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• W4297021495 abstract "Abstract Background and objective: Trichomoniasis is the most common non-viral sexually transmitted infection. One of the methods for diagnosing trichomoniasis is a wet smear test. Propolis has anti-parasitic properties are due to its components, namely tannins, flavonoids, and volatile oils. The present study was performed to compare the effect of a vaginal gel containing propolis extract with that of a metronidazole oral tablet on the wet smear test results in women suffering from trichomoniasis. Material and method: The present clinical trial was performed on 102 married non-pregnant women with trichomoniasis, who were referred to obstetrics and gynecology clinics in Isfahan from September 15 to January 20, 2020. The patients were assigned into two groups of intervention and control randomly. Both groups underwent treatment for 7 days. Wet smear was taken from the patients three times (i.e. initial visit, first follow-up, and second follow-up) and the samples were observed under Carl Zeiss single-lens microscope. Data were analyzed using SPSS (version 20) at a significance level of 0.05. Results: Two groups did not differ significantly in terms of baseline characteristics. In the first post-treatment follow-up, the chance of a negative wet smear test result was 4.41 times greater in the intervention group than in the control group. Given the control of the baseline characteristics, this chance was 5.8 times greater. In addition, it was found that the chance of a negative wet smear test result in the second follow-up was affected by the wet smear test result in the first follow-up. Conclusion: Based on the results of this study, it can be concluded that vaginal gel containing 7.5% propolis extract was more efficient than standard treatment in eradicating infection and preventing the recurrence of infection." @default.
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• W4297021495 date "2022-09-23" @default.
• W4297021495 modified "2023-10-14" @default.
• W4297021495 title "Comparison of the effect of propolis vaginal gel and metronidazole oral tablet on wet smear test results in women suffering from trichomoniasis" @default.
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• W4297021495 doi "https://doi.org/10.21203/rs.3.rs-2084927/v1" @default.
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