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• W4296807337 abstract "The objective of this study was to evaluate the evidence on cost‐effectiveness of pharmacogenetic (PGx)–guided treatment for drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines. A systematic review was conducted using multiple biomedical literature databases from inception to June 2021. Full articles comparing PGx‐guided with nonguided treatment were included for data extraction. Quality of Health Economic Studies (QHES) was used to assess robustness of each study (0–100). Data are reported using descriptive statistics. Of 108 studies evaluating 39 drugs, 77 (71%) showed PGx testing was cost‐effective (CE) ( N = 48) or cost‐saving (CS) ( N = 29); 21 (20%) were not CE; 10 (9%) were uncertain. Clopidogrel had the most articles ( N = 23), of which 22 demonstrated CE or CS, followed by warfarin ( N = 16), of which 7 demonstrated CE or CS. Of 26 studies evaluating human leukocyte antigen (HLA) testing for abacavir ( N = 8), allopurinol ( N = 10), or carbamazepine/phenytoin ( N = 8), 15 demonstrated CE or CS. Nine of 11 antidepressant articles demonstrated CE or CS. The median QHES score reflected high‐quality studies (91; range 48–100). Most studies evaluating cost‐effectiveness favored PGx testing. Limited data exist on cost‐effectiveness of preemptive and multigene testing across disease states." @default.
• W4296807337 created "2022-09-24" @default.
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• W4296807337 date "2022-10-09" @default.
• W4296807337 modified "2023-10-15" @default.
• W4296807337 title "Cost Effectiveness of Pharmacogenetic Testing for Drugs with Clinical Pharmacogenetics Implementation Consortium (<scp>CPIC</scp>) Guidelines: A Systematic Review" @default.
• W4296807337 cites W1487649173 @default.
• W4296807337 cites W1581469242 @default.
• W4296807337 cites W1662226698 @default.
• W4296807337 cites W1723350759 @default.
• W4296807337 cites W1885281724 @default.
• W4296807337 cites W1957277697 @default.
• W4296807337 cites W1967710844 @default.
• W4296807337 cites W1971946342 @default.
• W4296807337 cites W1976315467 @default.
• W4296807337 cites W1981978891 @default.
• W4296807337 cites W1984185385 @default.
• W4296807337 cites W1984954114 @default.
• W4296807337 cites W1987938439 @default.
• W4296807337 cites W1989654054 @default.
• W4296807337 cites W1989868349 @default.
• W4296807337 cites W1989978053 @default.
• W4296807337 cites W2007182242 @default.
• W4296807337 cites W2007836516 @default.
• W4296807337 cites W2009674096 @default.
• W4296807337 cites W2018431503 @default.
• W4296807337 cites W2022967348 @default.
• W4296807337 cites W2025100003 @default.
• W4296807337 cites W2030352776 @default.
• W4296807337 cites W2045776918 @default.
• W4296807337 cites W2049471379 @default.
• W4296807337 cites W2049491341 @default.
• W4296807337 cites W2059533196 @default.
• W4296807337 cites W2062245141 @default.
• W4296807337 cites W2065874658 @default.
• W4296807337 cites W2066113800 @default.
• W4296807337 cites W2067315990 @default.
• W4296807337 cites W2070003774 @default.
• W4296807337 cites W2074634974 @default.
• W4296807337 cites W2077779350 @default.
• W4296807337 cites W2082126453 @default.
• W4296807337 cites W2091242637 @default.
• W4296807337 cites W2102316672 @default.
• W4296807337 cites W2103792822 @default.
• W4296807337 cites W2105178715 @default.
• W4296807337 cites W2108182085 @default.
• W4296807337 cites W2116333054 @default.
• W4296807337 cites W2116356899 @default.
• W4296807337 cites W2117877853 @default.
• W4296807337 cites W2120211131 @default.
• W4296807337 cites W2121373968 @default.
• W4296807337 cites W2130921523 @default.
• W4296807337 cites W2137364748 @default.
• W4296807337 cites W2138017498 @default.
• W4296807337 cites W2138969220 @default.
• W4296807337 cites W2145602800 @default.
• W4296807337 cites W2145890930 @default.
• W4296807337 cites W2149246244 @default.
• W4296807337 cites W2158864490 @default.
• W4296807337 cites W2161620765 @default.
• W4296807337 cites W2162991569 @default.
• W4296807337 cites W2167706426 @default.
• W4296807337 cites W2170468317 @default.
• W4296807337 cites W2171466783 @default.
• W4296807337 cites W2172995811 @default.
• W4296807337 cites W2173347118 @default.
• W4296807337 cites W2174633205 @default.
• W4296807337 cites W2262742005 @default.
• W4296807337 cites W2278631385 @default.
• W4296807337 cites W2281721203 @default.
• W4296807337 cites W2288260410 @default.
• W4296807337 cites W2306473868 @default.
• W4296807337 cites W2324741940 @default.
• W4296807337 cites W2366835925 @default.
• W4296807337 cites W2404851580 @default.
• W4296807337 cites W2411717376 @default.
• W4296807337 cites W2411762199 @default.
• W4296807337 cites W2416740644 @default.
• W4296807337 cites W2418621767 @default.
• W4296807337 cites W2424991464 @default.
• W4296807337 cites W2483809052 @default.
• W4296807337 cites W2538955125 @default.
• W4296807337 cites W2548080299 @default.
• W4296807337 cites W2559816575 @default.
• W4296807337 cites W2570404502 @default.
• W4296807337 cites W2580858561 @default.
• W4296807337 cites W2594351722 @default.
• W4296807337 cites W2598674670 @default.
• W4296807337 cites W2603136056 @default.
• W4296807337 cites W2607472921 @default.
• W4296807337 cites W2735156698 @default.
• W4296807337 cites W2735446982 @default.

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