FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297290036> ?p ?o ?g. }

• W4297290036 endingPage "101345" @default.
• W4297290036 startingPage "101345" @default.
• W4297290036 abstract "The insulin-like androgenic gland-specific peptide is a known primary regulator of sexual differentiation in crustaceans. However, the knowledge of the crucial elements involved in the insulin-like signaling cascade remains fragmented. Here, we characterized a novel insulin-like receptor gene in the white shrimp Penaeus vannamei and named as Pv-IR. The deduced amino acid sequence of Pv-IR contained conserved domains of IRs, including two ligand-binding domains, a furin-like domain, three fibronectin-3 domains, and an intracellular tyrosine kinase domain in order. Multiple sequence alignment of the first ligand-binding domain and the tyrosine kinase domain in Pv-IR revealed a high degree of similarity in all representative IRs. The phylogenetic analysis presented that Pv-IR was clustered into a separate branch with IRs from decapods. The tissue distribution analysis showed that Pv-IR was predominantly expressed in the sperm duct and terminal ampullae of the male reproductive system in P. vannamei. Meanwhile, Pv-IR knockdown was carried out in postlarvae. Although the sex reversal phenotype was not observed, the effects of Pv-IR silencing on the expressions of related-genes were analyzed by the comparative transcriptomic sequencing. Significantly, two down-regulated transcripts (clottable protein and insulin-like peptide) and two up-regulated transcripts (flotillin and thyroid stimulating hormone receptor) were focused as gonad-related differentially expressed unigenes in Pv-IR knockdown. The data provided a more theoretical basis for elucidating the mechanism of sexual differentiation in crustaceans." @default.
• W4297290036 created "2022-09-28" @default.
• W4297290036 creator A5011077396 @default.
• W4297290036 creator A5012147744 @default.
• W4297290036 creator A5032898186 @default.
• W4297290036 creator A5061352985 @default.
• W4297290036 creator A5065540427 @default.
• W4297290036 creator A5072479572 @default.
• W4297290036 creator A5080740258 @default.
• W4297290036 date "2022-12-01" @default.
• W4297290036 modified "2023-10-16" @default.
• W4297290036 title "The characterization and knockdown of a male gonad-specific insulin-like receptor gene in the white shrimp Penaeus vannamei" @default.
• W4297290036 cites W1969768268 @default.
• W4297290036 cites W1981396123 @default.
• W4297290036 cites W1990829061 @default.
• W4297290036 cites W1991987674 @default.
• W4297290036 cites W1998590846 @default.
• W4297290036 cites W2016052444 @default.
• W4297290036 cites W2063140953 @default.
• W4297290036 cites W2064807591 @default.
• W4297290036 cites W2069334580 @default.
• W4297290036 cites W2070416491 @default.
• W4297290036 cites W2072966398 @default.
• W4297290036 cites W2075659581 @default.
• W4297290036 cites W2097518675 @default.
• W4297290036 cites W2104812730 @default.
• W4297290036 cites W2116896735 @default.
• W4297290036 cites W2121370840 @default.
• W4297290036 cites W2129410564 @default.
• W4297290036 cites W2169560653 @default.
• W4297290036 cites W2203944724 @default.
• W4297290036 cites W2211000907 @default.
• W4297290036 cites W2261997787 @default.
• W4297290036 cites W2313957691 @default.
• W4297290036 cites W2560542604 @default.
• W4297290036 cites W2792485367 @default.
• W4297290036 cites W2794825946 @default.
• W4297290036 cites W2898619710 @default.
• W4297290036 cites W2994976411 @default.
• W4297290036 cites W3007452350 @default.
• W4297290036 cites W3010794493 @default.
• W4297290036 cites W3025094964 @default.
• W4297290036 cites W3043615961 @default.
• W4297290036 cites W3132481448 @default.
• W4297290036 cites W2161051422 @default.
• W4297290036 doi "https://doi.org/10.1016/j.aqrep.2022.101345" @default.
• W4297290036 hasPublicationYear "2022" @default.
• W4297290036 type Work @default.
• W4297290036 citedByCount "1" @default.
• W4297290036 countsByYear W42972900362023 @default.
• W4297290036 crossrefType "journal-article" @default.
• W4297290036 hasAuthorship W4297290036A5011077396 @default.
• W4297290036 hasAuthorship W4297290036A5012147744 @default.
• W4297290036 hasAuthorship W4297290036A5032898186 @default.
• W4297290036 hasAuthorship W4297290036A5061352985 @default.
• W4297290036 hasAuthorship W4297290036A5065540427 @default.
• W4297290036 hasAuthorship W4297290036A5072479572 @default.
• W4297290036 hasAuthorship W4297290036A5080740258 @default.
• W4297290036 hasConcept C104317684 @default.
• W4297290036 hasConcept C112446052 @default.
• W4297290036 hasConcept C134018914 @default.
• W4297290036 hasConcept C173396325 @default.
• W4297290036 hasConcept C2776841996 @default.
• W4297290036 hasConcept C2777391703 @default.
• W4297290036 hasConcept C2778160301 @default.
• W4297290036 hasConcept C2779306644 @default.
• W4297290036 hasConcept C505870484 @default.
• W4297290036 hasConcept C54355233 @default.
• W4297290036 hasConcept C86803240 @default.
• W4297290036 hasConcept C95444343 @default.
• W4297290036 hasConceptScore W4297290036C104317684 @default.
• W4297290036 hasConceptScore W4297290036C112446052 @default.
• W4297290036 hasConceptScore W4297290036C134018914 @default.
• W4297290036 hasConceptScore W4297290036C173396325 @default.
• W4297290036 hasConceptScore W4297290036C2776841996 @default.
• W4297290036 hasConceptScore W4297290036C2777391703 @default.
• W4297290036 hasConceptScore W4297290036C2778160301 @default.
• W4297290036 hasConceptScore W4297290036C2779306644 @default.
• W4297290036 hasConceptScore W4297290036C505870484 @default.
• W4297290036 hasConceptScore W4297290036C54355233 @default.
• W4297290036 hasConceptScore W4297290036C86803240 @default.
• W4297290036 hasConceptScore W4297290036C95444343 @default.
• W4297290036 hasLocation W42972900361 @default.
• W4297290036 hasOpenAccess W4297290036 @default.
• W4297290036 hasPrimaryLocation W42972900361 @default.
• W4297290036 hasRelatedWork W1976816236 @default.
• W4297290036 hasRelatedWork W1982569433 @default.
• W4297290036 hasRelatedWork W1997642381 @default.
• W4297290036 hasRelatedWork W2021846212 @default.
• W4297290036 hasRelatedWork W2031272986 @default.
• W4297290036 hasRelatedWork W2039442853 @default.
• W4297290036 hasRelatedWork W2121753467 @default.
• W4297290036 hasRelatedWork W2588203675 @default.
• W4297290036 hasRelatedWork W2779886335 @default.
• W4297290036 hasRelatedWork W2988126587 @default.
• W4297290036 hasVolume "27" @default.
• W4297290036 isParatext "false" @default.
• W4297290036 isRetracted "false" @default.

• next