Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297178465> ?p ?o ?g. }
- W4297178465 endingPage "101258" @default.
- W4297178465 startingPage "101258" @default.
- W4297178465 abstract "Positive-strand RNA viruses replicate in intracellular membranous structures formed after virus-driven intensive manipulation of subcellular organelles and membranes. These unique structures are called viral-replication organelles (VROs). To build VROs, the replication proteins coded by (+)RNA viruses co-opt host proteins, including membrane-shaping, lipid synthesis, and lipid-modification enzymes to create an optimal microenvironment that (i) concentrates the viral replicase and associated host proteins and the viral RNAs; (ii) regulates enzymatic activities and spatiotemporally the replication process; and (iii) protects the viral RNAs from recognition and degradation by the host innate immune defense. Tomato bushy stunt virus (TBSV), a plant (+)RNA virus, serves as an advanced model to study the interplay among viral components, co-opted host proteins, lipids, and membranes. This review presents our current understanding of the complex interaction between TBSV and host with panviral implications." @default.
- W4297178465 created "2022-09-27" @default.
- W4297178465 creator A5090380640 @default.
- W4297178465 date "2022-10-01" @default.
- W4297178465 modified "2023-10-17" @default.
- W4297178465 title "Co-opted membranes, lipids, and host proteins: what have we learned from tombusviruses?" @default.
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