296768669 cites W3128646645 @default.
• W4296768669 cites W3132702868 @default.
• W4296768669 cites W3154153019 @default.
• W4296768669 cites W3164369427 @default.
• W4296768669 cites W3198581600 @default.
• W4296768669 cites W3199356230 @default.
• W4296768669 cites W3211011084 @default.
• W4296768669 cites W3213736506 @default.
• W4296768669 cites W4200623753 @default.
• W4296768669 cites W4210390822 @default.
• W4296768669 cites W4210755784 @default.
• W4296768669 doi "https://doi.org/10.1016/j.jds.2022.09.005" @default.
• W4296768669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37021255" @default.
• W4296768669 hasPublicationYear "2023" @default.
• W4296768669 type Work @default.
• W4296768669 citedByCount "1" @default.
• W4296768669 countsByYear W42967686692023 @default.
• W4296768669 crossrefType "journal-article" @default.
• W4296768669 hasAuthorship W4296768669A5013973657 @default.
• W4296768669 hasAuthorship W4296768669A5016154579 @default.
• W4296768669 hasAuthorship W4296768669A5019002857 @default.
• W4296768669 hasAuthorship W4296768669A5027605871 @default.
• W4296768669 hasAuthorship W4296768669A5039414925 @default.
• W4296768669 hasAuthorship W4296768669A5040854752 @default.
• W4296768669 hasAuthorship W4296768669A5041858122 @default.
• W4296768669 hasAuthorship W4296768669A5043148241 @default.
• W4296768669 hasAuthorship W4296768669A5044050053 @default.
• W4296768669 hasAuthorship W4296768669A5045814483 @default.
• W4296768669 hasBestOaLocation W42967686691 @default.
• W4296768669 hasConcept C104317684 @default.
• W4296768669 hasConcept C121608353 @default.
• W4296768669 hasConcept C126322002 @default.
• W4296768669 hasConcept C134305767 @default.
• W4296768669 hasConcept C143998085 @default.
• W4296768669 hasConcept C150194340 @default.
• W4296768669 hasConcept C162317418 @default.
• W4296768669 hasConcept C203014093 @default.
• W4296768669 hasConcept C207103383 @default.
• W4296768669 hasConcept C2776107976 @default.
• W4296768669 hasConcept C2776530083 @default.
• W4296768669 hasConcept C2776833033 @default.
• W4296768669 hasConcept C44249647 @default.
• W4296768669 hasConcept C502942594 @default.
• W4296768669 hasConcept C54355233 @default.
• W4296768669 hasConcept C555283112 @default.
• W4296768669 hasConcept C71924100 @default.
• W4296768669 hasConcept C86803240 @default.
• W4296768669 hasConcept C8891405 @default.
• W4296768669 hasConceptScore W4296768669C104317684 @default.
• W4296768669 hasConceptScore W4296768669C121608353 @default.
• W4296768669 hasConceptScore W4296768669C126322002 @default.
• W4296768669 hasConceptScore W4296768669C134305767 @default.
• W4296768669 hasConceptScore W4296768669C143998085 @default.
• W4296768669 hasConceptScore W4296768669C150194340 @default.

• next