Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296793558> ?p ?o ?g. }
- W4296793558 abstract "Treatment options with targeted agents have changed the treatment landscape of CLL profoundly. Besides chemoimmunotherapy, treatment regimen approved for frontline therapy include continuous treatment with BTK inhibitors like ibrutinib and acalabrutinib or fixed-duration regimen like venetoclax-obinutuzumab with the approval of venetoclax-ibrutinib to be awaited. Although these agents have usually manageable side effects, toxicities might limit choices for the individual patient. We here discuss latest trial data and propose a treatment algorithm for frontline treatment of CLL according to fitness and relevant genetic risk factors like IGHV mutational status and TP53 aberrations." @default.
- W4296793558 created "2022-09-24" @default.
- W4296793558 creator A5044687687 @default.
- W4296793558 creator A5061682665 @default.
- W4296793558 creator A5070519285 @default.
- W4296793558 date "2022-09-20" @default.
- W4296793558 modified "2023-10-16" @default.
- W4296793558 title "Management of front line chronic lymphocytic leukemia" @default.
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- W4296793558 doi "https://doi.org/10.1002/ajh.26677" @default.
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