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- W4297268549 endingPage "1315" @default.
- W4297268549 startingPage "1315" @default.
- W4297268549 abstract "The burden of infections in acute care surgery (ACS) is huge. Surgical emergencies alone account for three million admissions per year in the United States (US) with estimated financial costs of USD 28 billion per year. Acute care facilities and ACS patients represent boost sanctuaries for the emergence, development and transmission of infections and multi-resistant organisms. According to the World Health Organization, healthcare-associated infections affected around 4 million cases in Europe and 1.7 million in the US alone in 2011 with 39,000 and 99,000 directly attributable deaths, respectively. In this scenario, antimicrobial resistance arose as a public-health emergency that worsens patients' morbidity and mortality and increases healthcare costs. The optimal patient care requires the application of comprehensive evidence-based policies and strategies aiming at minimizing the impact of healthcare associated infections and antimicrobial resistance, while optimizing the treatment of intra-abdominal infections. The present review provides a snapshot of two hot topics, such as antimicrobial resistance and systemic inflammatory response, and three milestones of infection management, such as source control, infection prevention, and control and antimicrobial stewardship." @default.
- W4297268549 created "2022-09-28" @default.
- W4297268549 creator A5010758770 @default.
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- W4297268549 creator A5045596998 @default.
- W4297268549 creator A5045875109 @default.
- W4297268549 creator A5055454008 @default.
- W4297268549 date "2022-09-27" @default.
- W4297268549 modified "2023-10-16" @default.
- W4297268549 title "Antimicrobial Challenge in Acute Care Surgery" @default.
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