FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297312390> ?p ?o ?g. }

• W4297312390 abstract "Context Previous studies on the association between thyroid function and carotid plaque have shown contradictory results, which may be attributable to the sensitivity to thyroid hormone indices. This study aimed to analyze the association between thyroid hormone sensitivity and risk of carotid plaque in patients with coronary heart disease (CHD) and further explore this association according to sex, age, smoking, and drinking status. Methods This large-scale, multi-center, retrospective, cross-sectional study included 6679 patients with CHD (age 35–75). Central sensitivity to thyroid hormone was evaluated by the thyroid feedback quantile-based index (TFQI), parametric thyroid feedback quantile-based index (PTFQI), thyroid-stimulating hormone index (TSHI), and thyrotroph thyroxine resistance index (TT4RI). Peripheral sensitivity to thyroid hormone was assessed by free triiodothyronine/free thyroxine (FT3/FT4) ratio. Taking no carotid plaque as a reference, this study used logistic regression to analyze the association between central and peripheral thyroid hormone sensitivity and carotid plaque in patients with CHD. Results Of the 6679 patients with CHD, 4843 (72.50%) had carotid plaque. In the multi-adjusted models, the TFQI (odds ratio [OR]: 1.50; 95% confidence interval [CI]: 1.26–1.78; P &lt; 0.001), PTFQI (OR: 1.76; 95% CI: 1.46–2.12; P &lt; 0.001), TSHI (OR: 1.21; 95% CI: 1.10–1.33; P &lt; 0.001), and TT4RI (OR: 1.00; 95% CI: 1.00–1.01; P = 0.003) were positively associated with the risk of carotid plaque. Compared with that in females and people &gt; 60 years, the OR value for carotid plaque was higher in males and people ≤ 60 years. Similarly, smokers and drinkers had higher OR values for carotid plaque than non-smokers and non-drinkers. Conversely, FT3/FT4 ratio (OR: 0.75; 95% CI: 0.70–0.81; P &lt; 0.001) was negatively associated with carotid plaque, and the OR value for carotid plaque was lower in males, patients ≤ 60 years, smokers, and drinkers. Conclusion This study showed that thyroid hormone sensitivity is significantly associated with carotid plaque in patients with CHD. This association is more significant in males, patients ≤ 60 years, smokers, and drinkers." @default.
• W4297312390 created "2022-09-28" @default.
• W4297312390 creator A5007726323 @default.
• W4297312390 creator A5028753460 @default.
• W4297312390 creator A5029974309 @default.
• W4297312390 creator A5038837596 @default.
• W4297312390 creator A5045814483 @default.
• W4297312390 creator A5051080513 @default.
• W4297312390 creator A5058965019 @default.
• W4297312390 creator A5061145810 @default.
• W4297312390 creator A5076233544 @default.
• W4297312390 creator A5077535167 @default.
• W4297312390 creator A5079782730 @default.
• W4297312390 date "2022-09-27" @default.
• W4297312390 modified "2023-10-18" @default.
• W4297312390 title "Impaired sensitivity to thyroid hormones and carotid plaque in patients with coronary heart disease: A RCSCD-TCM study in China" @default.
• W4297312390 cites W1912615984 @default.
• W4297312390 cites W1983793453 @default.
• W4297312390 cites W1990025046 @default.
• W4297312390 cites W2008114180 @default.
• W4297312390 cites W2008325595 @default.
• W4297312390 cites W2015174411 @default.
• W4297312390 cites W2037507757 @default.
• W4297312390 cites W2051927648 @default.
• W4297312390 cites W2075347532 @default.
• W4297312390 cites W2085305244 @default.
• W4297312390 cites W2088469646 @default.
• W4297312390 cites W2091655302 @default.
• W4297312390 cites W2107175684 @default.
• W4297312390 cites W2112015452 @default.
• W4297312390 cites W2128219988 @default.
• W4297312390 cites W2144716937 @default.
• W4297312390 cites W2154662035 @default.
• W4297312390 cites W2155575761 @default.
• W4297312390 cites W2170285171 @default.
• W4297312390 cites W2195786982 @default.
• W4297312390 cites W2592768592 @default.
• W4297312390 cites W2594066124 @default.
• W4297312390 cites W2615963056 @default.
• W4297312390 cites W2734005608 @default.
• W4297312390 cites W2774294389 @default.
• W4297312390 cites W2902978682 @default.
• W4297312390 cites W2903131156 @default.
• W4297312390 cites W2904867458 @default.
• W4297312390 cites W2912388369 @default.
• W4297312390 cites W2919733427 @default.
• W4297312390 cites W2943307957 @default.
• W4297312390 cites W2945447829 @default.
• W4297312390 cites W2946664098 @default.
• W4297312390 cites W2990526418 @default.
• W4297312390 cites W3018086681 @default.
• W4297312390 cites W3019335011 @default.
• W4297312390 cites W3038622560 @default.
• W4297312390 cites W3086639973 @default.
• W4297312390 cites W3092775771 @default.
• W4297312390 cites W3094756738 @default.
• W4297312390 cites W3106293943 @default.
• W4297312390 cites W3109285518 @default.
• W4297312390 cites W3113371037 @default.
• W4297312390 cites W3122226502 @default.
• W4297312390 cites W3123123295 @default.
• W4297312390 cites W3134406661 @default.
• W4297312390 cites W3136562050 @default.
• W4297312390 cites W3178513695 @default.
• W4297312390 cites W3183790253 @default.
• W4297312390 cites W3208059653 @default.
• W4297312390 cites W3210433510 @default.
• W4297312390 cites W4205830332 @default.
• W4297312390 cites W4205960146 @default.
• W4297312390 cites W4206218224 @default.
• W4297312390 cites W4221120680 @default.
• W4297312390 cites W4251966062 @default.
• W4297312390 cites W4284960721 @default.
• W4297312390 doi "https://doi.org/10.3389/fendo.2022.940633" @default.
• W4297312390 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36237180" @default.
• W4297312390 hasPublicationYear "2022" @default.
• W4297312390 type Work @default.
• W4297312390 citedByCount "4" @default.
• W4297312390 countsByYear W42973123902023 @default.
• W4297312390 crossrefType "journal-article" @default.
• W4297312390 hasAuthorship W4297312390A5007726323 @default.
• W4297312390 hasAuthorship W4297312390A5028753460 @default.
• W4297312390 hasAuthorship W4297312390A5029974309 @default.
• W4297312390 hasAuthorship W4297312390A5038837596 @default.
• W4297312390 hasAuthorship W4297312390A5045814483 @default.
• W4297312390 hasAuthorship W4297312390A5051080513 @default.
• W4297312390 hasAuthorship W4297312390A5058965019 @default.
• W4297312390 hasAuthorship W4297312390A5061145810 @default.
• W4297312390 hasAuthorship W4297312390A5076233544 @default.
• W4297312390 hasAuthorship W4297312390A5077535167 @default.
• W4297312390 hasAuthorship W4297312390A5079782730 @default.
• W4297312390 hasBestOaLocation W42973123901 @default.
• W4297312390 hasConcept C126322002 @default.
• W4297312390 hasConcept C134018914 @default.
• W4297312390 hasConcept C151730666 @default.
• W4297312390 hasConcept C156957248 @default.
• W4297312390 hasConcept C164705383 @default.
• W4297312390 hasConcept C2777886399 @default.
• W4297312390 hasConcept C2779343474 @default.
• W4297312390 hasConcept C526584372 @default.

• next