FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4296809780> ?p ?o ?g. }

• W4296809780 endingPage "e0273071" @default.
• W4296809780 startingPage "e0273071" @default.
• W4296809780 abstract "Dengue infection is the most prevalent mosquito-borne viral infection globally. Concurrently, there has also been an upsurge of non-communicable comorbidities. We aimed to investigate the association between these comorbidities and the development of severe dengue.We performed a retrospective, case-control study involving 117 cases with severe dengue and 351 controls with non-severe dengue; matched according to gender, age (+/- 5 years old), and admission date (+/- 2 weeks). We analyzed the data using conditional odds ratio (cOR) and adjusted conditional odds ratio (AcOR) using univariate and multivariable conditional logistic regression respectively.Six main comorbidities namely obesity, diabetes mellitus, hypertension, hyperlipidemia, chronic pulmonary disease, and ischemic heart disease were observed among cases and controls. Multivariable conditional logistic regression model found only hypertension to be independently associated with the development of severe dengue (ACOR 2.46; 95% CI:1.09-5.53). Among symptoms at presentation, lethargy, vomiting, bleeding manifestations, and abdominal pain were associated with increased odds of severe dengue, although the associations were not statistically significant. Headache (ACOR: 0:32; 95% CI: 0.21-0.51) and skin rash (ACOR: 0.42; 95% CI: 0.22-0.81) were associated with significantly lower odds of severe dengue. Severe dengue patients were also found to have significantly higher white cell count, urea, creatinine, alanine aminotransferase, aspartate aminotransferase, creatine kinase, and lactate dehydrogenase on admission, while platelet and albumin were significantly lower compared to non-severe dengue patients.Our study found a significant association between hypertension and the development of severe dengue in adult patients. For clinical practice, this finding suggests that dengue patients with underlying hypertension warrant closer clinical monitoring for deterioration. The association between significant derangement in various laboratory parameters and severe dengue as shown in this study is in keeping with previous reports. While further substantiation by larger prospective studies will be desirable, this association may serve to inform the dengue triaging process." @default.
• W4296809780 created "2022-09-24" @default.
• W4296809780 creator A5001776640 @default.
• W4296809780 creator A5008423324 @default.
• W4296809780 creator A5024698707 @default.
• W4296809780 creator A5029301986 @default.
• W4296809780 creator A5034643585 @default.
• W4296809780 creator A5034914322 @default.
• W4296809780 creator A5041019746 @default.
• W4296809780 creator A5044452688 @default.
• W4296809780 creator A5048815944 @default.
• W4296809780 creator A5066993844 @default.
• W4296809780 creator A5085663109 @default.
• W4296809780 creator A5089350667 @default.
• W4296809780 creator A5090547234 @default.
• W4296809780 date "2022-09-20" @default.
• W4296809780 modified "2023-09-27" @default.
• W4296809780 title "A double whammy: The association between comorbidities and severe dengue among adult patients—A matched case-control study" @default.
• W4296809780 cites W1483154637 @default.
• W4296809780 cites W1484715519 @default.
• W4296809780 cites W1516017777 @default.
• W4296809780 cites W1549304720 @default.
• W4296809780 cites W1828634901 @default.
• W4296809780 cites W1966461396 @default.
• W4296809780 cites W1983499787 @default.
• W4296809780 cites W1991448459 @default.
• W4296809780 cites W2006816764 @default.
• W4296809780 cites W2016444921 @default.
• W4296809780 cites W2022292268 @default.
• W4296809780 cites W2028860955 @default.
• W4296809780 cites W2029684843 @default.
• W4296809780 cites W2035358721 @default.
• W4296809780 cites W2036766889 @default.
• W4296809780 cites W2038035094 @default.
• W4296809780 cites W2039222823 @default.
• W4296809780 cites W2039420330 @default.
• W4296809780 cites W2052353914 @default.
• W4296809780 cites W2053490656 @default.
• W4296809780 cites W2056274945 @default.
• W4296809780 cites W2066177724 @default.
• W4296809780 cites W2067193640 @default.
• W4296809780 cites W2069959532 @default.
• W4296809780 cites W2105074740 @default.
• W4296809780 cites W2120152186 @default.
• W4296809780 cites W2131999091 @default.
• W4296809780 cites W2142279567 @default.
• W4296809780 cites W2164123970 @default.
• W4296809780 cites W2179138235 @default.
• W4296809780 cites W2226047685 @default.
• W4296809780 cites W2338936985 @default.
• W4296809780 cites W2346811083 @default.
• W4296809780 cites W2400938098 @default.
• W4296809780 cites W2416511226 @default.
• W4296809780 cites W2475005914 @default.
• W4296809780 cites W2737963594 @default.
• W4296809780 cites W2739174192 @default.
• W4296809780 cites W2770874770 @default.
• W4296809780 cites W2786255039 @default.
• W4296809780 cites W2794727186 @default.
• W4296809780 cites W2883275350 @default.
• W4296809780 cites W2950420258 @default.
• W4296809780 cites W3040202395 @default.
• W4296809780 cites W3118570342 @default.
• W4296809780 cites W4211135732 @default.
• W4296809780 cites W2396403346 @default.
• W4296809780 doi "https://doi.org/10.1371/journal.pone.0273071" @default.
• W4296809780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36126060" @default.
• W4296809780 hasPublicationYear "2022" @default.
• W4296809780 type Work @default.
• W4296809780 citedByCount "2" @default.
• W4296809780 countsByYear W42968097802023 @default.
• W4296809780 crossrefType "journal-article" @default.
• W4296809780 hasAuthorship W4296809780A5001776640 @default.
• W4296809780 hasAuthorship W4296809780A5008423324 @default.
• W4296809780 hasAuthorship W4296809780A5024698707 @default.
• W4296809780 hasAuthorship W4296809780A5029301986 @default.
• W4296809780 hasAuthorship W4296809780A5034643585 @default.
• W4296809780 hasAuthorship W4296809780A5034914322 @default.
• W4296809780 hasAuthorship W4296809780A5041019746 @default.
• W4296809780 hasAuthorship W4296809780A5044452688 @default.
• W4296809780 hasAuthorship W4296809780A5048815944 @default.
• W4296809780 hasAuthorship W4296809780A5066993844 @default.
• W4296809780 hasAuthorship W4296809780A5085663109 @default.
• W4296809780 hasAuthorship W4296809780A5089350667 @default.
• W4296809780 hasAuthorship W4296809780A5090547234 @default.
• W4296809780 hasBestOaLocation W42968097801 @default.
• W4296809780 hasConcept C126322002 @default.
• W4296809780 hasConcept C134018914 @default.
• W4296809780 hasConcept C146304588 @default.
• W4296809780 hasConcept C156957248 @default.
• W4296809780 hasConcept C203014093 @default.
• W4296809780 hasConcept C2776009029 @default.
• W4296809780 hasConcept C533803919 @default.
• W4296809780 hasConcept C555293320 @default.
• W4296809780 hasConcept C71924100 @default.
• W4296809780 hasConcept C90924648 @default.
• W4296809780 hasConceptScore W4296809780C126322002 @default.
• W4296809780 hasConceptScore W4296809780C134018914 @default.

• next