FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296793974> ?p ?o ?g. }

• W4296793974 endingPage "253" @default.
• W4296793974 startingPage "245" @default.
• W4296793974 abstract "Purpose. Randomised controlled trials have shown that renal denervation lowers office and ambulatory blood pressure. The aim of the present study was to evaluate whether patients undergoing renal denervation procedure in a real-life setting have a reduction in antihypertensive drug prescription over the subsequent years.Material and methods. Using the healthcare utilisation database of the Lombardy Region (Italy), the 136 patients who, during the period 2011-2016, were prescribed four or more antihypertensive drugs and underwent renal denervation were included in the study cohort. The number and type of antihypertensive drugs were assessed over the year before and during the three-year period after renal denervation.Results. The median age of the patients was 67 years and 68% of them were men. Based on a multisource comorbidity score, about 40% of patients showed a poor or very poor clinical status. Before renal denervation, the majority of the patients were prescribed four or five antihypertensive drugs. The number of drugs decreased after the denervation and reached 55% after three years. Over the same period, patients prescribed six drugs decreased from 18% to 2%. All antihypertensive drugs were less prescribed throughout the post denervation period. Compared to the year before the denervation, after three years prescription of diuretics was reduced by 15%, calcium channel blockers by 21%, ACE-inhibitors by 32%, angiotensin receptor blockers by 22%, beta-blockers by 20%, and alfa-blockers by 30%. Use of antihypertensive drugs exhibited a reduction also in an age, sex, and clinically matched control group with no renal denervation to an extent, however, much lower than in denervated patients (p-value = 0.013).Conclusion. In the real-life setting, patients who underwent renal denervation had a clearcut reduction in antihypertensive drug prescription over the following years.Plain Language SummaryPatients exhibited a reduction in the prescription of antihypertensive drugs during the three years that followed the denervation procedureThe decrease in the number of antihypertensive drugs was marked, started after a relatively short time (six months), and involved all drugs prescribed before the denervationThe number of hospitalisations for a cardiovascular event was similar before and after renal denervationAlbeit blood pressure values were not recorded in our database, all these findings taken together suggest the renal denervation procedure has a favourable influence on blood pressure control and is not associated with an increase in the risk of major cardiovascular complications." @default.
• W4296793974 created "2022-09-24" @default.
• W4296793974 creator A5041210829 @default.
• W4296793974 creator A5044171254 @default.
• W4296793974 creator A5045075334 @default.
• W4296793974 creator A5084756058 @default.
• W4296793974 creator A5089902123 @default.
• W4296793974 date "2022-09-22" @default.
• W4296793974 modified "2023-09-25" @default.
• W4296793974 title "The impact of renal denervation procedure on use of antihypertensive drugs in the real-life setting" @default.
• W4296793974 cites W1583834060 @default.
• W4296793974 cites W1979956481 @default.
• W4296793974 cites W1994487234 @default.
• W4296793974 cites W2008110203 @default.
• W4296793974 cites W205259702 @default.
• W4296793974 cites W2082072583 @default.
• W4296793974 cites W2110123557 @default.
• W4296793974 cites W2115461708 @default.
• W4296793974 cites W2122915712 @default.
• W4296793974 cites W2133088349 @default.
• W4296793974 cites W2138785816 @default.
• W4296793974 cites W2148827677 @default.
• W4296793974 cites W2161246417 @default.
• W4296793974 cites W2167557672 @default.
• W4296793974 cites W2169491483 @default.
• W4296793974 cites W2397519623 @default.
• W4296793974 cites W2748414916 @default.
• W4296793974 cites W2779998178 @default.
• W4296793974 cites W2781049860 @default.
• W4296793974 cites W2803910972 @default.
• W4296793974 cites W2804838656 @default.
• W4296793974 cites W2893074865 @default.
• W4296793974 cites W2894724600 @default.
• W4296793974 cites W2953292043 @default.
• W4296793974 cites W3013841246 @default.
• W4296793974 cites W3034082335 @default.
• W4296793974 cites W3161121126 @default.
• W4296793974 cites W3164868715 @default.
• W4296793974 cites W3171343307 @default.
• W4296793974 cites W3178407368 @default.
• W4296793974 cites W4205483985 @default.
• W4296793974 cites W4225243790 @default.
• W4296793974 doi "https://doi.org/10.1080/08037051.2022.2126345" @default.
• W4296793974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36146925" @default.
• W4296793974 hasPublicationYear "2022" @default.
• W4296793974 type Work @default.
• W4296793974 citedByCount "0" @default.
• W4296793974 crossrefType "journal-article" @default.
• W4296793974 hasAuthorship W4296793974A5041210829 @default.
• W4296793974 hasAuthorship W4296793974A5044171254 @default.
• W4296793974 hasAuthorship W4296793974A5045075334 @default.
• W4296793974 hasAuthorship W4296793974A5084756058 @default.
• W4296793974 hasAuthorship W4296793974A5089902123 @default.
• W4296793974 hasBestOaLocation W42967939741 @default.
• W4296793974 hasConcept C126322002 @default.
• W4296793974 hasConcept C126894567 @default.
• W4296793974 hasConcept C164705383 @default.
• W4296793974 hasConcept C188816634 @default.
• W4296793974 hasConcept C2426938 @default.
• W4296793974 hasConcept C2776805190 @default.
• W4296793974 hasConcept C2779918671 @default.
• W4296793974 hasConcept C2780192228 @default.
• W4296793974 hasConcept C35785553 @default.
• W4296793974 hasConcept C71924100 @default.
• W4296793974 hasConcept C72563966 @default.
• W4296793974 hasConcept C84393581 @default.
• W4296793974 hasConcept C98274493 @default.
• W4296793974 hasConceptScore W4296793974C126322002 @default.
• W4296793974 hasConceptScore W4296793974C126894567 @default.
• W4296793974 hasConceptScore W4296793974C164705383 @default.
• W4296793974 hasConceptScore W4296793974C188816634 @default.
• W4296793974 hasConceptScore W4296793974C2426938 @default.
• W4296793974 hasConceptScore W4296793974C2776805190 @default.
• W4296793974 hasConceptScore W4296793974C2779918671 @default.
• W4296793974 hasConceptScore W4296793974C2780192228 @default.
• W4296793974 hasConceptScore W4296793974C35785553 @default.
• W4296793974 hasConceptScore W4296793974C71924100 @default.
• W4296793974 hasConceptScore W4296793974C72563966 @default.
• W4296793974 hasConceptScore W4296793974C84393581 @default.
• W4296793974 hasConceptScore W4296793974C98274493 @default.
• W4296793974 hasIssue "1" @default.
• W4296793974 hasLocation W42967939741 @default.
• W4296793974 hasLocation W42967939742 @default.
• W4296793974 hasLocation W42967939743 @default.
• W4296793974 hasOpenAccess W4296793974 @default.
• W4296793974 hasPrimaryLocation W42967939741 @default.
• W4296793974 hasRelatedWork W1976529045 @default.
• W4296793974 hasRelatedWork W2069379005 @default.
• W4296793974 hasRelatedWork W2093345220 @default.
• W4296793974 hasRelatedWork W2094014018 @default.
• W4296793974 hasRelatedWork W2166442548 @default.
• W4296793974 hasRelatedWork W2395552301 @default.
• W4296793974 hasRelatedWork W2415629807 @default.
• W4296793974 hasRelatedWork W2502324469 @default.
• W4296793974 hasRelatedWork W4280519781 @default.
• W4296793974 hasRelatedWork W4280618026 @default.
• W4296793974 hasVolume "31" @default.
• W4296793974 isParatext "false" @default.

• next