Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296793523> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4296793523 endingPage "1310" @default.
- W4296793523 startingPage "1310" @default.
- W4296793523 abstract "Background and Objectives: Diesel exhaust particulate matter (DEPM) is an air pollutant that is associated with asthma. In this study, the therapeutic efficacy of Weissella cibaria strains CMU (Chonnam Medical University) and CMS (Chonnam Medical School) 1, together with the drug Synatura, an anti-tussive expectorant, was investigated in a murine asthma model exacerbated by DEPM. Materials and Methods: BALB/c mice were sensitized with ovalbumin (OVA) before intranasal challenge with OVA and DEPM. W. cibaria CMU, CMS1, and Synatura were administered orally for 21 days. Results: Neither Synatura nor W. cibaria strains affected spleen, liver, or lung weights. W. cibaria strains CMU and CMS1 significantly reduced the levels of interleukin (IL)-4, OVA-specific immunoglobulin E (IgE), and total lung collagen in bronchoalveolar lavage fluid (BALF), similar to those with Synatura, regardless of the oral dose concentration (p < 0.05). In addition, the W. cibaria CMU strain significantly alleviated IL-1β, IL-6, IL-12, monocyte chemotactic protein-1, and tumor necrosis factor-α in BALF, whereas the CMS1 strain significantly alleviated IL-10 and IL-12 in BALF (p < 0.05); however, Synatura did not show any statistical efficacy against them (p > 0.05). All concentrations of W. cibaria CMU and low concentrations of W. cibaria CMS1 significantly reduced lung bronchiolar changes and inflammatory cell infiltration. Conclusions: In conclusion, W. cibaria CMU in asthmatic mice showed better efficacy than W. cibaria CMS1 in improving asthma exacerbated by DEPM exposure, as well as better results than pharmaceuticals." @default.
- W4296793523 created "2022-09-24" @default.
- W4296793523 creator A5029762054 @default.
- W4296793523 creator A5034654748 @default.
- W4296793523 creator A5038269576 @default.
- W4296793523 creator A5044457371 @default.
- W4296793523 creator A5045420287 @default.
- W4296793523 creator A5083801077 @default.
- W4296793523 creator A5084221233 @default.
- W4296793523 date "2022-09-19" @default.
- W4296793523 modified "2023-10-01" @default.
- W4296793523 title "Therapeutic Efficacy of Weissella cibaria CMU and CMS1 on Allergic Inflammation Exacerbated by Diesel Exhaust Particulate Matter in a Murine Asthma Model" @default.
- W4296793523 cites W1947221834 @default.
- W4296793523 cites W1979903722 @default.
- W4296793523 cites W1992052519 @default.
- W4296793523 cites W2083753594 @default.
- W4296793523 cites W2123290828 @default.
- W4296793523 cites W2140757940 @default.
- W4296793523 cites W2141566775 @default.
- W4296793523 cites W2142137436 @default.
- W4296793523 cites W2154772518 @default.
- W4296793523 cites W2156645716 @default.
- W4296793523 cites W2331486141 @default.
- W4296793523 cites W2353599515 @default.
- W4296793523 cites W2588544546 @default.
- W4296793523 cites W2606474052 @default.
- W4296793523 cites W2786658869 @default.
- W4296793523 cites W2802000871 @default.
- W4296793523 cites W2893879675 @default.
- W4296793523 cites W2896798862 @default.
- W4296793523 cites W2933648730 @default.
- W4296793523 cites W2947800585 @default.
- W4296793523 cites W3016314854 @default.
- W4296793523 cites W3017511212 @default.
- W4296793523 cites W3022617751 @default.
- W4296793523 cites W3034164116 @default.
- W4296793523 cites W3081895260 @default.
- W4296793523 cites W3086858263 @default.
- W4296793523 cites W3094892031 @default.
- W4296793523 cites W3097910652 @default.
- W4296793523 cites W3137575383 @default.
- W4296793523 cites W3164978551 @default.
- W4296793523 cites W4206744046 @default.
- W4296793523 cites W4221115243 @default.
- W4296793523 cites W4226135618 @default.
- W4296793523 doi "https://doi.org/10.3390/medicina58091310" @default.
- W4296793523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36143987" @default.
- W4296793523 hasPublicationYear "2022" @default.
- W4296793523 type Work @default.
- W4296793523 citedByCount "2" @default.
- W4296793523 countsByYear W42967935232023 @default.
- W4296793523 crossrefType "journal-article" @default.
- W4296793523 hasAuthorship W4296793523A5029762054 @default.
- W4296793523 hasAuthorship W4296793523A5034654748 @default.
- W4296793523 hasAuthorship W4296793523A5038269576 @default.
- W4296793523 hasAuthorship W4296793523A5044457371 @default.
- W4296793523 hasAuthorship W4296793523A5045420287 @default.
- W4296793523 hasAuthorship W4296793523A5083801077 @default.
- W4296793523 hasAuthorship W4296793523A5084221233 @default.
- W4296793523 hasBestOaLocation W42967935231 @default.
- W4296793523 hasConcept C126322002 @default.
- W4296793523 hasConcept C203014093 @default.
- W4296793523 hasConcept C2776042228 @default.
- W4296793523 hasConcept C2776946954 @default.
- W4296793523 hasConcept C2777714996 @default.
- W4296793523 hasConcept C2777961210 @default.
- W4296793523 hasConcept C71924100 @default.
- W4296793523 hasConcept C8891405 @default.
- W4296793523 hasConceptScore W4296793523C126322002 @default.
- W4296793523 hasConceptScore W4296793523C203014093 @default.
- W4296793523 hasConceptScore W4296793523C2776042228 @default.
- W4296793523 hasConceptScore W4296793523C2776946954 @default.
- W4296793523 hasConceptScore W4296793523C2777714996 @default.
- W4296793523 hasConceptScore W4296793523C2777961210 @default.
- W4296793523 hasConceptScore W4296793523C71924100 @default.
- W4296793523 hasConceptScore W4296793523C8891405 @default.
- W4296793523 hasFunder F4320322068 @default.
- W4296793523 hasIssue "9" @default.
- W4296793523 hasLocation W42967935231 @default.
- W4296793523 hasLocation W42967935232 @default.
- W4296793523 hasLocation W42967935233 @default.
- W4296793523 hasLocation W42967935234 @default.
- W4296793523 hasOpenAccess W4296793523 @default.
- W4296793523 hasPrimaryLocation W42967935231 @default.
- W4296793523 hasRelatedWork W1768537334 @default.
- W4296793523 hasRelatedWork W2008232926 @default.
- W4296793523 hasRelatedWork W2022645686 @default.
- W4296793523 hasRelatedWork W2029245561 @default.
- W4296793523 hasRelatedWork W2067867776 @default.
- W4296793523 hasRelatedWork W2072212573 @default.
- W4296793523 hasRelatedWork W2171245968 @default.
- W4296793523 hasRelatedWork W3025418004 @default.
- W4296793523 hasRelatedWork W3193869572 @default.
- W4296793523 hasRelatedWork W2416393409 @default.
- W4296793523 hasVolume "58" @default.
- W4296793523 isParatext "false" @default.
- W4296793523 isRetracted "false" @default.
- W4296793523 workType "article" @default.