Matches in SemOpenAlex for { <https://semopenalex.org/work/W4297318882> ?p ?o ?g. }
- W4297318882 endingPage "170" @default.
- W4297318882 startingPage "159" @default.
- W4297318882 abstract "This literature review evaluates the absorption of methionine (Met) sources such as 2-hydroxy-4-methylthiobutyric acid (HMTBa), its calcium salts (HMTBa-Ca), and DL-methionine (DL-Met) by focusing on the state of knowledge regarding the absorption mechanism, experimental methodology, and factors affecting their absorption. The 2 Met sources differ in mechanism and site of absorption due to differences in their chemical characteristics and enzymatic conversion. This review addresses diffusion- and transport-mediated absorption systems for amino acids and carboxylic compounds, best elucidated by in vitro, ex vivo, and in vivo experimental models. Opportunities and limitations in the use of radioisotopes to depict absorption sites as well as host and microbial metabolism are described. Physiological and environmental conditions that lead to changes in gut absorptive capacity and the impact of Met source absorption are also evaluated. This review concludes that any comparison between HMTBa and DL-Met should consider their different behaviors during the absorption phase. Hence, the chemical characteristics of these 2 molecules entail different absorption sites and mechanisms, from passive absorption in the case of HMTBa and HMTBa-Ca to active transporters for DL-Met, HMTBa, and HMTBa-Ca. In addition, the different conversion modes of these 2 molecules further differentiate their absorption modes. Considering these important differences, it is easier to understand the apparent divergence between the conclusions of existing publications. When comparing these 2 molecules, it is recommended to properly adapt to the conditions under which the absorption of Met sources is evaluated." @default.
- W4297318882 created "2022-09-28" @default.
- W4297318882 creator A5009337910 @default.
- W4297318882 creator A5015364384 @default.
- W4297318882 creator A5046713136 @default.
- W4297318882 creator A5048269340 @default.
- W4297318882 creator A5060845692 @default.
- W4297318882 creator A5077480327 @default.
- W4297318882 creator A5090607258 @default.
- W4297318882 date "2023-03-01" @default.
- W4297318882 modified "2023-10-14" @default.
- W4297318882 title "Absorption of methionine sources in animals—is there more to know?" @default.
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